Retinol-binding protein 2
Homo sapiens
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Protein homooligomer Homooligomer Protein × 3 PDB declaration: trimeric（3） Consistent with protein copy count | Chain A； UniProt 2–134 Chain I； UniProt 2–134 Chain K； UniProt 2–134 | Mutation：Q108K, T51D | GOL GLYCEROL × 6 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000 | Resolution 2.78 Å R-free 0.321 |
| 2 | Protein homooligomer Homooligomer Protein × 3 PDB declaration: trimeric（3） Consistent with protein copy count | Chain B； UniProt 2–134 Chain J； UniProt 2–134 Chain L； UniProt 2–134 | Mutation：Q108K, T51D | GOL GLYCEROL × 10 ACT ACETATE ION × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000 | Resolution 2.78 Å R-free 0.321 |
| 3 | Protein homooligomer Homooligomer Protein × 3 PDB declaration: trimeric（3） Consistent with protein copy count | Chain C； UniProt 2–134 Chain E； UniProt 2–134 Chain G； UniProt 2–134 | Mutation：Q108K, T51D | GOL GLYCEROL × 3 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000 | Resolution 2.78 Å R-free 0.321 |
| 4 | Protein homooligomer Homooligomer Protein × 3 PDB declaration: trimeric（3） Consistent with protein copy count | Chain D； UniProt 2–134 Chain F； UniProt 2–134 Chain H； UniProt 2–134 | Mutation：Q108K, T51D | GOL GLYCEROL × 2 ACT ACETATE ION × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000 | Resolution 2.78 Å R-free 0.321 |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 6WP0 | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 12AK Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-6 Deposited 2026-03-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | A1CKY (2Z)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}-4,4,4-trifluorobut-2-enal × 1 ACT ACETATE ION × 1 EDO 1,2-ETHANEDIOL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate 100 mM
|
Resolution 1.37 Å R-free 0.200 |
| 2RCQ Crystal structure of human apo Cellular Retinol Binding Protein II (CRBP-II) Deposited 2007-09-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | SO4 SULFATE ION × 2 TLA L(+)-TARTARIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1 M sodium citrate, 0.2 M sodium/potassium tartrate, 1.4 M ammonium sulphate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.20 Å R-free 0.217 |
| 2RCT Crystal structure of human holo cellular retinol-binding protein II (CRBP-II) Deposited 2007-09-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | SO4 SULFATE ION × 2 RTL RETINOL × 1 TLA L(+)-TARTARIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1 M sodium citrate, 0.2 M sodium/potassium tartrate, 1.4 M ammonium sulfate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.20 Å R-free 0.215 |
| 4EDE Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.4 Angstrom Resolution Deposited 2012-03-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.40 Å R-free 0.242 |
| 4EDE Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.4 Angstrom Resolution Deposited 2012-03-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.40 Å R-free 0.242 |
| 4EEJ Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.5 Angstrom Resolution Deposited 2012-03-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.50 Å R-free 0.208 |
| 4EEJ Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.5 Angstrom Resolution Deposited 2012-03-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.50 Å R-free 0.208 |
| 4EFG Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.58 Angstrom Resolution Deposited 2012-03-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.58 Å R-free 0.242 |
| 4EFG Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.58 Angstrom Resolution Deposited 2012-03-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.58 Å R-free 0.242 |
| 4EXZ Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution Deposited 2012-05-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L | ACT ACETATE ION × 1 RET RETINAL × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.61 Å R-free 0.265 |
| 4EXZ Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution Deposited 2012-05-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L | ACT ACETATE ION × 1 RET RETINAL × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.61 Å R-free 0.265 |
| 4GKC Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal at 1.33 Deposited 2012-08-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,Y19W,R58W,T29L,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；40% PEG 4000, 0.1M CH3COONa.3H2O, 0.1 M CH3COONH4, EVAPORATION, temperature 298K, pH 4.6
|
Resolution 1.30 Å R-free 0.225 |
| 4GKC Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal at 1.33 Deposited 2012-08-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,Y19W,R58W,T29L,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；40% PEG 4000, 0.1M CH3COONa.3H2O, 0.1 M CH3COONH4, EVAPORATION, temperature 298K, pH 4.6
|
Resolution 1.30 Å R-free 0.225 |
| 4QYN The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol Deposited 2014-07-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RTL RETINOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.19 Å R-free 0.216 |
| 4QYN The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol Deposited 2014-07-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.19 Å R-free 0.216 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 ACT ACETATE ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Not recorded | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4RUU Crystal structure of the Q108K:K40L mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal after 24 hour incubation at 1.4 Angstrom Resolution Deposited 2014-11-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：K40L, Q108K | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30 % PEG 4000, 0.1 M Ammonium Acatate, 0.1 M Sodium Acetate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.40 Å R-free 0.238 |
| 4RUU Crystal structure of the Q108K:K40L mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal after 24 hour incubation at 1.4 Angstrom Resolution Deposited 2014-11-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：K40L, Q108K | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30 % PEG 4000, 0.1 M Ammonium Acatate, 0.1 M Sodium Acetate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.40 Å R-free 0.238 |
| 4ZCB Human CRBPII mutant - Y60W dimer Deposited 2015-04-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Fragment：UNP residues 2-134
Chain B
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：Y60W Mutation：Y60W | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG 4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.70 Å R-free 0.239 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZH6 Crystal Structure of the Domain-Swapped Dimer Y60L mutant of Human Cellular Retinol Binding Protein II Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 1.55 Å R-free 0.224 |
| 4ZH9 Crystal Structure of the Domain-Swapped Dimer Wild-Type of Human Cellular Retinol Binding Protein II Deposited 2015-04-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 2.66 Å R-free 0.274 |
| 4ZJ0 The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal Deposited 2015-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：K40L, Y60W, Q108K | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.50 Å R-free 0.251 |
| 4ZJ0 The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal Deposited 2015-04-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：K40L, Y60W, Q108K | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.50 Å R-free 0.251 |
| 4ZR2 Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II Deposited 2015-05-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, Y60W Mutation：Q108K, K40L, Y60W | RET RETINAL × 1 ACT ACETATE ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 1.80 Å R-free 0.218 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Y60L | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Y60L | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DPQ Crystal Structure of E72A mutant of domain swapped dimer Human Cellular Retinol Binding Protein Deposited 2015-09-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：E72A Mutation：E72A | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.77 Å R-free 0.220 |
| 5F58 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution Deposited 2015-12-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58F | RET RETINAL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate pH = 4.5
|
Resolution 1.54 Å R-free 0.229 |
| 5F58 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution Deposited 2015-12-04 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58F | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate pH = 4.5
|
Resolution 1.54 Å R-free 0.229 |
| 5F6B Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution Deposited 2015-12-05 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25 %PEG 4000, 0.1 M Ammonium Acetate, 0.1 M Sodium Acetate pH = 4.5.
|
Resolution 1.31 Å R-free 0.235 |
| 5F6B Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution Deposited 2015-12-05 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25 %PEG 4000, 0.1 M Ammonium Acetate, 0.1 M Sodium Acetate pH = 4.5.
|
Resolution 1.31 Å R-free 0.235 |
| 5F7G Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution Deposited 2015-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W, Q38L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000, 0.1 M Ammonium Acetate, 0.1 M sodium acetate pH = 4.5
|
Resolution 1.48 Å R-free 0.252 |
| 5F7G Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution Deposited 2015-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W, Q38L | RET RETINAL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000, 0.1 M Ammonium Acetate, 0.1 M sodium acetate pH = 4.5
|
Resolution 1.48 Å R-free 0.252 |
| 5FAZ Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution Deposited 2015-12-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30 % PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium acetate pH = 4.5
|
Resolution 1.40 Å R-free 0.255 |
| 5FAZ Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution Deposited 2015-12-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30 % PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium acetate pH = 4.5
|
Resolution 1.40 Å R-free 0.255 |
| 5FEN Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution Deposited 2015-12-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T53C | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH 4.5
|
Resolution 1.55 Å R-free 0.241 |
| 5FEN Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution Deposited 2015-12-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T53C | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH 4.5
|
Resolution 1.55 Å R-free 0.241 |
| 5FFH Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution Deposited 2015-12-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58W, Y19W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate
|
Resolution 1.68 Å R-free 0.267 |
| 5FFH Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution Deposited 2015-12-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58W, Y19W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate
|
Resolution 1.68 Å R-free 0.267 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain E
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain G
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain I
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain J
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 6BTH Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG) Deposited 2017-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | ECB 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 PEG DI(HYDROXYETHYL)ETHER × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.164 |
| 6BTH Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG) Deposited 2017-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | ECB 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.164 |
| 6BTI Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) Deposited 2017-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | E7Y (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide × 1 PEG DI(HYDROXYETHYL)ETHER × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M TrisHCl, PEG 3350 22-28%.
|
Resolution 1.45 Å R-free 0.185 |
| 6BTI Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) Deposited 2017-12-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | E7Y (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M TrisHCl, PEG 3350 22-28%.
|
Resolution 1.45 Å R-free 0.185 |
| 6C7Z Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine Deposited 2018-01-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,R58F | ACT ACETATE ION × 1 JLO (2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH=4.5
|
Resolution 1.42 Å R-free 0.256 |
| 6C7Z Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine Deposited 2018-01-23 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,R58F | ACT ACETATE ION × 1 JLO (2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH=4.5
|
Resolution 1.42 Å R-free 0.256 |
| 6E50 Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51F mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51F | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 1.97 Å R-free 0.266 |
| 6E51 Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51W mutant of human cellular retinol binding protein II Deposited 2018-07-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51W | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, Sodium acetate
|
Resolution 2.26 Å R-free 0.287 |
| 6E5E Crystal structure of the apo domain-swapped dimer Q108K:T51D mutant of human cellular retinol binding protein II Deposited 2018-07-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, T51D | ACT ACETATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, sodium acetate, ammonium acetate
|
Resolution 1.70 Å R-free 0.242 |
| 6E5Q Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H | ACT ACETATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetete
|
Resolution 1.99 Å R-free 0.267 |
| 6E5R Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, A28C, T51D Mutation：Q108K, A28C, T51D | ACT ACETATE ION × 3 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.59 Å R-free 0.281 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain J
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain G
2–134（133 aa）
Chain I
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E6L Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F:Y60A mutant of human cellular retinol binding protein II Deposited 2018-07-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51F, Y60A | ACT ACETATE ION × 2 RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.08 Å R-free 0.248 |
| 6E7M Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D, A28C Mutation：Q108K, T51D, A28C | ACT ACETATE ION × 8 GOL GLYCEROL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.70 Å R-free 0.296 |
| 6E7M Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, T51D, A28C Mutation：Q108K, T51D, A28C | ACT ACETATE ION × 2 GOL GLYCEROL × 2 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.70 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain G
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain I
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain J
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain K
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain L
2–134（133 aa）
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain G
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain H
2–134（133 aa）
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain I
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain J
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MKV Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2 Deposited 2018-09-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K,K40L,T51W Mutation：Q108K,K40L,T51W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.11 Å R-free 0.273 |
| 6MKV Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2 Deposited 2018-09-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K,K40L,T51W Mutation：Q108K,K40L,T51W | RET RETINAL × 2 ACT ACETATE ION × 6 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.11 Å R-free 0.273 |
| 6MLB Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F mutant of human cellular retinol binding protein II Deposited 2018-09-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Fragment：Q108K, K40L, T51F
Chain C
2–134（133 aa）
Fragment：Q108K, K40L, T51F
|
Not recorded | GOL GLYCEROL × 1 ACT ACETATE ION × 2 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.15 Å R-free 0.302 |
| 6MLB Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F mutant of human cellular retinol binding protein II Deposited 2018-09-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Fragment：Q108K, K40L, T51F
Chain D
2–134（133 aa）
Fragment：Q108K, K40L, T51F
|
Not recorded | GOL GLYCEROL × 3 ACT ACETATE ION × 3 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.15 Å R-free 0.302 |
| 6ON5 Crystal Structure of the Zn-bound Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C,F57H Mutation：Q108K,T51D,A28C,L36C,F57H | ZN ZINC ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 3350, Bis-Tris-HCl
|
Resolution 1.64 Å R-free 0.255 |
| 6ON7 Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C Mutation：Q108K,T51D,A28C,L36C | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate
|
Resolution 1.98 Å R-free 0.254 |
| 6ON8 Crystal Structure of the Reduced Form of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C,F57H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；Bis-Tris:HCl, PEG 3350
|
Resolution 2.40 Å R-free 0.258 |
| 6VID The Crystal Structure of Aps Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Variant of HCRBPII Deposited 2020-01-12 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 3 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.89 Å R-free 0.308 |
| 6VID The Crystal Structure of Aps Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Variant of HCRBPII Deposited 2020-01-12 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain C
2–134（133 aa）
Chain E
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.89 Å R-free 0.308 |
| 6VIS The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:V62E Variant of HCRBPII Deposited 2020-01-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E | GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；293 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 2.79 Å R-free 0.298 |
| 6VIT The Crystal Structure of Apo Domain-Swapped dimer Q108K:T51D:I32C Variant of HCRBPII with an Engineered Disulfide Bond Deposited 2020-01-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, T51D, I32C Mutation：Q108K, T51D, I32C | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.4；298 K；citric acid, PEG 3350
|
Resolution 3.20 Å R-free 0.288 |
| 6WNF The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII Deposited 2020-04-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40D,T53A,R58L,Q38F,Q4F,F57H Mutation：Q108K,K40D,T53A,R58L,Q38F,Q4F,F57H | ACT ACETATE ION × 3 GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.67 Å R-free 0.270 |
| 6WNJ The Crystal Structure of Apo Domain-Swapped Trimer Q108K:T51D:A28C:I32C of HCRBPII Deposited 2020-04-22 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,I32C Mutation：Q108K,T51D,A28C,I32C Mutation：Q108K,T51D,A28C,I32C | GOL GLYCEROL × 7 144 TRIS-HYDROXYMETHYL-METHYL-AMMONIUM × 3 SO4 SULFATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；sodium acetate trihydrate, ammonium sulfate
|
Resolution 2.10 Å R-free 0.239 |
| 6WP1 The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII Deposited 2020-04-26 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain E
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K | ACT ACETATE ION × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 2.99 Å R-free 0.302 |
| 6WP1 The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII Deposited 2020-04-26 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K | ACT ACETATE ION × 4 GOL GLYCEROL × 7 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 2.99 Å R-free 0.302 |
| 6WP2 The Crystal Structure of Apo Zinc-Bound Domain Swapped-Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII Deposited 2020-04-26 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H | ZN ZINC ION × 6 GOL GLYCEROL × 5 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；ammonium iodide, PEG 3350
|
Resolution 2.48 Å R-free 0.312 |
| 7JVG Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol Deposited 2020-08-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | 1AG (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, pH 8.0, PEG 3350 25%
|
Resolution 1.40 Å R-free 0.196 |
| 7JVG Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol Deposited 2020-08-21 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | 1AG (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, pH 8.0, PEG 3350 25%
|
Resolution 1.40 Å R-free 0.196 |
| 7JVY Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether Deposited 2020-08-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VKV 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, PEG 3350 25%
|
Resolution 1.30 Å R-free 0.166 |
| 7JVY Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether Deposited 2020-08-24 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VKV 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, PEG 3350 25%
|
Resolution 1.30 Å R-free 0.166 |
| 7JWD Cellular retinol-binding protein 2 (CRBP2) in complex with 2-linoleoylglycerol Deposited 2020-08-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VL7 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.148 |
| 7JWD Cellular retinol-binding protein 2 (CRBP2) in complex with 2-linoleoylglycerol Deposited 2020-08-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VL7 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.148 |
| 7JWR Cellular retinol-binding protein 2 (CRBP2) in complex with 2-oleoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | YOG 1,3-dihydroxypropan-2-yl (9Z)-octadec-9-enoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.30 Å R-free 0.174 |
| 7JWR Cellular retinol-binding protein 2 (CRBP2) in complex with 2-oleoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | YOG 1,3-dihydroxypropan-2-yl (9Z)-octadec-9-enoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.30 Å R-free 0.174 |
| 7JX2 Cellular retinol-binding protein 2 (CRBP2) in complex with 2-palmitoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VLP 1,3-dihydroxypropan-2-yl hexadecanoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.80 Å R-free 0.256 |
| 7JZ5 Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachodonoyl-1-thio-glycerol Deposited 2020-09-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VPY S-[(2R)-2,3-dihydroxypropyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.57 Å R-free 0.183 |
| 7JZ5 Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachodonoyl-1-thio-glycerol Deposited 2020-09-01 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VPY S-[(2R)-2,3-dihydroxypropyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.57 Å R-free 0.183 |
| 7K3I Cellular retinol-binding protein 2 (CRBP2) in complex with 2-lauroylglycerol Deposited 2020-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VLZ 1,3-dihydroxypropan-2-yl dodecanoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；Tris/HCl Ph 8.0, PEG3350 20%-25%
|
Resolution 1.20 Å R-free 0.206 |
| 7LHM Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal Deposited 2021-01-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A,Q38L | ACT ACETATE ION × 1 RET RETINAL × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.50 Å R-free 0.222 |
| 7LHM Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal Deposited 2021-01-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A,Q38L | ACT ACETATE ION × 1 RET RETINAL × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.50 Å R-free 0.222 |
| 7LHN Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light Deposited 2021-01-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 2.11 Å R-free 0.264 |
| 7LHN Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light Deposited 2021-01-25 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 2.11 Å R-free 0.264 |
| 7LHO Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark Deposited 2021-01-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, evaporation, temperature 298K
|
Resolution 1.40 Å R-free 0.196 |
| 7LHO Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark Deposited 2021-01-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, evaporation, temperature 298K
|
Resolution 1.40 Å R-free 0.196 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFY The Crystal Structure of Q108K:K40L:T51V:T53S:R58W:Y19W:A33W:L117E Mutant of HCRBPII Bound with LizFluor Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y19W, A33W, K40L, T51V, T53S, R58W, Q108K, L117E | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 1.26 Å R-free 0.181 |
| 7MFZ The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with LizFluor3 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-12 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K | ZFP 1-(4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}phenyl)azetidine × 3 ACT ACETATE ION × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate , ammonium acetate
|
Resolution 2.49 Å R-free 0.284 |
| 7UCN The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:H:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 1.96 Angstrom Resolution Deposited 2022-03-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q109K Mutation：A28C, L36C, T51D, Q109K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 1.96 Å R-free 0.268 |
| 7UCS The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:H:H:H:R58 Mutant of hCRBPII with Histidine Insertion in the Hinge Loop Region at 1.92 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；Sodium acetate, PEG4000, ammonium acetate
|
Resolution 1.92 Å R-free 0.229 |
| 7UCT The Crystal Structure of Apo Domain-Swapped Dimer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 2.5 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q108K, Q114K Mutation：A28C, L36C, T51D, Q108K, Q114K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 2.52 Å R-free 0.238 |
| 7UCV The Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28CL36C R58:H:H:H:N59 HCRBPII with Histidine Insertion in the Hinge Loop Region at 2.19 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 2.19 Å R-free 0.266 |
| 7UCZ The Crystal Structure of Apo Monomer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.1 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；289 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 1.08 Å R-free 0.213 |
| 7UCZ The Crystal Structure of Apo Monomer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.1 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；289 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 1.08 Å R-free 0.213 |
| 7UD1 The Crystal Structure of Apo Monomer F57:H:H:H:R58 HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.3 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.32 Å R-free 0.212 |
| 7UD1 The Crystal Structure of Apo Monomer F57:H:H:H:R58 HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.3 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.32 Å R-free 0.212 |
| 7UD3 The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:W:W:W:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 2.36 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, Sodium acetate, ammonium acetate
|
Resolution 2.37 Å R-free 0.258 |
| 7UD3 The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:W:W:W:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 2.36 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, Sodium acetate, ammonium acetate
|
Resolution 2.37 Å R-free 0.258 |
| 8D6H Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V after UV irradiation Deposited 2022-06-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51C, T53A, R58L, Q38F, Q4F | GOL GLYCEROL × 11 ACT ACETATE ION × 3 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；293 K；PEG 4000, Ammonium Acetate, Sodium Acetate pH 4.0 - 4.8
|
Resolution 1.60 Å R-free 0.262 |
| 8D6L Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51C, T53A, R58L, Q38F, Q4F | GOL GLYCEROL × 4 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.69 Å R-free 0.283 |
| 8D6N Q108K:K40L:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-06 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 3 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 GOL GLYCEROL × 7 MLA MALONIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.233 |
| 8DB2 Q108K:K40L:T51C:T53A:R58L:Q38F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51C,T53A,R58L,Q38F | RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.50 Å R-free 0.268 |
| 8DN1 Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V at pH 7.2 Deposited 2022-07-10 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | GOL GLYCEROL × 2 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；293 K；25% PEG 4000, ammonium acetate, sodium acetate pH 4.0 - 4.8
|
Resolution 1.32 Å R-free 0.217 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZY Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58Y | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.34 Å R-free 0.282 |
| 8VZY Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58Y | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.34 Å R-free 0.282 |
| 8VZZ Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.22 Å R-free 0.183 |
| 8VZZ Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.22 Å R-free 0.183 |
| 8W00 Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W:L117E | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, sodium acetate, ammonium aceate
|
Resolution 1.23 Å R-free 0.185 |
| 8W00 Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W:L117E | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, sodium acetate, ammonium aceate
|
Resolution 1.23 Å R-free 0.185 |
| 8W02 Q108K:K40L:T51V:T53S:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, PEG 4000, sodium acetate
|
Resolution 1.50 Å R-free 0.237 |
| 8W02 Q108K:K40L:T51V:T53S:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, PEG 4000, sodium acetate
|
Resolution 1.50 Å R-free 0.237 |
| 9D8M Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V fluorophore in the dark state at pH 4 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.20 Å R-free 0.204 |
| 9D8M Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V fluorophore in the dark state at pH 4 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.20 Å R-free 0.204 |
| 9D8N Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 4 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 ACY ACETIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.30 Å R-free 0.224 |
| 9D8N Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 4 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.30 Å R-free 0.224 |
| 9D8O Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII in complex with FR1V in the dark state at pH 3.0 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 3 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.32 Å R-free 0.237 |
| 9D8O Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII in complex with FR1V in the dark state at pH 3.0 Deposited 2024-08-19 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 1 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.32 Å R-free 0.237 |
| 9DDU Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.60 Å R-free 0.218 |
| 9DDU Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 2 GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.60 Å R-free 0.218 |
| 9DE1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 6.0 Deposited 2024-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACT ACETATE ION × 1 GOL GLYCEROL × 2 MLI MALONATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.40 Å R-free 0.209 |
| 9DE1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 6.0 Deposited 2024-08-28 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 MLI MALONATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.40 Å R-free 0.209 |
| 9DF1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 7.6 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 MLA MALONIC ACID × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.52 Å R-free 0.232 |
| 9DF1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 7.6 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 MLA MALONIC ACID × 3 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.52 Å R-free 0.232 |
| 9DF8 Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 2 GOL GLYCEROL × 3 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.78 Å R-free 0.229 |
| 9DF8 Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 2 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.78 Å R-free 0.229 |
| 9DFB Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 3.0 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 EDO 1,2-ETHANEDIOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.71 Å R-free 0.252 |
| 9DFB Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 3.0 Deposited 2024-08-29 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.71 Å R-free 0.252 |
| 9O3M K40F mutant of hCRBPII bound to fentanyl Deposited 2025-04-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：K40F | ACT ACETATE ION × 1 GOL GLYCEROL × 3 7V7 N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.231 |
| 9O3M K40F mutant of hCRBPII bound to fentanyl Deposited 2025-04-07 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：K40F | GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.231 |
| 9PN1 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal Deposited 2025-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:Y19W:T53C:R58W:T29L:Q4A | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.26 Å R-free 0.221 |
| 9PN1 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal Deposited 2025-07-18 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:Y19W:T53C:R58W:T29L:Q4A | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.26 Å R-free 0.221 |
| 9PSV Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-7 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKU (2E)-3-[5-(dimethylamino)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.51 Å R-free 0.231 |
| 9PSV Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-7 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKU (2E)-3-[5-(dimethylamino)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.51 Å R-free 0.231 |
| 9PSW Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-2 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKV (2E)-3-{5-[4-(azetidin-1-yl)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.61 Å R-free 0.198 |
| 9PSX Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-3 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKW (2E)-3-[5-(4-methoxyphenyl)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.29 Å R-free 0.186 |
| 9PSY Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-1 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117 | A1CKX (2E)-3-(5-phenylthiophen-2-yl)but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.62 Å R-free 0.245 |
| 9PSY Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-1 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117 | A1CKX (2E)-3-(5-phenylthiophen-2-yl)but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.62 Å R-free 0.245 |
| 9PT0 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-8 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKZ (2E)-3-[5'-(dimethylamino)[2,2'-bithiophen]-5-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.64 Å R-free 0.223 |
| 9PT1 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-10 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CK0 (2E)-3-{4-[5-(dimethylamino)thiophen-2-yl]phenyl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.48 Å R-free 0.195 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
101 other PDB entries and 197 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | RET2_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–133； UniProt 2–134 Author chain B； PDBConstruct 1–133； UniProt 2–134 Author chain C； PDBConstruct 1–133； UniProt 2–134 Author chain D； PDBConstruct 1–133； UniProt 2–134 Author chain E； PDBConstruct 1–133； UniProt 2–134 Author chain F； PDBConstruct 1–133； UniProt 2–134 Author chain G； PDBConstruct 1–133； UniProt 2–134 Author chain H； PDBConstruct 1–133； UniProt 2–134 Author chain I； PDBConstruct 1–133； UniProt 2–134 Author chain J； PDBConstruct 1–133； UniProt 2–134 Author chain K； PDBConstruct 1–133； UniProt 2–134 Author chain L； PDBConstruct 1–133； UniProt 2–134 |
