SAXSdb — 9iun

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1. Protein Identity and Related Structures Protein Identity & Related Structures

E3 ubiquitin/ISG15 ligase TRIM25

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 6	water × 6	Consistent with protein count
2	Protein homooligomer	Homooligomer	Protein 6	water × 6	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TRI25_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 2–199； UniProt 433–630 Author chain B； PDBConstruct 2–199； UniProt 433–630 Author chain C； PDBConstruct 2–199； UniProt 433–630 Author chain D； PDBConstruct 2–199； UniProt 433–630 Author chain E； PDBConstruct 2–199； UniProt 433–630 Author chain F； PDBConstruct 2–199； UniProt 433–630 Author chain G； PDBConstruct 2–199； UniProt 433–630 Author chain H； PDBConstruct 2–199； UniProt 433–630 Author chain I； PDBConstruct 2–199； UniProt 433–630 Author chain J； PDBConstruct 2–199； UniProt 433–630 Author chain K； PDBConstruct 2–199； UniProt 433–630 Author chain L； PDBConstruct 2–199； UniProt 433–630

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9iun
Deposition date deposition_date	2024-07-22
Last revision last_revision	2025-07-30
Structure title title	Crystal structure of Trim25 Pspry
Keywords keywords	Trim25, LIGASE; LIGASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9iun__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9iun__assembly_2__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9iun__assembly_2__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	38.25 Å
Rg (electron density)	38.07 Å
Total Rg	38.43 Å
Atom count	9486
Residues	1175
Excluded volume	169600 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9iun__assembly_1__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`9iun__assembly_2__model_1`	hexameric （6）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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Unit-cell length a length_a	182.015 Å
Unit-cell length b length_b	182.015 Å
Unit-cell length c length_c	221.320 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	72

Space group space_group	P 31 2 1
Space-group number int_tables_number	152
Crystal system crystal_system	—

Resolution resolution	2.698 Å
Low-resolution limit resolution_low	47.510 Å
R factor r_factor	—
R_work r_work	0.2117
R_free r_free	0.2648

Description description	E3 ubiquitin/ISG15 ligase TRIM25
Molecular weight formula_weight	23575.1 kDa
EC 编号 ec_number	6.3.2.-,2.3.2.27
Source method src_method	man
Copy count entity_count	12

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L
Atom count atom_count	19317

Crystal structure of Trim25 Pspry

1. Protein Identity and Related Structures Protein Identity & Related Structures

E3 ubiquitin/ISG15 ligase TRIM25

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9iun__assembly_2__model_1

9iun__assembly_2__model_1 | I(q)

9iun__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	345

Crystal structure of Trim25 Pspry

1. Protein Identity and Related Structures Protein Identity & Related Structures

E3 ubiquitin/ISG15 ligase TRIM25

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

9iun__assembly_2__model_1

9iun__assembly_2__model_1 | I(q)

9iun__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

7. Citations (1)