← Back to search
9mx9

Crystal structure of the DNA binding domain of FLI1 (F362A) in complex with a DNA containing two contiguous GGAA sites

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Friend leukemia integration 1 transcription factor

Homo sapiens

UniProt Q01543

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*GP*AP*AP*GP*TP*G)-3') ; × 1 ;DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3') ; × 1 CALCIUM ION × 5 water × 2 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1fli 1x66 2ytu

3 assemblies

Homodimer
5e8g 5e8g 9cp6

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5e8i 5e8i 5jvt 5jvt 5jvt 6vg2 6vg2 6vg8 6vgd 9mwy 9mx8 9mx9

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name FLI1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–145； UniProt 259–399 Author chain D； PDBConstruct 5–145； UniProt 259–399

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id9mx9
Deposition date deposition_date2025-01-17
Structure title titleCrystal structure of the DNA binding domain of FLI1 (F362A) in complex with a DNA containing two contiguous GGAA sites
Keywords keywords;Ewing sarcoma, transcription factor, oncogenesis, bone tumor, drug target, deregulation, DNA BINDING PROTEIN-DNA complex, DNA BINDING PROTEIN ;; DNA BINDING PROTEIN/DNA
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9mx9__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9mx9__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9mx9__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.63 Å
Rg (electron density)19.16 Å
Total Rg19.86 Å
Atom count2113
Residues213
Excluded volume35642 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9mx9__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (5)

▶

7. Citations (1)