Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 21378.9 kDa |
| ec_number | 3.6.5.2 |
| mutation | G12C variant, C51S, C80L, C118S |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | A,B |
| atom_count | 5715 |
MHHHHHHGENLYFQGSTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKGNS
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli |
Entity 2
non-polymer
| description | 1-(4-{(7M)-7-[6-amino-3-(trifluoromethyl)pyridin-2-yl]-6-chloroquinazolin-4-yl}piperazin-1-yl)propan-1-one |
| formula_weight | 464.9 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 3
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 4
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 5
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 255 |
