Entity 1
polymer
| description | GTPase KRas |
| formula_weight | 19352.8 kDa |
| mutation | G12C; C51S; C80L; C118S |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | A,B |
| atom_count | 3148 |
GMTEYKLVVVGACGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli BL21(DE3) |
Entity 2
non-polymer
| description | CALCIUM ION |
| formula_weight | 40.1 kDa |
| src_method | nat |
| entity_count | 4 |
Entity 3
non-polymer
| description | ;1-((2R,5S)-4-((S)-6-chloro-7-(1,6-dimethyl-1H-indazol-7-yl)-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-2,5-dimethylpiperazin-1-yl)prop-2-en-1-one
; |
| formula_weight | 608.1 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 4
non-polymer
| description | GLYCEROL |
| formula_weight | 92.1 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 5
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 270 |
