Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 19461.8 kDa |
| ec_number | 3.6.5.2 |
| mutation | G13D, C51S, C80L, C118S |
| src_method | man |
| entity_count | 1 |
Polymer
| type | polypeptide(L) |
| strand_id | A |
| atom_count | 1612 |
GPMTEYKLVVVGAGDVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli |
Entity 2
non-polymer
| description | ;(3R)-1-[(7P)-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-7-(3-hydroxynaphthalen-1-yl)pyrido[4,3-d]pyrimidin-4-yl]piperidin-3-ol
; |
| formula_weight | 547.6 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 3
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 4
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 5
non-polymer
| description | PHOSPHATE ION |
| formula_weight | 95.0 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 160 |
