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9u50

GDP-bound KRAS G12V in complex with MCB-294

Method: X-RAY DIFFRACTION Dmax: 76.2 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9u50

P(r) Distribution

P(r) distribution for 9u50

1. Structure Basics

entry_id9u50
deposition_date2025-03-20
titleGDP-bound KRAS G12V in complex with MCB-294
keywordsGDP-bound, inhibitor, ONCOPROTEIN; ONCOPROTEIN
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier25.41
rg_electron24.68
i0118445000.00
molecular_weight56295.0 kDa
excluded_volume53809 ų
envelope_volume88473 ų
shell_volume29816 ų
envelope_diameter81.0
shell_rg32.28
envelope_rg24.58
shape_rg24.65
total_rg25.31
total_atoms4237
n_residues503
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax76.2
rg_real25.31
rg_real_error0.39
i0_real1.1840e+08
i0_real_error1.5290e+06
rg_reciprocal25.35
i0_reciprocal118400000.0000
total_estimate0.9130
solution_quality EXCELLENT a EXCELLENT solution
n_peaks2
r_peak_primary29.5
skewness0.188
kurtosis-0.569
angular_range— – 0.3100 −1
current_alpha0.0000
highest_alpha14480000.0000
n_real_points63
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.974; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.998; Smooth: 0.944

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)