Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 19714.2 kDa |
| ec_number | 3.6.5.2 |
| src_method | man |
| entity_count | 1 |
Polymer
| type | polypeptide(L) |
| strand_id | A |
| atom_count | 1641 |
GAGAGAMTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli BL21(DE3) |
Entity 2
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 3
non-polymer
| description | ;(3~{R})-1-[2-[[(8~{S})-6-[bis(fluoranyl)methylidene]-2,3,5,7-tetrahydro-1~{H}-pyrrolizin-8-yl]methoxy]-7-(8-ethynyl-7-fluoranyl-3-oxidanyl-naphthalen-1-yl)-8-fluoranyl-pyrido[4,3-d]pyrimidin-4-yl]-3-methyl-piperidin-3-ol
; |
| formula_weight | 633.6 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 4
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 5
non-polymer
| description | DI(HYDROXYETHYL)ETHER |
| formula_weight | 106.1 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 182 |
