Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 19445.9 kDa |
| ec_number | 3.6.5.2 |
| mutation | G12V, C51S, C80L, C118S |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | A,B |
| atom_count | 2910 |
GPMTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli |
Entity 2
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 3
non-polymer
| description | ;methyl {(3R)-1-[(7P)-7-(7,8-difluoro-3-hydroxynaphthalen-1-yl)-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-4-yl]-3-methylpiperidin-3-yl}carbamate
; |
| formula_weight | 654.7 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 4
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 5
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 82 |
