Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 21501.2 kDa |
| ec_number | 3.6.5.2 |
| mutation | G12D |
| src_method | man |
| entity_count | 1 |
Polymer
| type | polypeptide(L) |
| strand_id | A |
| atom_count | 1742 |
MGSSHHHHHHSSGLVPRGSHMTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli BL21(DE3) |
Entity 2
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 3
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 4
non-polymer
| description | ;(6~{S})-4-[7-(8-ethynyl-3-oxidanyl-naphthalen-1-yl)-6,8-bis(fluoranyl)-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]quinazolin-4-yl]-6-methyl-1,4-oxazepan-6-ol
; |
| formula_weight | 618.6 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 5
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 243 |
