Entity 1
polymer
| description | Isoform 2B of GTPase KRas |
| formula_weight | 19445.9 kDa |
| ec_number | 3.6.5.2 |
| mutation | G12V, C51S, C80L, C118S |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | A,B |
| atom_count | 3250 |
GPMTEYKLVVVGAVGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETSLLDILDTAGQEEYSAMRDQYMRTGEGFLLVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKSDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli |
Entity 2
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 3
non-polymer
| description | ;(10R,14S,21P)-3,25-difluoro-16-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}-23-hydroxy-10-methyl-5,6,10,11,12,13-hexahydro-4H-10,14-methano-21,18-(metheno)naphtho[1,8-no]pyrimido[4,5-i][1,3,8,12]oxatriazacyclononadecin-8(9H)-one
; |
| formula_weight | 662.7 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 4
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 5
non-polymer
| description | SULFATE ION |
| formula_weight | 96.1 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 363 |
