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9usb

GppNHp-bound KRAS G12D in complex with MCB-294

Method: X-RAY DIFFRACTION Dmax: 76.6 Å Quality: EXCELLENT

SAXS Profile

SAXS profile for 9usb

P(r) Distribution

P(r) distribution for 9usb

1. Structure Basics

entry_id9usb
deposition_date2025-05-01
titleGppNHp-bound KRAS G12D in complex with MCB-294
keywordsGppNHp-bound, inhibitor, ONCOPROTEIN; ONCOPROTEIN
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier25.33
rg_electron24.60
i0120054000.00
molecular_weight56348.0 kDa
excluded_volume53648 ų
envelope_volume87154 ų
shell_volume29451 ų
envelope_diameter79.3
shell_rg32.15
envelope_rg24.53
shape_rg24.57
total_rg25.23
total_atoms4234
n_residues501
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax76.6
rg_real25.24
rg_real_error0.39
i0_real1.2010e+08
i0_real_error1.7540e+06
rg_reciprocal25.27
i0_reciprocal120100000.0000
total_estimate0.9132
solution_quality EXCELLENT a EXCELLENT solution
n_peaks2
r_peak_primary29.2
skewness0.178
kurtosis-0.580
angular_range— – 0.3150 −1
current_alpha0.0000
highest_alpha13950000.0000
n_real_points64
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.971; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 1.000; Smooth: 0.955

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)