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9q71

Structure of the Measles Virus Fusion Glycoprotein Ectodomain in Postfusion Conformation Bound to Neutralizing Antibody H8

Method: ELECTRON MICROSCOPY D_max: 176.6 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9q71
deposition_date	2025-08-22
title	Structure of the Measles Virus Fusion Glycoprotein Ectodomain in Postfusion Conformation Bound to Neutralizing Antibody H8
keywords	;VIRAL PROTEIN, glycoprotein, immune system, measles, high-resolution, ectodomain, fusion, antibody, complex, VIRAL PROTEIN-IMMUNE SYSTEM complex ;; VIRAL PROTEIN/IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	50.46 Å
rg_electron	50.17 Å
i0	643304000.00
molecular_weight	210900.0 kDa
excluded_volume	264640 Å³
envelope_volume	360310 Å³
shell_volume	66204 Å³
envelope_diameter	175.7 Å
shell_rg	47.96 Å
envelope_rg	50.32 Å
shape_rg	50.16 Å
total_rg	50.12 Å
total_atoms	14828
n_residues	1919
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	176.6 Å
rg_real	50.69 Å
rg_real_error	1.58 Å
i0_real	6.4330e+08
i0_real_error	1.2600e+07
rg_reciprocal	50.26 Å
i0_reciprocal	642900000.0000
total_estimate	0.5698
solution_quality	REASONABLE a REASONABLE solution
n_peaks	1
r_peak_primary	57.0 Å
skewness	0.488
kurtosis	-0.204
angular_range	— – 0.1550 Å⁻¹
current_alpha	0.0001
highest_alpha	40180000.0000
n_real_points	32
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.813; Stabil: 1.000; Sysdev: 0.029; Positv: 1.000; Valcen: 0.878; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (4)

Entity 1 polymer

description	Fusion glycoprotein F0
formula_weight	57379.5 kDa
src_method	man
entity_count	6

Polymer

type	polypeptide(L)
strand_id	A,B,C,D,E,F
atom_count	14828

MGLKVNVSAIFMAVLLTLQTPTGQIHWGNLSKIGVVGIGSASYKVMTRSSHQSLVIKLMPNITLLNNCTRVEIAEYRRLLRTVLEPIRDALNAMTQNIRPVQSVASSRRHKRFAGVVLAGAALGVATAAQITAGIALHQSMLNSQAIDNLRASLETTNQAIEAIRQAGQGMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEILSLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRGIKARITHVDTESYFIVLSIAYPTLSEIKGVIVHRLEGVSYNIGSQEWYTTVPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTKSCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIINQDPDKILTYIAADHCPVVEVNGVTIQVGSRRYPDAVYLHRIDLGPPISLGRLDVGTNLGNAIAKLEDAKELLESSDQILRSMKGLSSTSIGVDDDDKAGWSHPQFEKGGGSGGGSGGGSWSHPQFEK

Source

organism	Measles morbillivirus
ncbi_taxonomy_id	11234
host_organism	Drosophila melanogaster

Entity 2 polymer

description	mAb H8 heavy chain
formula_weight	51896.4 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	G,I,K

MGWSCIILFLVATATGVHSQVQLQQSGAELVRPGTSVKISCKASGYTFINYWLGWVKQRPGHGLEWIGDIYPGGGHTKYNEKFKGKATLTADTSSSTAYMQLSSLTSEDSAVFFCARSGVGSSYYYWGQGTTLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKGLEVLFQGPTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

Source

organism	Mus musculus
ncbi_taxonomy_id	10090
host_organism	Cricetulus griseus

Entity 3 polymer

description	mAb H8 light chain
formula_weight	25641.6 kDa
src_method	man
entity_count	3

Polymer

type	polypeptide(L)
strand_id	H,J,L

MGWSCIILFLVATATGVHSDIVLTQSPASLAVSLGQRATISCRASKSVSSSGYSFLHWYQQKPGQPPKLLIYLASNLDSGVPARFSGSGSGTDFTLNIHPVEEEDATTYYCQHSWELPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC

Source

organism	Mus musculus
ncbi_taxonomy_id	10090
host_organism	Cricetulus griseus

Entity 4 non-polymer

description	2-acetamido-2-deoxy-beta-D-glucopyranose
formula_weight	221.2 kDa
src_method	syn
entity_count	9

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	triclinic

resolution	2.80 Å
resolution_method	—
num_particles	312000

fit	/app/data/saxs_computation/q7/9q71/9q71.fit
pddf	/app/data/pr_computation/q7/9q71/9q71.pr.out
profile	/app/data/saxs_computation/q7/9q71/9q71.dat

Structure of the Measles Virus Fusion Glycoprotein Ectodomain in Postfusion Conformation Bound to Neutralizing Antibody H8

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (4)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

Entity 4 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)