← Back to search

9q78

Crystal structure of T. cruzi EIF4E6 in complex with EIF4G5 peptide

Method: X-RAY DIFFRACTION D_max: 109.8 Å Quality: EXCELLENT

SAXS Profile

P(r) Distribution

▼

1. Structure Basics

entry_id	9q78
deposition_date	2025-08-22
last_revision	2026-01-21
title	Crystal structure of T. cruzi EIF4E6 in complex with EIF4G5 peptide
keywords	TRANSLATION INITIATION FACTOR, EIF4E FAMILY, EIF4E6, EIF4G5, TRANSLATION; TRANSLATION
method	X-RAY DIFFRACTION

▼

Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

▼

2. SAXS Parameters (CRYSOL)

rg_guinier	34.87 Å
rg_electron	34.13 Å
i0	121895000.00
molecular_weight	92014.0 kDa
excluded_volume	116450 Å³
envelope_volume	151320 Å³
shell_volume	36720 Å³
envelope_diameter	108.8 Å
shell_rg	41.31 Å
envelope_rg	33.18 Å
shape_rg	34.12 Å
total_rg	34.71 Å
total_atoms	6512
n_residues	799
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

▼

3. P(r) Analysis (GNOM)

dmax	109.8 Å
rg_real	34.83 Å
rg_real_error	0.80 Å
i0_real	1.2190e+08
i0_real_error	1.9680e+06
rg_reciprocal	34.86 Å
i0_reciprocal	121900000.0000
total_estimate	0.9020
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	29.3 Å
skewness	0.145
kurtosis	-0.813
angular_range	— – 0.2250 Å⁻¹
current_alpha	0.0000
highest_alpha	37910000.0000
n_real_points	46
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.929; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.972; Smooth: 0.962

▶

4. Crystallography & Experiment

▶

5. Entities & Polymer Info (3)

Entity 1 polymer

description	Putative Eukaryotic translation initiation factor 4E type 6
formula_weight	21401.3 kDa
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	C,A,G,E
atom_count	6832

MSAQTSSQPHPLKDRWFVTYFPFVRQKKKGKDFDEQQKPKELDWVTTAEELYATINSFPSLVLLPSDDNLVFARNKVEPYFENFPEGDRVCVFTRTKAQSEQAVVLVLAAVMGEHLRSVTNSECVADVVRIAHKPGNVYPESLRVEVWLHKSDFCEKVVQYFVELFKTYPGIRVARRPISSEVTAD

Source

organism	Trypanosoma cruzi Dm28c
ncbi_taxonomy_id	1416333
host_organism	Escherichia coli BL21(DE3)

Entity 2 polymer

description	Eukaryotic translation initiation factor 4 gamma 5
formula_weight	5706.4 kDa
src_method	man
entity_count	4

Polymer

type	polypeptide(L)
strand_id	D,B,H,F

MEPPAASHPANCIYDIAEFVKCQHTKESPPKGILDFVTELWKEHHHHHH

Source

organism	Trypanosoma cruzi
ncbi_taxonomy_id	5693
host_organism	Escherichia coli BL21(DE3)

Entity 3 water

description	water
formula_weight	18.0 kDa
src_method	nat
entity_count	234

▶

6. Citations (1)

▶

length_a	39.893 Å
length_b	112.694 Å
length_c	100.024 Å
angle_alpha	90.00 °
angle_beta	97.96 °
angle_gamma	90.00 °
z_pdb	8

space_group	P 1 21 1
int_tables_number	4
crystal_system	—

resolution	2.100 Å
resolution_low	49.580 Å
r_factor	0.2045
r_work	0.2011
r_free	0.2698

fit	/app/data/saxs_computation/q7/9q78/9q78.fit
pddf	/app/data/pr_computation/q7/9q78/9q78.pr.out
profile	/app/data/saxs_computation/q7/9q78/9q78.dat

Crystal structure of T. cruzi EIF4E6 in complex with EIF4G5 peptide

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

Diffraction

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 water

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)