9q8t
Nociceptive properties of U5-theraphotoxin-Hs1b, a novel peptide from the Cyriopagopus schmidti spider, active on NaV1.7 channel
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9q8t |
| deposition_date | 2025-02-25 |
| last_revision | 2026-03-11 |
| title | Nociceptive properties of U5-theraphotoxin-Hs1b, a novel peptide from the Cyriopagopus schmidti spider, active on NaV1.7 channel |
| keywords | Spider peptide; U5-theraphotoxin-Hs1b; Nav1.7; pain; venom screening;, TOXIN; TOXIN |
| method | SOLUTION NMR |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 7.65 Å |
| rg_electron | 8.25 Å |
| i0 | 73930900.00 |
| molecular_weight | 70362.0 kDa |
| excluded_volume | 86823 ų |
| envelope_volume | 9698 ų |
| shell_volume | 8110 ų |
| envelope_diameter | 33.0 Å |
| shell_rg | 15.91 Å |
| envelope_rg | 10.57 Å |
| shape_rg | 8.27 Å |
| total_rg | 8.47 Å |
| total_atoms | 9240 |
| n_residues | 620 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 29.7 Å |
| rg_real | 7.64 Å |
| rg_real_error | 0.45 Å |
| i0_real | 7.3930e+07 |
| i0_real_error | 7.5650e+05 |
| rg_reciprocal | 7.64 Å |
| i0_reciprocal | 73930000.0000 |
| total_estimate | 0.7741 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 3 |
| r_peak_primary | 8.7 Å |
| skewness | 0.437 |
| kurtosis | 0.164 |
| angular_range | — – 0.5000 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 34490.0000 |
| n_real_points | 80 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.452; Stabil: 0.993; Sysdev: 1.000; Positv: 1.000; Valcen: 0.802; Smooth: 0.922 |