9qeh

Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Large ribosomal subunit protein bL33A

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL331_STAA3
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 1； PDBConstruct 1–52； UniProt 1–52

Large ribosomal subunit protein bL34

OrganismNot specified

UniProt Q2FDE6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL34_STAA3
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain 2； PDBConstruct 1–45； UniProt 1–45

Large ribosomal subunit protein bL35

OrganismNot specified

UniProt Q2FG57

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL35_STAA3
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain 3； PDBConstruct 1–66； UniProt 1–66

Large ribosomal subunit protein bL36

OrganismNot specified

UniProt Q2FER2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL36_STAA3
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain 4； PDBConstruct 1–37； UniProt 1–37

Large ribosomal subunit protein bL17

OrganismNot specified

UniProt Q2FER6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL17_STAA3
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain L； PDBConstruct 1–122； UniProt 1–122

Large ribosomal subunit protein uL2

OrganismNot specified

UniProt Q2FEP2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL2_STAA3
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain C； PDBConstruct 1–277； UniProt 1–277

Large ribosomal subunit protein uL3

OrganismNot specified

UniProt Q2FEN9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL3_STAA3
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain D； PDBConstruct 1–220； UniProt 1–220

Large ribosomal subunit protein uL4

OrganismNot specified

UniProt Q2FEP0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL4_STAA3
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain E； PDBConstruct 1–207； UniProt 1–207

Large ribosomal subunit protein uL5

OrganismNot specified

UniProt Q2FEQ1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL5_STAA3
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain F； PDBConstruct 1–179； UniProt 1–179

Large ribosomal subunit protein uL6

OrganismNot specified

UniProt Q2FEQ4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL6_STAA3
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain G； PDBConstruct 1–178； UniProt 1–178

Large ribosomal subunit protein uL13

OrganismNot specified

UniProt Q2FES1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL13_STAA3
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain H； PDBConstruct 1–145； UniProt 1–145

Large ribosomal subunit protein uL14

OrganismNot specified

UniProt Q2FEP9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL14_STAA3
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain I； PDBConstruct 1–122； UniProt 1–122

Large ribosomal subunit protein uL15

OrganismNot specified

UniProt Q2FEQ8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL15_STAA3
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain J； PDBConstruct 1–146； UniProt 1–146

Large ribosomal subunit protein uL16

OrganismNot specified

UniProt Q2FEP6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL16_STAA3
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain K； PDBConstruct 1–144； UniProt 1–144

Large ribosomal subunit protein uL18

OrganismNot specified

UniProt Q2FEQ5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL18_STAA3
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain M； PDBConstruct 1–119； UniProt 1–119

Large ribosomal subunit protein bL19

OrganismNot specified

UniProt Q2FHJ7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL19_STAA3
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain N； PDBConstruct 1–116； UniProt 1–116

Large ribosomal subunit protein bL20

OrganismNot specified

UniProt Q2FG58

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL20_STAA3
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain O； PDBConstruct 1–118； UniProt 1–118

Large ribosomal subunit protein bL21

OrganismNot specified

UniProt Q2FG80

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL21_STAA3
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain P； PDBConstruct 1–102； UniProt 1–102

Large ribosomal subunit protein uL22

OrganismNot specified

UniProt Q2FEP4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL22_STAA3
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain Q； PDBConstruct 1–117； UniProt 1–117

Large ribosomal subunit protein uL23

OrganismNot specified

UniProt Q2FEP1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL23_STAA3
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain R； PDBConstruct 1–91； UniProt 1–91

Large ribosomal subunit protein uL24

OrganismNot specified

UniProt Q2FEQ0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL24_STAA3
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain S； PDBConstruct 1–105； UniProt 1–105

50S ribosomal protein L25

OrganismNot specified

UniProt Q2FJE0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL25_STAA3
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain T； PDBConstruct 1–217； UniProt 1–217

Large ribosomal subunit protein bL27

OrganismNot specified

UniProt Q2FG82

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL27_STAA3
Isoform	—
PDB entities	25
Chains and sequence ranges	Author chain U； PDBConstruct 1–94； UniProt 1–94

Large ribosomal subunit protein bL28

OrganismNot specified

UniProt Q2FHL4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL28_STAA3
Isoform	—
PDB entities	26
Chains and sequence ranges	Author chain V； PDBConstruct 1–62； UniProt 1–62

Large ribosomal subunit protein uL29

OrganismNot specified

UniProt A0A0H2XHC7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A0H2XHC7_STAA3
Isoform	—
PDB entities	27
Chains and sequence ranges	Author chain W； PDBConstruct 1–73； UniProt 1–73

Large ribosomal subunit protein uL30

OrganismNot specified

UniProt Q2FEQ7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein bL32 × 1 （Q2FHV3） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL30_STAA3
Isoform	—
PDB entities	28
Chains and sequence ranges	Author chain X； PDBConstruct 1–59； UniProt 1–59

Large ribosomal subunit protein bL32

OrganismNot specified

UniProt Q2FHV3

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 27 RNA 4	Large ribosomal subunit protein bL33A × 1 （Q2FH98） Large ribosomal subunit protein bL34 × 1 （Q2FDE6） Large ribosomal subunit protein bL35 × 1 （Q2FG57） Large ribosomal subunit protein bL36 × 1 （Q2FER2） Large ribosomal subunit protein bL17 × 1 （Q2FER6） 23S rRNA × 1 5S rRNA × 1 Large ribosomal subunit protein uL2 × 1 （Q2FEP2） Large ribosomal subunit protein uL3 × 1 （Q2FEN9） Large ribosomal subunit protein uL4 × 1 （Q2FEP0） Large ribosomal subunit protein uL5 × 1 （Q2FEQ1） Large ribosomal subunit protein uL6 × 1 （Q2FEQ4） Large ribosomal subunit protein uL13 × 1 （Q2FES1） Large ribosomal subunit protein uL14 × 1 （Q2FEP9） Large ribosomal subunit protein uL15 × 1 （Q2FEQ8） Large ribosomal subunit protein uL16 × 1 （Q2FEP6） Large ribosomal subunit protein uL18 × 1 （Q2FEQ5） Large ribosomal subunit protein bL19 × 1 （Q2FHJ7） Large ribosomal subunit protein bL20 × 1 （Q2FG58） Large ribosomal subunit protein bL21 × 1 （Q2FG80） Large ribosomal subunit protein uL22 × 1 （Q2FEP4） Large ribosomal subunit protein uL23 × 1 （Q2FEP1） Large ribosomal subunit protein uL24 × 1 （Q2FEQ0） 50S ribosomal protein L25 × 1 （Q2FJE0） Large ribosomal subunit protein bL27 × 1 （Q2FG82） Large ribosomal subunit protein bL28 × 1 （Q2FHL4） Large ribosomal subunit protein uL29 × 1 （A0A0H2XHC7） Large ribosomal subunit protein uL30 × 1 （Q2FEQ7） P_site tRNA × 1 E_site tRNA × 1 ZINC ION × 3 MAGNESIUM ION × 231 ;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ; × 1 POTASSIUM ION × 12 water × 11	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL32_STAA3
Isoform	—
PDB entities	29
Chains and sequence ranges	Author chain Z； PDBConstruct 1–57； UniProt 1–57

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	9qeh
Deposition date deposition_date	2025-03-10
Structure title title	Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin
Keywords keywords	RIBOSOME; RIBOSOME
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9qeh__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9qeh__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

9qeh__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	66.47 Å
Rg (electron density)	66.94 Å
Total Rg	66.88 Å
Atom count	81610
Residues	5783
Excluded volume	1235300 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`9qeh__assembly_1__model_1`	31-meric （31）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (36)

Entity 1 Entity 1 polymer

Description description	Large ribosomal subunit protein bL33A
Molecular weight formula_weight	6305.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	1
Atom count atom_count	82317

MFNVRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK

Entity 2 Entity 2 polymer

Description description	Large ribosomal subunit protein bL34
Molecular weight formula_weight	5454.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	2

MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

Entity 3 Entity 3 polymer

Description description	Large ribosomal subunit protein bL35
Molecular weight formula_weight	7722.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	3

MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK

Entity 4 Entity 4 polymer

Description description	Large ribosomal subunit protein bL36
Molecular weight formula_weight	4318.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	4

MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG

Entity 5 Entity 5 polymer

Description description	Large ribosomal subunit protein bL17
Molecular weight formula_weight	13771.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

Entity 6 Entity 6 polymer

Description description	23S rRNA
Molecular weight formula_weight	946850.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	A

GAUUAAGUUAUUAAGGGCGCACGGUGGAUGCCUUGGCACUAGAAGCCGAUGAAGGACGUUACUAACGACGAUAUGCUUUGGGGAGCUGUAAGUAAGCUUUGAUCCAGAGAUUUCCGAAUGGGGAAACCCAGCAUGAGUUAUGUCAUGUUAUCGAUAUGUGAAUACAUAGCAUAUCAGAAGGCACACCCGGAGAACUGAAACAUCUUAGUACCCGGAGGAAGAGAAAGAAAAUUCGAUUCCCUUAGUAGCGGCGAGCGAAACGGGAAGAGCCCAAACCAACAAGCUUGCUUGUUGGGGUUGUAGGACACUCUGUACGGAGUUACAAAGGACGACAUUAGACGAAUCAUCUGGAAAGAUGAAUCAAAGAAGGUAAUAAUCCUGUAGUCGAAAAUGUUGUCUCUCUUGAGUGGAUCCUGAGUACGACGGAGCACGUGAAAUUCCGUCGGAAUCUGGGAGGACCAUCUCCUAAGGCUAAAUACUCUCUAGUGACCGAUAGUGAACCAGUACCGUGAGGGAAAGGUGAAAAGCACCCCGGAAGGGGAGUGAAAUAGAACCUGAAACCGUGUGCUUACAAGUAGUCAGAGCCCGUUAAUGGGUGAUGGCGUGCCUUUUGUAGAAUGAACCGGCGAGUUACGAUUUGAUGCAAGGUUAAGCAGUAAAUGUGGAGCCGUAGCGAAAGCGAGUCUGAAUAGGGCGUUUAGUAUUUGGUCGUAGACCCGAAACCAGGUGAUCUACCCUUGGUCAGGUUGAAGUUCAGGUAACACUGAAUGGAGGACCGAACCGACUUACGUUGAAAAGUGAGCGGAUGAACUGAGGGUAGCGGAGAAAUUCCAAUCGAACCUGGAGAUAGCUGGUUCUCUCCGAAAUAGCUUUAGGGCUAGCCUCAAGUGAUGAUUAUUGGAGGUAGAGCACUGUUUGGACGAGGGGCCCCUCUCGGGUUACCGAAUUCAGACAAACUCCGAAUGCCAAUUAAUUUAACUUGGGAGUCAGAACAUGGGUGAUAAGGUCCGUGUUCGAAAGGGAAACAGCCCAGACCACCAGCUAAGGUCCCAAAAUAUAUGUUAAGUGGAAAAGGAUGUGGCGUUGCCCAGACAACUAGGAUGUUGGCUUAGAAGCAGCCAUCAUUUAAAGAGUGCGUAAUAGCUCACUAGUCGAGUGACACUGCGCCGAAAAUGUACCGGGGCUAAACAUAUUACCGAAGCUGUGGAUUGUCCUUUGGACAAUGGUAGGAGAGCGUUCUAAGGGCGUUGAAGCAUGAUCGUAAGGACAUGUGGAGCGCUUAGAAGUGAGAAUGCCGGUGUGAGUAGCGAAAGACGGGUGAGAAUCCCGUCCACCGAUUGACUAAGGUUUCCAGAGGAAGGCUCGUCCGCUCUGGGUUAGUCGGGUCCUAAGCUGAGGCCGACAGGCGUAGGCGAUGGAUAACAGGUUGAUAUUCCUGUACCACCUAUAAUCGUUUUAAUCGAUGGGGGGACGCAGUAGGAUAGGCGAAGCGUGCGAUUGGAUUGCACGUCUAAGCAGUAAGGCUGAGUAUUAGGCAAAUCCGGUACUCGUUAAGGCUGAGCUGUGAUGGGGAGAAGACAUUGAGUCUUCGAGUCGUUGAUUUCACACUGCCGAGAAAAGCCUCUAGAUAGAAAAUAGGUGCCCGUACCGCAAACCGACACAGGUAGUCAAGAUGAGAAUUCUAAGGUGAGCGAGCGAACUCUCGUUAAGGAACUCGGCAAAAUGACCCCGUAACUUCGGGAGAAGGGGUGCUCUUUAGGGUUAACGCCCAGAAGAGCCGCAGUGAAUAGGCCCAAGCGACUGUUUAUCAAAAACACAGGUCUCUGCUAAACCGUAAGGUGAUGUAUAGGGGCUGACGCCUGCCCGGUGCUGGAAGGUUAAGAGGAGUGGUUAGCUUCUGCGAAGCUACGAAUCGAAGCCCCAGUAAACGGCGGCCGUAACUAUAACGGUCCUAAGGUAGCGAAAUUCCUUGUCGGGUAAGUUCCGACCCGCACGAAAGGCGUAACGAUUUGGGCACUGUCUCAACGAGAGACUCGGUGAAAUCAUAGUACCUGUGAAGAUGCAGGUUACCCGCGACAGGACGGAAAGACCCCGUGGAGCUUUACUGUAGCCUGAUAUUGAAAUUCGGCACAGCUUGUACAGGAUAGGUAGGAGCCUUUGAAACGUGAGCGCUAGCUUACGUGGAGGCGCUGGUGGGAUACUACCCUAGCUGUGUUGGCUUUCUAACCCGCACCACUUAUCGUGGUGGGAGACAGUGUCAGGCGGGCAGUUUGACUGGGGCGGUCGCCUCCUAAAAGGUAACGGAGGCGCUCAAAGGUUCCCUCAGAAUGGUUGGAAAUCAUUCAUAGAGUGUAAAGGCAUAAGGGAGCUUGACUGCGAGACCUACAAGUCGAGCAGGGUCGAAAGACGGACUUAGUGAUCCGGUGGUUCCGCAUGGAAGGGCCAUCGCUCAACGGAUAAAAGCUACCCCGGGGAUAACAGGCUUAUCUCCCCCAAGAGUUCACAUCGACGGGGAGGUUUGGCACCUCGAUGUCGGCUCAUCGCAUCCUGGGGCUGUAGUCGGUCCCAAGGGUUGGGCUGUUCGCCCAUUAAAGCGGUACGCGAGCUGGGUUCAGAACGUCGUGAGACAGUUCGGUCCCUAUCCGUCGUGGGCGUAGGAAAUUUGAGAGGAGCUGUCCUUAGUACGAGAGGACCGGGAUGGACAUACCUCUGGUGUACCAGUUGUCGUGCCAACGGCAUAGCUGGGUAGCUAUGUGUGGACGGGAUAAGUGCUGAAAGCAUCUAAGCAUGAAGCCCCCCUCAAGAUGAGAUUUCCCAACUUCGGUUAUAAGAUCCCUCAAAGAUGAUGAGGUUAAUAGGUUCGAGGUGGAAGCAUGGUGACAUGUGGAGCUGACGAAUACUAAUCGAUCGAAGACUUAAUCAA

Entity 7 Entity 7 polymer

Description description	5S rRNA
Molecular weight formula_weight	36974.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	B

UCUGGUGACUAUAGCAAGGAGGUCACACCUGUUCCCAUGCCGAACACAGAAGUUAAGCUCCUUAGCGUCGAUGGUAGUCGAACUUACGUUCCGCUAGAGUAGAACGUUGCCAGGC

Entity 8 Entity 8 polymer

Description description	Large ribosomal subunit protein uL2
Molecular weight formula_weight	30217.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKKK

Entity 9 Entity 9 polymer

Description description	Large ribosomal subunit protein uL3
Molecular weight formula_weight	23760.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK

Entity 10 Entity 10 polymer

Description description	Large ribosomal subunit protein uL4
Molecular weight formula_weight	22495.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG

Entity 11 Entity 11 polymer

Description description	Large ribosomal subunit protein uL5
Molecular weight formula_weight	20296.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAVQNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDKLISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTANTDEEARELLANFGMPFRK

Entity 12 Entity 12 polymer

Description description	Large ribosomal subunit protein uL6
Molecular weight formula_weight	19818.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEGKTGK

Entity 13 Entity 13 polymer

Description description	Large ribosomal subunit protein uL13
Molecular weight formula_weight	16359.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG

Entity 14 Entity 14 polymer

Description description	Large ribosomal subunit protein uL14
Molecular weight formula_weight	13157.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL

Entity 15 Entity 15 polymer

Description description	Large ribosomal subunit protein uL15
Molecular weight formula_weight	15628.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI

Entity 16 Entity 16 polymer

Description description	Large ribosomal subunit protein uL16
Molecular weight formula_weight	16274.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES

Entity 17 Entity 17 polymer

Description description	Large ribosomal subunit protein uL18
Molecular weight formula_weight	13124.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF

Entity 18 Entity 18 polymer

Description description	Large ribosomal subunit protein bL19
Molecular weight formula_weight	13392.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

Entity 19 Entity 19 polymer

Description description	Large ribosomal subunit protein bL20
Molecular weight formula_weight	13720.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDALK

Entity 20 Entity 20 polymer

Description description	Large ribosomal subunit protein bL21
Molecular weight formula_weight	11354.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA

Entity 21 Entity 21 polymer

Description description	Large ribosomal subunit protein uL22
Molecular weight formula_weight	12857.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDGKEEAKEA

Entity 22 Entity 22 polymer

Description description	Large ribosomal subunit protein uL23
Molecular weight formula_weight	10625.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN

Entity 23 Entity 23 polymer

Description description	Large ribosomal subunit protein uL24
Molecular weight formula_weight	11561.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN

Entity 24 Entity 24 polymer

Description description	50S ribosomal protein L25
Molecular weight formula_weight	23810.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

MASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIENDSAESVVTVVAPTEEPTEEEIEAMEGEQQTEEPEVVGESKEDEEKTEE

Entity 25 Entity 25 polymer

Description description	Large ribosomal subunit protein bL27
Molecular weight formula_weight	10334.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	U

MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE

Entity 26 Entity 26 polymer

Description description	Large ribosomal subunit protein bL28
Molecular weight formula_weight	6995.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	V

MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV

Entity 27 Entity 27 polymer

Description description	Large ribosomal subunit protein uL29
Molecular weight formula_weight	8592.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

MVKQMKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ

Entity 28 Entity 28 polymer

Description description	Large ribosomal subunit protein uL30
Molecular weight formula_weight	6565.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	X

MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLVTVEEK

Entity 29 Entity 29 polymer

Description description	Large ribosomal subunit protein bL32
Molecular weight formula_weight	6500.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEVAAK

Entity 30 Entity 30 polymer

Description description	P_site tRNA
Molecular weight formula_weight	22969.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	8

CGCGGGAUGGAGCAGGAGCUCGUCGGGCUCAUAGGCCGAAGGCGGUGGUUCAAAUCCGCCUCCCGCAACCA

Entity 31 Entity 31 polymer

Description description	E_site tRNA
Molecular weight formula_weight	4170.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	11

GGCCGGGCCACCA

Entity 32 Entity 32 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	3

Entity 33 Entity 33 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	231

Entity 34 Entity 34 non-polymer

Description description	;(3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside ;
Molecular weight formula_weight	845.0 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 35 Entity 35 non-polymer

Description description	POTASSIUM ION
Molecular weight formula_weight	39.1 kDa
Source method src_method	syn
Copy count entity_count	12

Entity 36 Entity 36 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	665

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	2.08 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	263087

Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin

1. Protein Identity and Related Structures Protein Identity & Related Structures

Large ribosomal subunit protein bL33A

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL34

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL35

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL36

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein bL17

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL3

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL4

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL5

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Large ribosomal subunit protein uL6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer