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9qfc

Tankyrase 2 ARC4 in complex with a pyrrolone-based inhibitor

Method: X-RAY DIFFRACTION Dmax: 80.1 Å Quality: REASONABLE

SAXS Profile

SAXS profile for 9qfc

P(r) Distribution

P(r) distribution for 9qfc

1. Structure Basics

entry_id9qfc
deposition_date2025-03-11
last_revision2026-01-14
titleTankyrase 2 ARC4 in complex with a pyrrolone-based inhibitor
keywordsInhibitor, transferase, Tankyrase 2, TNKS2, PARP5, ARC4; TRANSFERASE
methodX-RAY DIFFRACTION

Download Data

2. SAXS Parameters (CRYSOL)

rg_guinier23.25
rg_electron22.55
i022904800.00
molecular_weight36754.0 kDa
excluded_volume46076 ų
envelope_volume54132 ų
shell_volume20864 ų
envelope_diameter80.4
shell_rg28.59
envelope_rg22.71
shape_rg22.57
total_rg23.25
total_atoms5151
n_residues320
n_harmonics20
q_range— – 0.5000 −1
n_points101
shell_typedirectional
solvent_density0.3340 e/ų
contrast_shell0.0300 e/ų
crysol_version4.1.3

3. P(r) Analysis (GNOM)

dmax80.1
rg_real23.34
rg_real_error0.58
i0_real2.2900e+07
i0_real_error2.9290e+05
rg_reciprocal23.32
i0_reciprocal22900000.0000
total_estimate0.6627
solution_quality REASONABLE a REASONABLE solution
n_peaks2
r_peak_primary23.4
skewness0.450
kurtosis-0.227
angular_range— – 0.3400 −1
current_alpha0.0000
highest_alpha8728000.0000
n_real_points66
gnom_version4.1.3
quality_criteria AN1: 0.000; Oscil: 0.805; Stabil: 1.000; Sysdev: 0.115; Positv: 1.000; Valcen: 0.887; Smooth: 0.964

4. Crystallography & Experiment

5. Entities & Polymer Info (5)

6. Citations (1)

7. Files & Curves (10)