Entity 1
polymer
| description | Serine/threonine-protein kinase PLK1 |
| formula_weight | 36546.4 kDa |
| ec_number | 2.7.11.21 |
| mutation | K225D, K226A |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | AAA,BBB |
| atom_count | 5177 |
GSGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSDAGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPL
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Trichoplusia ni |
Entity 2
non-polymer
| description | ;(2~{Z})-2-cyano-2-[3-ethyl-5-[(~{E})-[2-[methyl-(1-methylpiperidin-4-yl)amino]pyridin-4-yl]iminomethyl]-4-oxidanylidene-1,3-thiazol-2-ylidene]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide
; |
| formula_weight | 523.6 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 3
non-polymer
| description | SULFATE ION |
| formula_weight | 96.1 kDa |
| src_method | syn |
| entity_count | 6 |
Entity 4
non-polymer
| description | GLYCEROL |
| formula_weight | 92.1 kDa |
| src_method | syn |
| entity_count | 5 |
Entity 5
non-polymer
| description | CHLORIDE ION |
| formula_weight | 35.5 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 185 |
