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9r4x

13 protofilament P. falciparum paclitaxel stabilised GDP microtubule

Method: ELECTRON MICROSCOPY D_max: 98.7 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9r4x
deposition_date	2025-05-08
title	13 protofilament P. falciparum paclitaxel stabilised GDP microtubule
keywords	Malaria, parasite, cytoskeleton, microtubule, paclitaxel, STRUCTURAL PROTEIN; STRUCTURAL PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	29.71 Å
rg_electron	29.11 Å
i0	154672000.00
molecular_weight	96490.0 kDa
excluded_volume	119560 Å³
envelope_volume	141550 Å³
shell_volume	40035 Å³
envelope_diameter	106.0 Å
shell_rg	36.92 Å
envelope_rg	29.44 Å
shape_rg	29.13 Å
total_rg	29.71 Å
total_atoms	6762
n_residues	850
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	98.7 Å
rg_real	29.73 Å
rg_real_error	0.79 Å
i0_real	1.5470e+08
i0_real_error	2.5810e+06
rg_reciprocal	29.72 Å
i0_reciprocal	154700000.0000
total_estimate	0.8755
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	33.5 Å
skewness	0.424
kurtosis	-0.269
angular_range	— – 0.2650 Å⁻¹
current_alpha	0.0000
highest_alpha	53180000.0000
n_real_points	54
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.819; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.993; Smooth: 0.929

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4. Crystallography & Experiment

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5. Entities & Polymer Info (6)

Entity 1 polymer

description	Tubulin alpha chain
formula_weight	50348.8 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	6762

MREVISIHVGQAGIQVGNACWELFCLEHGIQPDGQMPSDKASRANDDAFNTFFSETGAGKHVPRCVFVDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEVIDVCLDRIRKLADNCTGLQGFLMFSAVGGGTGSGFGCLMLERLSVDYGKKSKLNFCCWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAIMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVVSAEKAYHEQLSVSEITNSAFEPANMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDQKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIESNEAEGEDEGYEADY

Entity 2 polymer

description	Tubulin beta chain
formula_weight	49797.8 kDa
src_method	nat
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGTYCGDSDLQLERVDVFYNEATGGRYVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDAVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKIREEYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCASDPRHGRYLTACAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPHNTKSSVCDIPPKGLKMAVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEEGDVEA

Entity 3 non-polymer

description	GUANOSINE-5'-TRIPHOSPHATE
formula_weight	523.2 kDa
src_method	syn
entity_count	1

Entity 4 non-polymer

description	MAGNESIUM ION
formula_weight	24.3 kDa
src_method	syn
entity_count	1

Entity 5 non-polymer

description	GUANOSINE-5'-DIPHOSPHATE
formula_weight	443.2 kDa
src_method	syn
entity_count	1

Entity 6 non-polymer

description	TAXOL
formula_weight	853.9 kDa
src_method	syn
entity_count	1

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.20 Å
resolution_method	—
num_particles	30442

fit	/app/data/saxs_computation/r4/9r4x/9r4x.fit
pddf	/app/data/pr_computation/r4/9r4x/9r4x.pr.out
profile	/app/data/saxs_computation/r4/9r4x/9r4x.dat

13 protofilament P. falciparum paclitaxel stabilised GDP microtubule

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (6)

Entity 1 polymer

Polymer

Entity 2 polymer

Polymer

Entity 3 non-polymer

Entity 4 non-polymer

Entity 5 non-polymer

Entity 6 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)