Investigating the binding mechanism of Interferon Regulatory Factor 4 to DNA in the context of Multiple Myeloma

entry_id	9toy
deposition_date	2025-12-17
last_revision	2026-03-11
title	Investigating the binding mechanism of Interferon Regulatory Factor 4 to DNA in the context of Multiple Myeloma
keywords	Transcription Factor, DNA BINDING PROTEIN; DNA BINDING PROTEIN
method	X-RAY DIFFRACTION

rg_guinier	30.03 Å
rg_electron	29.43 Å
i0	138654000.00
molecular_weight	77842.0 kDa
excluded_volume	90661 ų
envelope_volume	125480 ų
shell_volume	35335 ų
envelope_diameter	96.2 Å
shell_rg	37.05 Å
envelope_rg	28.78 Å
shape_rg	29.43 Å
total_rg	30.06 Å
total_atoms	9979
n_residues	531
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	92.2 Å
rg_real	29.89 Å
rg_real_error	0.54 Å
i0_real	1.3870e+08
i0_real_error	1.7920e+06
rg_reciprocal	29.96 Å
i0_reciprocal	138700000.0000
total_estimate	0.9081
solution_quality	EXCELLENT a EXCELLENT solution
n_peaks	2
r_peak_primary	41.8 Å
skewness	0.106
kurtosis	-0.584
angular_range	— – 0.2650 Å−1
current_alpha	0.0000
highest_alpha	13070000.0000
n_real_points	54
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.960; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.998; Smooth: 0.923

Unit Cell

length_a	55.512 Å
length_b	65.116 Å
length_c	70.694 Å
angle_alpha	89.86 °
angle_beta	75.32 °
angle_gamma	66.79 °
z_pdb	4

Symmetry

space_group	P 1
int_tables_number	1
crystal_system	—

Refinement

resolution	2.100 Å
resolution_low	59.556 Å
r_factor	—
r_work	0.2107
r_free	0.2578

Diffraction

temperature

100.0 K

Files (7)

• pr_distribution /app/data/pr_computation/to/9toy/pr_distribution.json
• pr_output /app/data/pr_computation/to/9toy/9toy.pr.out
• pr_plot /app/data/visualization/pr_computation/to/9toy/9toy_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/to/9toy/9toy.dat
• saxs_fit /app/data/saxs_computation/to/9toy/9toy.fit
• saxs_log /app/data/saxs_computation/to/9toy/9toy.log
• saxs_plot /app/data/visualization/saxs_computation/to/9toy/9toy_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/to/9toy/9toy.fit
pddf	/app/data/pr_computation/to/9toy/9toy.pr.out
profile	/app/data/saxs_computation/to/9toy/9toy.dat