9u4l
Fibril structure of human alphaA-crystallin with pathogenic mutation R116C
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9u4l |
| deposition_date | 2025-03-19 |
| last_revision | 2025-08-20 |
| title | Fibril structure of human alphaA-crystallin with pathogenic mutation R116C |
| keywords | crystallin, amyloid, cryo-EM, cataract, PROTEIN FIBRIL; PROTEIN FIBRIL |
| method | ELECTRON MICROSCOPY |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 24.93 Å |
| rg_electron | 24.33 Å |
| i0 | 35067500.00 |
| molecular_weight | 48649.0 kDa |
| excluded_volume | 62123 ų |
| envelope_volume | 77742 ų |
| shell_volume | 27052 ų |
| envelope_diameter | 85.6 Å |
| shell_rg | 31.26 Å |
| envelope_rg | 24.35 Å |
| shape_rg | 24.26 Å |
| total_rg | 25.44 Å |
| total_atoms | 3462 |
| n_residues | 414 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 83.5 Å |
| rg_real | 24.92 Å |
| rg_real_error | 0.64 Å |
| i0_real | 3.5070e+07 |
| i0_real_error | 5.4790e+05 |
| rg_reciprocal | 24.92 Å |
| i0_reciprocal | 35070000.0000 |
| total_estimate | 0.8863 |
| solution_quality | GOOD a GOOD solution |
| n_peaks | 2 |
| r_peak_primary | 29.2 Å |
| skewness | 0.330 |
| kurtosis | -0.318 |
| angular_range | — – 0.3200 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 2416000.0000 |
| n_real_points | 64 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.848; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.976; Smooth: 0.996 |