9ubx

The atomic coordinates of the mouse CatSper trimer

Method: ELECTRON MICROSCOPY

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cation channel sperm-associated protein 1

Mus musculus

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSR1_MOUSE
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–251； UniProt 337–587 作者链 a； PDB构建体 1–251； UniProt 337–587 作者链 n； PDB构建体 1–251； UniProt 337–587

Cation channel sperm-associated protein 2

Mus musculus

UniProt A2ARP9

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSR2_MOUSE
Isoform	—
PDB实体	2
链与序列区间	作者链 B； PDB构建体 1–281； UniProt 94–374 作者链 b； PDB构建体 1–281； UniProt 94–374 作者链 o； PDB构建体 1–281； UniProt 94–374

Cation channel sperm-associated protein 3

Mus musculus

UniProt Q80W99

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	CTSR3_MOUSE
Isoform	—
PDB实体	3
链与序列区间	作者链 C； PDB构建体 1–278； UniProt 38–315 作者链 c； PDB构建体 1–278； UniProt 38–315 作者链 p； PDB构建体 1–278； UniProt 38–315

Cation channel sperm-associated protein 4

Mus musculus

UniProt Q8BVN3

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSR4_MOUSE
Isoform	—
PDB实体	4
链与序列区间	作者链 D； PDB构建体 1–250； UniProt 42–291 作者链 d； PDB构建体 1–250； UniProt 42–291 作者链 q； PDB构建体 1–250； UniProt 42–291

Cation channel sperm-associated auxiliary subunit beta

Mus musculus

UniProt A2RTF1

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSRB_MOUSE
Isoform	—
PDB实体	5
链与序列区间	作者链 E； PDB构建体 1–1065； UniProt 22–1086 作者链 e； PDB构建体 1–1065； UniProt 22–1086 作者链 r； PDB构建体 1–1065； UniProt 22–1086

Cation channel sperm-associated auxiliary subunit gamma 2

Mus musculus

UniProt C6KI89

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSG2_MOUSE
Isoform	—
PDB实体	6
链与序列区间	作者链 F； PDB构建体 1–1042； UniProt 44–1085 作者链 f； PDB构建体 1–1042； UniProt 44–1085 作者链 s； PDB构建体 1–1042； UniProt 44–1085

Cation channel sperm-associated auxiliary subunit delta

Mus musculus

UniProt E9Q9F6

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSRD_MOUSE
Isoform	—
PDB实体	7
链与序列区间	作者链 G； PDB构建体 1–733； UniProt 17–749 作者链 g； PDB构建体 1–733； UniProt 17–749 作者链 t； PDB构建体 1–733； UniProt 17–749

Cation channel sperm-associated auxiliary subunit epsilon

Mus musculus

UniProt P0DP43

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

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UniProt名称	CTSRE_MOUSE
Isoform	—
PDB实体	8
链与序列区间	作者链 H； PDB构建体 1–921； UniProt 50–970 作者链 h； PDB构建体 1–921； UniProt 50–970 作者链 u； PDB构建体 1–921； UniProt 50–970

EF-hand calcium-binding domain-containing protein 9

Mus musculus

UniProt Q9DAM2

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	EFCB9_MOUSE
Isoform	—
PDB实体	9
链与序列区间	作者链 I； PDB构建体 1–174； UniProt 1–174 作者链 Q； PDB构建体 1–174； UniProt 1–174 作者链 i； PDB构建体 1–174； UniProt 1–174

Cation channel sperm-associated auxiliary subunit TMEM249

Mus musculus

UniProt A0A2R8VHF7

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	TM249_MOUSE
Isoform	—
PDB实体	10
链与序列区间	作者链 J； PDB构建体 24–168； UniProt 1–145 作者链 j； PDB构建体 24–168； UniProt 1–145 作者链 w； PDB构建体 24–168； UniProt 1–145

Cation channel sperm-associated auxiliary subunit zeta

Mus musculus

UniProt Q9CQP8

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	CTSRZ_MOUSE
Isoform	—
PDB实体	11
链与序列区间	作者链 K； PDB构建体 1–149； UniProt 38–186 作者链 k； PDB构建体 1–149； UniProt 38–186 作者链 x； PDB构建体 1–149； UniProt 38–186

Solute carrier organic anion transporter family member 6C1

Mus musculus

UniProt Q8C0X7

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Cation channel sperm-associated auxiliary subunit TMEM262 × 3 （D3Z338） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	SO6C1_MOUSE
Isoform	—
PDB实体	12
链与序列区间	作者链 L； PDB构建体 1–610； UniProt 81–690 作者链 l； PDB构建体 1–610； UniProt 81–690 作者链 y； PDB构建体 1–610； UniProt 81–690

Cation channel sperm-associated auxiliary subunit TMEM262

Mus musculus

UniProt D3Z338

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 42 其他聚合物 30	Cation channel sperm-associated protein 1 × 3 （Q91ZR5） Cation channel sperm-associated protein 2 × 3 （A2ARP9） Cation channel sperm-associated protein 3 × 3 （Q80W99） Cation channel sperm-associated protein 4 × 3 （Q8BVN3） Cation channel sperm-associated auxiliary subunit beta × 3 （A2RTF1） Cation channel sperm-associated auxiliary subunit gamma 2 × 3 （C6KI89） Cation channel sperm-associated auxiliary subunit delta × 3 （E9Q9F6） Cation channel sperm-associated auxiliary subunit epsilon × 3 （P0DP43） EF-hand calcium-binding domain-containing protein 9 × 3 （Q9DAM2） Cation channel sperm-associated auxiliary subunit TMEM249 × 3 （A0A2R8VHF7） Cation channel sperm-associated auxiliary subunit zeta × 3 （Q9CQP8） Solute carrier organic anion transporter family member 6C1 × 3 （Q8C0X7） Unknown protein × 3 ;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 15 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 6 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 ;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 27 CHOLESTEROL × 3	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	TM262_MOUSE
Isoform	—
PDB实体	13
链与序列区间	作者链 M； PDB构建体 1–115； UniProt 1–115 作者链 m； PDB构建体 1–115； UniProt 1–115 作者链 z； PDB构建体 1–115； UniProt 1–115

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	9ubx
沉积日期 deposition_date	2025-04-03
结构标题 title	The atomic coordinates of the mouse CatSper trimer
关键词 keywords	sperm, hyperactivation, calcium channel, PROTEIN TRANSPORT; PROTEIN TRANSPORT
实验方法 method	ELECTRON MICROSCOPY

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

9ubx__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

9ubx__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

9ubx__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	0.00 Å
Rg（电子密度）	120.20 Å
总 Rg	120.10 Å
原子数	144816
残基数	18063
排除体积	2609200 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`9ubx__assembly_1__model_1`	42-meric （42）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (21)

实体 1 Entity 1 polymer

描述 description	Cation channel sperm-associated protein 1
分子量 formula_weight	29080.7 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,n,a
原子数 atom_count	144816

LLGLQQMILSLTQSLGFETFIFIVVCLNTVILVAQTFTELEIRGEWYFMVLDSIFLSIYVLEAVLKLIALGLEYFYDPWNNLDFFIMVMAVLDFVLLQINSLSYSFYNHSLFRILKVFKSMRALRAIRVLRRLSILTSLHEVAGTLSGSLPSITAILTLMFTCLFLFSVVLRALFQDSDPKRFQNIFTTLFTLFTMLTLDDWSLIYIDNRAQGAWYIIPILMIYIVIQYFIFLNLVIAVLVDNFQMALLKG

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 2 Entity 2 polymer

描述 description	Cation channel sperm-associated protein 2
分子量 formula_weight	33115.5 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	B,o,b

PLSLWAGWVLDSSVFSKFIISLIFLNTFVLMVEIELMESTNTALWPVKLALEVADWFILLSFIVEILLMWLASFSLFWKDAWNVFDFFVTLLSLLPELVVLLGVPAHSVWLQLLRVCRVLRSLKLFARFRQIKVILLALVRALKSMTFLLMLLLIFFYIFAVTGVYFFREYSRSTIEGLEYNMFFSDLLNSLVTVFILFTLDHWYAVLQDIWKVPESSRVFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRSELSEEMSHLEVQYKADMFKQQIIQRRQ

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 3 Entity 3 polymer

描述 description	Cation channel sperm-associated protein 3
分子量 formula_weight	32308.9 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	C,p,c

ECQAYFRKVIKSTFFQIVMITTVTTNSFLLVLGTNYDIQFEFFRTFEVSELFFVSVYVCEFLMKVYVDPITYWKDGYNILDVIILIILTIPYLLRKIKGNHSAYLHFADGIQSLRILKLISYSRGIRTLIIAVGETVYTVASVLTLLFLLMFVFAILGFCLFGVTDRGDLENWGNLASAFFTLFSLATVDGWTDLQEELDKRKFTVSRAFTILFILLASFIFLNMFVGVMIMHTEDSMKKFERDLTLERNLAIMEEKQIILKRQQEEVNRLMNTQKSG

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 4 Entity 4 polymer

描述 description	Cation channel sperm-associated protein 4
分子量 formula_weight	28880.4 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	D,q,d

DVMEKKDAWDVQEFITQMYIKQLLRHPAFQLLLAFLLLSNAITIALRTNSYLGQKHYELFSTIDDIVLTILICEVLLGWLNGFWIFWKDGWNILNFAIVFILFMGFFIKQLDMVAITYPLRVLRLVHVCMAVEPLARIIKVILQSMPDLANVMALILFFMLVFSVFGVTLFGAFVPKHFQNMGVALYTLFICITQDGWLDIYTDFQMDEREYAMEVGGAIYFAVFITLGAFIGLNLFVVVVTTNLEQMMK

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 5 Entity 5 polymer

描述 description	Cation channel sperm-associated auxiliary subunit beta
分子量 formula_weight	121580.6 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	E,r,e

VIHNKGKERTYFSCSGEGILTGLHTIKLFLTMDNLKVRCFFRNENQSPSKEILGLFTSGGLAPNMIITNSTFYGGYYFKLTPFSNRLEWLIDIPRQNITVNTDIAAVEQWMIKITMHEGLNIYDTEGTLLDLVREPILQWNLGRVLTEMEVRDLYPEVNDIKVTKSPCANDVALIGFMMKPSSNGVFIGKTISGFWTYKECIWHDLTEIIYAELKDEHQGLTVIDLVLTNHFLVILTSLGLYVSSDLRYPTTSQIKLSRAEFCGFERVDYIRGNLWYNEKCFANRESFEVDYVTITFNRNRTLSESSSCFFSKEPFLHWLPCVFSTIKNEKSIPRVITFLIDQETDSGIYLFNVQDTKETYVTVAMLKDGKPSPRPKFPSFHFPSTFTLPLGMIFHPRSHFLYVYGSQIWVSMDGGNTFEMLCNLFSHHVTKTSNSFYTSDIVFIVEDGRILTTKAGLTTYSELGILKDAIFTLYYDQLGYIHKLTPENFDAGSKLLGHGNSGSIFGKRPDLGFEAILVPQYISTNEMYFFAHVPLTMPTNIQWKKRFKTIHLGKTIEFSKTGLANIKNVYMHKTEPVGFQTSIHTEIIVPFGIENSKDSPCLLSDLEITYSGKLYYTIKLLSKNPLHELKSTDVEKSVLIPGYSSFLIMNITDKWTASALATMPQAIKSNLKFLTGSWFLYNFGTAGGRKWSISTRQCNYWIQQDSLDFMSLNLVKYIDVGNTIDFQFKIIPKAMSTFPIPPVSMVVGNPGLVEVKTQGVFDLNENYYLDIHVSGRFFQKGSTSIALVLWEGSSKCYAITLLPTIKSSCSYLRTMHHTPGRHIPPEDWISGVHKDSQGFNMIKTLPINYRPPSHMGISIPLTDNFYHADPSKPIPRNQFHKSKETGKYKQCANVTSRAMCNCSEHQKFSHAVAFSDCKEKVHRFKFPVTQYPVVLEIFNERDKISAEPPYLVTMTEVNMRKNWQLKHNEPENVKKMKHYLEPLLKTPVYNPLGLNLTIQGSELFHFKVSVVPGVSFCELSEEFQIYVDEVPLPFPGHALIAVATSVVLGVLIFIAFVFQLRNIH

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 6 Entity 6 polymer

描述 description	Cation channel sperm-associated auxiliary subunit gamma 2
分子量 formula_weight	119864.4 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	F,f,s

HCTWLLVLNKFEKVGLHLSKDRFQDHEPIDTVAKVFQKLTDSPIDPSENYLSFPYYLQINFSCPGQNIEELARKGHLMGMKPMVQINYMYSVNFYRWEMENVQILMEAAPMRSTGYCPAEAMCVLNWYTPMPFKNGSVVSSVDIYTNGIGPFVSKKRFYVNMNGFLKRDASGKSLFAIGYESLVLKSSHFRLSKSRPLWYTVNHAPVFILGGFYDEKSILFSDSNFQDYVLLELSIDSCWVGSFYCPILGFSATIHDAIATESTLFIRQNQLVYYFTGTYITLFDKSHGSSRWVRVLPSECIKRLCPVYASGNGSEYVLALTTGKNEGYIHIGTITDGLVSFEMVPDGWSVCEKLPGKNCSIDWATYIADERNLLLLVKIDSGQFYLVNFNTEFKTLNILYKIPEFIPEAKELDFLVLLDTVTYTNTPMTPKGLFFNTLNNMLYIWGNFILQSYNREEFIFLADFPKESTIKYMVNSFKGQMAVVTENEEIWYFLEGGYDVYQVVPSQGWETYHNLQKMQKSSFHSEDESLVSLFFEDGKLFQLVYLFDVGKERLVKRLLPVGTLMEYNLPKPFTVVNQGNYQAISFTHTCPFKEIHLIDVPKKHHASRTESYVALPPLVSESLGFHNNNTLAVYQGLVYYLLWLHSKYDKPYADPVHDPTWRWWQHKTKDKDYFFYLFSNRLAAEGIYINMNAYQKLYNMSGDYGIPDLFFLDKGNWFTITVVLLSHQDTFTSSDSQGPTINVDKKLAIAVTIADPECLSVTVTQDVLLNRNAVINKIKVIDKKRCSEQGMIGRNIKKTSMMLKVLGAPGNCIQRTYLGGIIQGFKVVPIFIGCPPGKRLAFDVSYTIMHSEEINKHYFDCVIKDAEMPCFLFRDLFQPFFLVQDLVTGDSGSFLGSYVLKVVGGGRTLNTIRDYTEEEIFRYNSPLDTTNSLIWKTKVERTTEDKKFYIMSHESPGVEWLCLENSPCYDIIPQSIYPPEFFFKLLVSNRGVDNSTYCDYKLTFIVHIHGLPLSSKRTSFIVMVSTSFFIALVVFYILFCL

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 7 Entity 7 polymer

描述 description	Cation channel sperm-associated auxiliary subunit delta
分子量 formula_weight	82834.3 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	G,t,g

HTLCRVHTVRTGKVFKSNIQLQGDPLFYAFPNTFVLKNVCKADISVYLGQKVFLTIDNFESSLLPLTVPKSLAVGVPSITSAHFVSGSLVLFVISGKGYSYDYYENTWRKLEGISEPVSHISGDVCCFKGSFCLELSNNLFAYLRGGQIPGTNIYFSDNGGFSFQLMNTDKLSHLTGTLGGIFHLHSMSQVGVLMVENNLGTFHYMEYPLNHSMGIAFSYKNLLEVIMKPYQRGFMVLWNQKSILVSSNSGQIVEHVRLIDQKIFTDLDVEHANINIYSVASNAYELAFLVAEDHLYYGSQSYMGTYVIKLPHQPLWSTHTSIYFEDIGILQVLTPVADPHFAAYDFDKCTVNVQSSLMDEKLALQPCNVELLESTMINTMFTIDMNSKLKLSALMIPRKGENPTPLVMVSNPHALGFKANLNEFGNTFDGNSKYKLDIELKQQHHWGNSDFNFTASIKRHAISSVTVDIADKTLSCVDLKPLSTLISVGCDMTKKIVVQNKISACTMGILNPVQLQKNYTYTIEKEAYDPINHNGEAQDDLIVFYEYKDLGCPRLVYYDKPWKPVVELWKNGIVEEIMNAEYVISEINGLVTYSYSLTAATANCRSQPQNWSTFESDIENEEPFLWNRENYVSCHEDNKDNPLLWPNVEYQVLGGQTNNKIIFGQRNGIYTFHLSVVDPYYSYCNLNTIFSVYVHGALPVTKFQPLLTILLMVTTTLLTAWLAYAIPKQLRS

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 8 Entity 8 polymer

描述 description	Cation channel sperm-associated auxiliary subunit epsilon
分子量 formula_weight	107004.0 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	H,u,h

LWRYYINSQDYSIFSTRSSIKLEYEGNSFVSWKIPESCKVENTTSPKTTLHCKRAGIHTIKPIAGNQEVERHLTVDNSYICYLWYFTVVDVYYNLSQIVTIWVYDPESASTEELIWTAKKPSLSSRVLTKQMNTLGQRPFIFTVEKRLTYHPGPLTSEGTWVIHLPMSSDDIAKVIRGNKVAFQDCFIANLYFMLTYPMTIISEPPGYEPLTVPPGSPLMLSWDTCISTFALLATDQETFQTNDSFQTWTRVRAPPGILSDAQRHSLRDVIIFDQGTLFLVDGTVYLRTEDEFTKLDESRGISETGILGFSKRRWCQIRYLYKLASKKSILIAWSKTTVYAGYATFRFVTLTDTAKLKDFLKLPQTDTLEVMSVEYLWHPLEAAVLLSHCSVCTTNTRNIRIVIYSAIFQTWTLQDFELQLPKEAILEFRFLYSAMPDIIMWDQHHVYYSYKNFTVVGTISTPSGETNLSSLSQGSKIHQVLTDRIGNVVVKMENNVMFYIKADITEAVILHTWVNTTAKTVVLFDKSFEVCILYYNENLDEKYQLQTQPYPLILELQSINKDLGDWCPYLAFQHNIHSQFYHMDKGESLTIWSQIVYPENRGLYIVVEHYGSSVMTWTQNLEYEIASGFCTKTMITRFFQTTNYELVDNYYQLQKENTGLMLLQFRPSEFSRTCLTAKPVFEIDVGCDSSKYIMVRGFNKSRCQRRDFSYVIDKELLRESLSDNLKVRYDVAKYGCPLTLELGQMFQPIVELYDENGFIKIVDANFILWEIHGRNDYTFNSTMEQNGCINEAQTWDSMIEENPDIPLDDVWGPQNYRPCFSYAIGKPGDLGQPYEILNYSNKNHIKWPMTYAGMYVYRLKILDPNYSFCNLTTIFAIESLGMIPRSSVYLVAALIFVLMLTFISILVLSYFWYLKIYRQF

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 9 Entity 9 polymer

描述 description	EF-hand calcium-binding domain-containing protein 9
分子量 formula_weight	20942.3 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	I,i,Q

MKLTPGCFLWYLYMDKIYCLLSLRNVKALMVYFHLLDVHHRNTLNDVLFFHFLQHVTNLNKSQIGMIFDLLDWTAVGEIGFDQFYVLICILLAHQDHLEDHFMYRHSRPVFELLDLDGEMNIGAANFQNYRFLFNIKKQELRDLFHDFDITGDRLLNYKEFKLYTIFCTDKSID

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 10 Entity 10 polymer

描述 description	Cation channel sperm-associated auxiliary subunit TMEM249
分子量 formula_weight	19898.6 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	J,w,j

MCWVMPPSVFVLEYYLDTLWKGTMLFIICLVFISCNVLREVKYQETWCFPAYGMVIGLWLMLSSIPQRRLVLNHTRGMYHFSIQGRTVCQGPMHLVYVRLALSSDAYGGRFFQLVLCGHKLEPLVLVQLSERYEQMEFLGRHLARKLNINYFDYLASSYRHVVRHWPL

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 11 Entity 11 polymer

描述 description	Cation channel sperm-associated auxiliary subunit zeta
分子量 formula_weight	17504.6 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	K,x,k

TANVSVSDVCEDFDEEGKSVRNRIRKYSQTISIRDSLNLEPEEIQQQARRELELCHGRSLEHGEDHEESETSLASSTSESLIFSLWKPHRTYWTEQQNRLPLPLMELMETEVLDILKKALITYRSTIGRNHFMTKELQGYIEGIRKRRN

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 12 Entity 12 polymer

描述 description	Solute carrier organic anion transporter family member 6C1
分子量 formula_weight	68349.7 kDa
突变 mutation	A224G
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	L,y,l

PIVLPFVQRFNNIDGFMTLYVAAVLIHGALFAVVDMTLNIYQVQFSLTRTEWYLMDFSDYIASFVVAIIIAHFGSKGNRTRWIAASCILMGLESMLFAFPFFTYEIIIPGRQSIELCMEENEKRNIICGNSVPNRSKCIYFHIGGQCIHGIAGMPIYILGITFIFDHIPTSSCGFYLAIGHSAYLIGYLLGMVGGLQNFQPPPKEKTVEIEPAKVYQLLQSGWWKTFLIIAAISFCVSFMMVCFPTSLPGAHKLRLAKRKEPPTIDRRLKDMKIQPHLKGFLHNIWHILKNPLMLTQAICKVSEYLTFNTSLYFLPHHLQTQFLITPGIASLLTGAFVLPGGIIGHFLGGLIVDRLEMTNKNKLKFTLVTTVVSVGLFLLIFFVECQTTTFAGINEDYDGYGQLGNLTADCNEYCDCTTSLYTSICGRDEKEYFSPCFAGCKATKVSQTEKTYYNCSCIKEGLAASDDEGQFIDAIAGTCDSDCLKLPLFFAFYFSATVFSNMCSIPVISIILQSVPANFTSLSLGVTYAIVKFVASVPAPLLFRLSSAIACIYWDNNRCGGKERCWIYNKNILVYEFMGIWMSSQLIIVLLNIYAIQIHDVVVHGEITE

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 13 Entity 13 polymer

描述 description	Cation channel sperm-associated auxiliary subunit TMEM262
分子量 formula_weight	13350.9 kDa
来源方法 src_method	man
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	M,z,m

MRWRDRIAVLCFPPGLMLTVAALILFFIHMGVFASDVHNFCVIHNYDHMSFRYTVVLIFSQVISIGWAAMGSLYAEMTGDKFLRCFALTILILNGAMFFNRLCLEFLAINYREER

来源 Source

来源生物 organism	Mus musculus
通用名 common_name	house mouse
NCBI 分类编号 ncbi_taxonomy_id	10090
宿主生物 host_organism	Mus musculus

实体 14 Entity 14 polymer

描述 description	Unknown protein
分子量 formula_weight	2401.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	3

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	N,P,O

XXXXXXXXXXXXXXXXXXXXXXXXXXXX

实体 15 Entity 15 branched

描述 description	;beta-D-mannopyranose-(1-2)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	1235.1 kDa
来源方法 src_method	man
拷贝数 entity_count	3

实体 16 Entity 16 branched

描述 description	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	586.5 kDa
来源方法 src_method	man
拷贝数 entity_count	15

实体 17 Entity 17 branched

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	424.4 kDa
来源方法 src_method	man
拷贝数 entity_count	6

实体 18 Entity 18 branched

描述 description	;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-[beta-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	1235.1 kDa
来源方法 src_method	man
拷贝数 entity_count	3

实体 19 Entity 19 branched

描述 description	;beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	910.8 kDa
来源方法 src_method	man
拷贝数 entity_count	3

实体 20 Entity 20 non-polymer

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	221.2 kDa
来源方法 src_method	man
拷贝数 entity_count	27

实体 21 Entity 21 non-polymer

描述 description	CHOLESTEROL
分子量 formula_weight	386.7 kDa
来源方法 src_method	syn
拷贝数 entity_count	3

▶

分辨率 resolution	6.80 Å
分辨率测定方法 resolution_method	—
颗粒数 num_particles	69708

The atomic coordinates of the mouse CatSper trimer

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cation channel sperm-associated protein 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated protein 2

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated protein 3

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated protein 4

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated auxiliary subunit beta

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated auxiliary subunit gamma 2

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated auxiliary subunit delta

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated auxiliary subunit epsilon

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

EF-hand calcium-binding domain-containing protein 9

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Cation channel sperm-associated auxiliary subunit TMEM249

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体