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9uev

Structure of the SFTSV Gn head protein in complex with Nb261 and Nb318

Method: ELECTRON MICROSCOPY D_max: 95.8 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9uev
deposition_date	2025-04-09
title	Structure of the SFTSV Gn head protein in complex with Nb261 and Nb318
keywords	SFTSV, nanobodies, complex, VIRAL PROTEIN/IMMUNE SYSTEM, VIRAL PROTEIN-IMMUNE SYSTEM complex; VIRAL PROTEIN/IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	28.85 Å
rg_electron	28.32 Å
i0	66281400.00
molecular_weight	61340.0 kDa
excluded_volume	75620 Å³
envelope_volume	94070 Å³
shell_volume	29206 Å³
envelope_diameter	102.4 Å
shell_rg	33.83 Å
envelope_rg	28.54 Å
shape_rg	28.29 Å
total_rg	28.92 Å
total_atoms	4297
n_residues	559
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	95.8 Å
rg_real	28.99 Å
rg_real_error	0.78 Å
i0_real	6.6280e+07
i0_real_error	1.0010e+06
rg_reciprocal	28.93 Å
i0_reciprocal	66280000.0000
total_estimate	0.8621
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	29.6 Å
skewness	0.477
kurtosis	-0.312
angular_range	— – 0.2750 Å⁻¹
current_alpha	0.0000
highest_alpha	16810000.0000
n_real_points	56
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.856; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.856; Smooth: 0.780

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	SFTSV Gn head
formula_weight	35366.1 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	A
atom_count	4297

DSGPIICAGPIHSNKSADIPHLLGYSEKICQIDRLIHVSSWLRNHSQFQGYVGQRGGRSQVSYYPAENSYSRWSGLLSPCDADWLGMLVVKKAKGSDMIVPGPSYKGKVFFERPTFDGYVGWGCGSGKSRTESGELCSSDSGTSSGLLPSNRVLWIGDVACQPMTPIPEETFLELKSFSQSEFPDICKIDGIVFNQCEGESLPQPFDVAWMDVGHSHKIIMREHKTKWVQESSSKDFVCYKEGTGPCSESEEKTCKTSGSCRGDMQFCKVAGCEHGEEASEAKCRCSLVHKPGEVVVSYGGMRVRPKCYGFSRMMATLEVN

Source

organism	Severe fever with thrombocytopenia syndrome virus
ncbi_taxonomy_id	1003835
host_organism	Homo

Entity 2 polymer

description	Nb261
formula_weight	12681.1 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	B

EVQLVESGGGLVQPGGSLRLSCAASGFTISNADMRWYRQAPGKERELVALLLSSLGGSTEYADSVKGRFTMFRDNARNTVYLQMDNLKAEDTAVYYCNVRWTDYWGQGTQVTVSS

Source

organism	Vicugna pacos
ncbi_taxonomy_id	30538
host_organism	Escherichia coli

Entity 3 polymer

description	Nb318
formula_weight	13363.8 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	C

EVQLVESGGGLVQAGGSLRLSCTASGLTFSSYAMGWFRQAPGKEREFVAAISWSGGDTYYEDSVKGRFTISRDNAANTVYLQMNSLKPEDTAVYYCNSGGIATMKLMDQYEYWGQGTQVTVSS

Source

organism	Vicugna pacos
ncbi_taxonomy_id	30538
host_organism	Escherichia coli

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.62 Å
resolution_method	—
num_particles	333824

fit	/app/data/saxs_computation/ue/9uev/9uev.fit
pddf	/app/data/pr_computation/ue/9uev/9uev.pr.out
profile	/app/data/saxs_computation/ue/9uev/9uev.dat

Structure of the SFTSV Gn head protein in complex with Nb261 and Nb318

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)