Cryo-EM structure of 5-HT2CR.

Method: ELECTRON MICROSCOPY D_max: 65.9 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9ugl
deposition_date	2025-04-12
title	Cryo-EM structure of 5-HT2CR.
keywords	5HTR, MEMBRANE PROTEIN; MEMBRANE PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	19.95 Å
rg_electron	19.07 Å
i0	23530000.00
molecular_weight	26505.0 kDa
excluded_volume	26580 Å³
envelope_volume	41985 Å³
shell_volume	18675 Å³
envelope_diameter	65.5 Å
shell_rg	25.24 Å
envelope_rg	19.50 Å
shape_rg	19.06 Å
total_rg	19.79 Å
total_atoms	2015
n_residues	268
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	65.9 Å
rg_real	19.94 Å
rg_real_error	0.37 Å
i0_real	2.3530e+07
i0_real_error	2.7560e+05
rg_reciprocal	19.94 Å
i0_reciprocal	23530000.0000
total_estimate	0.8803
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	23.2 Å
skewness	0.360
kurtosis	-0.310
angular_range	— – 0.4000 Å⁻¹
current_alpha	0.0000
highest_alpha	3465000.0000
n_real_points	72
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.834; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.978; Smooth: 0.959

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	triclinic

resolution	2.65 Å
resolution_method	—
num_particles	402295

description	5-hydroxytryptamine receptor 2C
formula_weight	45915.2 kDa
src_method	man
entity_count	1

type	polypeptide(L)
strand_id	A
atom_count	2015

Cryo-EM structure of 5-HT2CR.

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Spodoptera frugiperda

description	SB-242084
formula_weight	394.9 kDa
src_method	syn
entity_count	1

fit	/app/data/saxs_computation/ug/9ugl/9ugl.fit
pddf	/app/data/pr_computation/ug/9ugl/9ugl.pr.out
profile	/app/data/saxs_computation/ug/9ugl/9ugl.dat