Structural insight into DNA recognition by RRM1+2 domain of human ETR-3 protein

entry_id	9urh
deposition_date	2025-04-29
last_revision	2025-05-28
title	Structural insight into DNA recognition by RRM1+2 domain of human ETR-3 protein
keywords	Transcription Factor, Protein DNA complex, Human ETR3, Dual DNA and RNA binding, RRM, RNA BINDING PROTEIN; RNA BINDING PROTEIN
method	X-RAY DIFFRACTION

rg_guinier	24.50 Å
rg_electron	23.98 Å
i0	9067600.00
molecular_weight	21476.0 kDa
excluded_volume	26259 ų
envelope_volume	34848 ų
shell_volume	12625 ų
envelope_diameter	75.8 Å
shell_rg	29.59 Å
envelope_rg	23.52 Å
shape_rg	23.95 Å
total_rg	24.75 Å
total_atoms	1493
n_residues	182
n_harmonics	20
q_range	— – 0.5000 Å−1
n_points	101
shell_type	directional
solvent_density	0.3340 e/ų
contrast_shell	0.0300 e/ų
crysol_version	4.1.3

dmax	75.2 Å
rg_real	24.71 Å
rg_real_error	0.60 Å
i0_real	9.0680e+06
i0_real_error	1.2430e+05
rg_reciprocal	24.67 Å
i0_reciprocal	9067000.0000
total_estimate	0.7533
solution_quality	GOOD a GOOD solution
n_peaks	3
r_peak_primary	17.9 Å
skewness	0.250
kurtosis	-1.080
angular_range	— – 0.3250 Å−1
current_alpha	0.0000
highest_alpha	1209000.0000
n_real_points	64
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.473; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.434; Smooth: 0.938

Unit Cell

length_a	45.116 Å
length_b	70.770 Å
length_c	134.009 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	8

Symmetry

space_group	I 2 2 2
int_tables_number	23
crystal_system	—

Refinement

resolution	1.820 Å
resolution_low	37.770 Å
r_factor	0.1981
r_work	0.1970
r_free	0.2213

Diffraction

temperature

80.0 K

Files (7)

• pr_distribution /app/data/pr_computation/ur/9urh/pr_distribution.json
• pr_output /app/data/pr_computation/ur/9urh/9urh.pr.out
• pr_plot /app/data/visualization/pr_computation/ur/9urh/9urh_pr_distribution.png
• saxs_curve_dat /app/data/saxs_computation/ur/9urh/9urh.dat
• saxs_fit /app/data/saxs_computation/ur/9urh/9urh.fit
• saxs_log /app/data/saxs_computation/ur/9urh/9urh.log
• saxs_plot /app/data/visualization/saxs_computation/ur/9urh/9urh_saxs_profile.png

Curves (3)

fit	/app/data/saxs_computation/ur/9urh/9urh.fit
pddf	/app/data/pr_computation/ur/9urh/9urh.pr.out
profile	/app/data/saxs_computation/ur/9urh/9urh.dat