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9uyp

Cryo-EM structure of a class C GPCR (Class 3)

Method: ELECTRON MICROSCOPY D_max: 169.0 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9uyp
deposition_date	2025-05-15
title	Cryo-EM structure of a class C GPCR (Class 3)
keywords	GPCR, MEMBRANE PROTEIN; MEMBRANE PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	53.67 Å
rg_electron	55.74 Å
i0	398307000.00
molecular_weight	166900.0 kDa
excluded_volume	209530 Å³
envelope_volume	317010 Å³
shell_volume	51194 Å³
envelope_diameter	179.9 Å
shell_rg	50.29 Å
envelope_rg	55.52 Å
shape_rg	55.72 Å
total_rg	55.60 Å
total_atoms	11724
n_residues	1526
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	169.0 Å
rg_real	54.32 Å
rg_real_error	1.91 Å
i0_real	3.9830e+08
i0_real_error	8.3870e+06
rg_reciprocal	53.09 Å
i0_reciprocal	397600000.0000
total_estimate	0.7228
solution_quality	REASONABLE a REASONABLE solution
n_peaks	3
r_peak_primary	40.8 Å
skewness	0.521
kurtosis	-0.746
angular_range	— – 0.1450 Å⁻¹
current_alpha	0.0000
highest_alpha	27640000.0000
n_real_points	30
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.584; Stabil: 0.998; Sysdev: 1.000; Positv: 1.000; Valcen: 0.645; Smooth: 0.001

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

Entity 1 polymer

description	Metabotropic glutamate receptor 6
formula_weight	95539.3 kDa
src_method	man
entity_count	2

Polymer

type	polypeptide(L)
strand_id	A,B
atom_count	11724

GLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQLKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGHFLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHCEACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVATTTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHKFESRASTVPRARDPPVATLEVLFQ

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Spodoptera frugiperda

Entity 2 non-polymer

description	PHOSPHOSERINE
formula_weight	185.1 kDa
src_method	syn
entity_count	2

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.510 Å
resolution_low	— Å
r_factor	—
r_work	—
r_free	—

resolution	3.51 Å
resolution_method	—
num_particles	46689

fit	/app/data/saxs_computation/uy/9uyp/9uyp.fit
pddf	/app/data/pr_computation/uy/9uyp/9uyp.pr.out
profile	/app/data/saxs_computation/uy/9uyp/9uyp.dat

Cryo-EM structure of a class C GPCR (Class 3)

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

Refinement

EM 3D

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)