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9vca

Binding site between C-reactive protein and c2cc monoclonal antibody

Method: ELECTRON MICROSCOPY D_max: 78.4 Å Quality: GOOD

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9vca
deposition_date	2025-06-05
title	Binding site between C-reactive protein and c2cc monoclonal antibody
keywords	c-reactive protein, CRP, monoclonal antibody, immune complex, IgG, IMMUNE SYSTEM; IMMUNE SYSTEM
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	24.29 Å
rg_electron	23.40 Å
i0	37854500.00
molecular_weight	48027.0 kDa
excluded_volume	60268 Å³
envelope_volume	70589 Å³
shell_volume	25450 Å³
envelope_diameter	80.8 Å
shell_rg	30.18 Å
envelope_rg	23.72 Å
shape_rg	23.35 Å
total_rg	24.36 Å
total_atoms	6667
n_residues	433
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	78.4 Å
rg_real	24.30 Å
rg_real_error	0.44 Å
i0_real	3.7850e+07
i0_real_error	4.9050e+05
rg_reciprocal	24.30 Å
i0_reciprocal	37850000.0000
total_estimate	0.8967
solution_quality	GOOD a GOOD solution
n_peaks	2
r_peak_primary	27.4 Å
skewness	0.370
kurtosis	-0.383
angular_range	— – 0.3250 Å⁻¹
current_alpha	0.0000
highest_alpha	9252000.0000
n_real_points	64
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.894; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.975; Smooth: 0.994

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4. Crystallography & Experiment

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5. Entities & Polymer Info (3)

Entity 1 polymer

description	C-reactive protein
formula_weight	23068.0 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	E
atom_count	6667

QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP

Source

organism	Homo sapiens
common_name	human
ncbi_taxonomy_id	9606
host_organism	Homo sapiens

Entity 2 polymer

description	Monoclonal IgG antibody heavy chain fragment
formula_weight	49078.1 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	H

QVQLQQSGTELSKPGTGVKMSCKASGYTFISYWMHWVKQRPGQGLEWIGYINPSTDSTDYNQNFKDKATMTVDKSSTTAYMQLSTITSEDSAVYFCARSHYLSWDFDVWGAGTTVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVPEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMDTDGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGK

Source

organism	Mus musculus albula
ncbi_taxonomy_id	947985
host_organism	Mus musculus albula

Entity 3 polymer

description	Monoclonal IgG antibody light chain fragment
formula_weight	23957.4 kDa
src_method	man
entity_count	1

Polymer

type	polypeptide(L)
strand_id	L

DIVLTQSPASLAVSLGQRATISCRASQSVSTSGYSYIHWYQQKPGHPPKLLIKYASNLDSGVPARFSGSGSGTDFTLNIHPVEEEDAATYFCQHSWELPLTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC

Source

organism	Mus musculus albula
ncbi_taxonomy_id	947985
host_organism	Mus musculus albula

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	triclinic

resolution	2.40 Å
resolution_method	—
num_particles	1434575

fit	/app/data/saxs_computation/vc/9vca/9vca.fit
pddf	/app/data/pr_computation/vc/9vca/9vca.pr.out
profile	/app/data/saxs_computation/vc/9vca/9vca.dat

Binding site between C-reactive protein and c2cc monoclonal antibody

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (3)

Entity 1 polymer

Polymer

Source

Entity 2 polymer

Polymer

Source

Entity 3 polymer

Polymer

Source

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)