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9wri

Crystal structure of CtBP2 in complex with G9a

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

C-terminal-binding protein 2

Homo sapiens

UniProt P56545

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Histone-lysine N-methyltransferase EHMT2 × 2 （Q96KQ7） NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
2ome 2ome 2ome 2ome 4lcj 4lcj 4lcj 4lcj

8 assemblies

Homotetramer
6wkw

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
9wri

1 assemblies

View Construct and Data Evidence
UniProt name CTBP2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 3–336； UniProt 31–364 Author chain B； PDBConstruct 3–336； UniProt 31–364

Histone-lysine N-methyltransferase EHMT2

OrganismNot specified

UniProt Q96KQ7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 C-terminal-binding protein 2 × 4 （P56545） NICOTINAMIDE-ADENINE-DINUCLEOTIDE × 4 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2o8j 2o8j 2o8j 2o8j 3k5k 3k5k 5vse 5vse 6mm1 6mm1 6mm1 6mm1

14 assemblies; showing the first 12

Homodimer
3k5k 3rjw 4nvq 5ttf 5ttf 5tuy 5v9i 5v9i 5vsc 5vse 7btv 7buc

28 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3dm1 3dm1 3dm1 3dm1 3dm1 5jhn 5jin 5jiy 5jj0 5t0k 5t0k 5t0m

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name EHMT2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 1–13； UniProt 881–893

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9wri
Deposition date deposition_date2025-09-12
Last revision last_revision2026-01-21
Structure title titleCrystal structure of CtBP2 in complex with G9a
Keywords keywordsComplex, PROTEIN BINDING; PROTEIN BINDING
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9wri__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9wri__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9wri__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）35.26 Å
Rg (electron density)34.68 Å
Total Rg35.27 Å
Atom count10736
Residues1356
Excluded volume189710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9wri__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)