Entity 1
polymer
| description | GTPase NRas |
| formula_weight | 19410.9 kDa |
| ec_number | 3.6.5.2 |
| mutation | G12D, C118S |
| src_method | man |
| entity_count | 2 |
Polymer
| type | polypeptide(L) |
| strand_id | A,B |
| atom_count | 3132 |
GPMTEYKLVVVGADGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKSDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMK
Source
| organism | Homo sapiens |
| common_name | human |
| ncbi_taxonomy_id | 9606 |
| host_organism | Escherichia coli |
Entity 2
non-polymer
| description | GUANOSINE-5'-DIPHOSPHATE |
| formula_weight | 443.2 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 3
non-polymer
| description | MAGNESIUM ION |
| formula_weight | 24.3 kDa |
| src_method | syn |
| entity_count | 3 |
Entity 4
non-polymer
| description | ;(4P)-4-{3-[(1R,5S,6r)-3-azabicyclo[3.1.0]hexan-6-yl]-1-cyclopropyl-7-fluoro-4-(propan-2-yl)-1H-pyrazolo[4,3-c]pyridin-6-yl}-5-ethynyl-6-fluoronaphthalen-2-ol
; |
| formula_weight | 484.5 kDa |
| src_method | syn |
| entity_count | 2 |
Entity 5
non-polymer
| description | CITRIC ACID |
| formula_weight | 192.1 kDa |
| src_method | syn |
| entity_count | 1 |
Entity 6
water
| description | water |
| formula_weight | 18.0 kDa |
| src_method | nat |
| entity_count | 277 |
