Current Protein Identity:O43426
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1W80 Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170 Deposited 2004-09-14 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain P
1479–1490(12 aa)
Fragment:PEPTIDE CONTAINING WVXF MOTIF, RESIDUES 1479-1490
Chain Q
1460–1471(12 aa)
Fragment:PEPTIDE CONTAINING FXDXF MOTIF, RESIDUES 1460-1471
|
Not recorded | BEN BENZAMIDINE × 1 CO3 CARBONATE ION × 3 DTD DITHIANE DIOL × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;1.2M AMMONIUM SULFATE, 3% ISOPROPANOL, 0.05M SODIUM CITRATE, pH 6.50
|
Resolution 1.90 Å R-free 0.224 |
| 2DNR Solution structure of RNA binding domain in Synaptojanin 1 Deposited 2006-04-26 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
894–971(78 aa)
Fragment:RNA recognition motif
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7;298 K;Ionic strength (raw mmCIF value) 120mM;Pressure ambient
NMR sample composition
1.11mM 13C-15N PROTEIN, 20mM d-Tris-HCl(pH7.0), 100mM NaCl, 1mM d-DTT, 0.02% NaN3, 90% H2O, 10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2VJ0 Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex with an FXDNF peptide from amphiphysin1 and a WVXF peptide from synaptojanin P170 Deposited 2007-12-06 | Assembly 1 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain P
1479–1490(12 aa)
Fragment:PEPTIDE CONTAINING WVXF MOTIF, RESIDUES 1479-1490
|
Not recorded | BEN BENZAMIDINE × 1 DTD DITHIANE DIOL × 1 SO4 SULFATE ION × 3 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;1.2M AMMONIUM SULPHATE, 3% ISOPROPANOL AND 0.05M SODIUM CITRATE PH 6.5
|
Resolution 1.60 Å R-free 0.208 |
| 7A0V Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody Deposited 2020-08-11 | Assembly 1 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
528–873(346 aa)
Chain C
528–873(346 aa)
Chain E
528–873(346 aa)
|
Not recorded | PO4 PHOSPHATE ION × 3 MG MAGNESIUM ION × 3 GOL GLYCEROL × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5;293 K;15% PEG 4000, 0.1 M sodium citrate pH 5, 10% 2-propanol
|
Resolution 2.30 Å R-free 0.252 |
| 7A17 Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody Deposited 2020-08-12 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
528–873(346 aa)
|
Not recorded | IP9 (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate × 1 MG MAGNESIUM ION × 1 GOL GLYCEROL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;293 K;15% PEG 3350, 0.1 M sodium citrate pH 5.5, 13% ethanol
|
Resolution 2.73 Å R-free 0.257 |
| 7A17 Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody Deposited 2020-08-12 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
529–873(345 aa)
|
Not recorded | MG MAGNESIUM ION × 1 PO4 PHOSPHATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;293 K;15% PEG 3350, 0.1 M sodium citrate pH 5.5, 13% ethanol
|
Resolution 2.73 Å R-free 0.257 |
| 7A17 Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody Deposited 2020-08-12 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain E
529–873(345 aa)
|
Not recorded | PO4 PHOSPHATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 5.5;293 K;15% PEG 3350, 0.1 M sodium citrate pH 5.5, 13% ethanol
|
Resolution 2.73 Å R-free 0.257 |