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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：O75531 New Search
28PDB entries
30Biological assembly
66chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1CI4 THE CRYSTAL STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR (BAF) Deposited 1999-04-07 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；DIALYSIS OF PROTEIN AT 8.3 MG/ML IN 20MM TRIS HCL AT PH7.0, 10%(W/V) GLYCEROL, 150MM NACL, 10MM DTT, AND 0.1MM EDTA AGAINST 20MM IMIDAZOLE AT PH 6.5, 80MM NACL, AND 10MM DTT. DIALYSIS DONE AT ROOM TEMPERATURE.(ALL CONCENTRATIONS ARE IN MILLI-MOLAR)
Resolution 1.90 Å R-free 0.262
1QCK SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, REGULARIZED MEAN STRUCTURE PLUS 20 INDIVIDUAL SIMULATED ANNEALING STRUCTURES Deposited 1999-05-06 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；313 K
Resolution not provided
2BZF Structural basis for DNA bridging by barrier-to-autointegration factor (BAF) Deposited 2005-08-16 Assembly 1 Protein–DNA Homooligomer；Protein × 2 PDB declaration: hexameric（6） Consistent with all polymers
Chain A 1–89（89 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions pH 7.4；pH 7.40
Resolution 2.87 Å R-free 0.268
2EZX SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, REGULARIZED MEAN STRUCTURE Deposited 1998-07-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；313 K
Resolution not provided
2EZY SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF, NMR, ENSEMBLE OF 20 SIMULATED ANNEALING STRUCTURES Deposited 1998-07-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；313 K
Resolution not provided
2EZZ SOLUTION STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR BAF NMR, ENSEMBLE OF 20 SIMULATED ANNEALING STRUCTURES Deposited 1998-07-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；313 K
Resolution not provided
2ODG Complex of barrier-to-autointegration factor and LEM-domain of emerin Deposited 2006-12-22 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 1–89（89 aa） Fragment：RESIDUES 1-89
Chain B 1–89（89 aa） Fragment：RESIDUES 1-89
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6.5；303 K；Ionic strength (raw mmCIF value) 50 mM POTASSIUM PHOSPHATE 200 mM NACL
Resolution not provided
6GHD Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases Deposited 2018-05-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain D 2–89（88 aa）
Chain E 2–89（88 aa）
Not recorded SO4 SULFATE ION × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；25% PEG3.350, 20mM Tris-BispH5.5, 30mM NaCl, 0.2M NH4SO4
Resolution 2.10 Å R-free 0.247
6GHD Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases Deposited 2018-05-07 Assembly 2 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 2–89（88 aa）
Chain C 2–89（88 aa）
Not recorded SO4 SULFATE ION × 3 EDO 1,2-ETHANEDIOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；277 K；25% PEG3.350, 20mM Tris-BispH5.5, 30mM NaCl, 0.2M NH4SO4
Resolution 2.10 Å R-free 0.247
6UNT Barrier-to-autointegration factor soaked in DMSO: 1 of 14 in MSCS set Deposited 2019-10-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.75 Å R-free 0.223
6URE Barrier-to-autointegration factor Aqueous: 1 of 14 in MSCS set Deposited 2019-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.202
6URJ Barrier-to-autointegration factor soaked in Acetone: 1 of 14 in MSCS set Deposited 2019-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.192
6URK Barrier-to-autointegration factor soaked in Glycerol: 1 of 14 in MSCS set Deposited 2019-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.86 Å R-free 0.226
6URL Barrier-to-autointegration factor soaked in isopropanol: 1 of 14 in MSCS set Deposited 2019-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.72 Å R-free 0.201
6URN Barrier-to-autointegration factor t-butanol: 1 of 14 in MSCS set Deposited 2019-10-23 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.68 Å R-free 0.204
6URR Barrier-to-autointegration factor soaked in Dioxane: 1 of 14 in MSCS set Deposited 2019-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.80 Å R-free 0.230
6URZ Barrier-to-autointegration factor soaked in methanol: 1 of 14 in MSCS set Deposited 2019-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 MOH METHANOL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.201
6US0 Barrier-to-autointegration factor soaked in R,S,R-bisfuranol (RSR): 1 of 14 in MSCS set Deposited 2019-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.201
6US1 Barrier-to-autointegration factor soaked in isobutanol: 1 of 14 in MSCS set Deposited 2019-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.199
6US7 Barrier-to-autointegration factor soaked in TMAO: 1 of 14 in MSCS set Deposited 2019-10-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.198
6USB Barrier-to-autointegration factor soaked in urea: 1 of 14 in MSCS set Deposited 2019-10-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.68 Å R-free 0.210
6USD Barrier-to-autointegration factor soaked in ethanol: 1 of 14 in MSCS set Deposited 2019-10-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.202
6USI Barrier-to-autointegration factor soaked in 1,6-hexanediol: 1 of 14 in MSCS set Deposited 2019-10-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–89（89 aa）
Chain B 1–89（89 aa）
Not recorded EOH ETHANOL × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；277.15 K；80 mM Tris pH 8.5, 16% Ethanol, 10% PEG-1450
Resolution 1.65 Å R-free 0.208
7ABM X-ray structure of phosphorylated Barrier-to-autointegration factor (BAF) Deposited 2020-09-08 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 3–88（86 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) CS CESIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；pBAF was crystallized by the hanging drop method against 0.2 M sodium fluoride, 20% w/v PEG 3350
Resolution 3.00 Å R-free 0.326
7NDY Di-phosphorylated Barrier-to-Autointegration Factor (BAF) in complex with LEM domain of Emerin Deposited 2021-02-02 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 2–89（88 aa）
Chain B 2–89（88 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) EPE 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.5；277 K；Hepes Sodium salt 0.1 M pH 7.5 PEG 600 25% W/V
Resolution 1.44 Å R-free 0.225
7Z21 BAF A12T bound to the lamin A/C Ig-fold domain Deposited 2022-02-25 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 2–89（88 aa）
Chain C 2–89（88 aa）
Mutation：A12T Mutation：A12T CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；293 K；3 M ammonium sulfate 0.1 M bicine pH 9
Resolution 1.63 Å R-free 0.300
7Z21 BAF A12T bound to the lamin A/C Ig-fold domain Deposited 2022-02-25 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 2–89（88 aa）
Chain D 2–89（88 aa）
Mutation：A12T Mutation：A12T CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 9；293 K；3 M ammonium sulfate 0.1 M bicine pH 9
Resolution 1.63 Å R-free 0.300
9J8M Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (High mobility complex) Deposited 2024-08-21 Assembly 1 Protein–DNA Heteromer；Protein × 11 PDB declaration: tridecameric（13） Consistent with all polymers
Chain K 1–89（89 aa）
Chain L 1–89（89 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.82 Å
9J8N Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (Low mobility complex) Deposited 2024-08-21 Assembly 1 Protein–DNA Heteromer；Protein × 28 PDB declaration: 32-meric（32） Consistent with all polymers
Chain K 1–89（89 aa）
Chain L 1–89（89 aa）
Chain N 1–89（89 aa）
Chain O 1–89（89 aa）
Chain k 1–89（89 aa）
Chain l 1–89（89 aa）
Chain n 1–89（89 aa）
Chain o 1–89（89 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 7.14 Å
9J8O Cryo-EM structure of BAF-Lamin A/C IgF-H1-nucleosome complex Deposited 2024-08-21 Assembly 1 Protein–DNA Heteromer；Protein × 24 PDB declaration: 28-meric（28） Consistent with all polymers
Chain K 1–89（89 aa）
Chain L 1–89（89 aa）
Chain k 1–89（89 aa）
Chain l 1–89（89 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.5
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 4.05 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.