Current Protein Identity：O75962
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1NTY Crystal structure of the first DH/PH domain of Trio to 1.7 A Deposited 2003-01-30 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1225–1535（311 aa）
Fragment：N-terminal DH/PH domains, residues 1225-1535
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch Method.；pH 7.5；277 K；DTT, pH 7.5, Batch Method., temperature 277K
|
Resolution 1.70 Å R-free 0.214 |
| 2NZ8 N-terminal DHPH cassette of Trio in complex with nucleotide-free Rac1 Deposited 2006-11-22 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
1226–1535（310 aa）
Fragment：N-terminal DH/PH cassette (residues 1226-1535)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 6；291 K；100 mM sodium cacodylate pH 5.5 to 6.5, 14 to 18% (w/v) PEG 8000, and 300-500 mM calcium acetate, pH 6.0, VAPOR DIFFUSION, temperature 291K
|
Resolution 2.00 Å R-free 0.249 |
| 6D8Z Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio Deposited 2018-04-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
1960–2275（316 aa）
Fragment：UNP RESIDUES 1960-2275
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；14% PEG 3350, 100MM HEPES PH 7.5,
HANGING DROP, 293K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.65 Å R-free 0.266 |
| 6D8Z Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio Deposited 2018-04-27 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
1960–2275（316 aa）
Fragment：UNP RESIDUES 1960-2275
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；14% PEG 3350, 100MM HEPES PH 7.5,
HANGING DROP, 293K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.65 Å R-free 0.266 |
| 6D8Z Crystal Structure of the C-terminal Guanine Nucleotide Exchange Factor Module of Human Trio Deposited 2018-04-27 | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain C
1960–2275（316 aa）
Fragment：UNP RESIDUES 1960-2275
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；293 K；14% PEG 3350, 100MM HEPES PH 7.5,
HANGING DROP, 293K, VAPOR DIFFUSION, HANGING DROP
|
Resolution 2.65 Å R-free 0.266 |
| 7SJ4 Human Trio residues 1284-1959 in complex with Rac1 Deposited 2021-10-15 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1284–1959（676 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 8
cryo-EM vitrification conditions
Cryogen ETHANE；Blot force 10
|
Resolution 2.86 Å |