Current Protein Identity:O88273
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 4JPH Crystal structure of Protein Related to DAN and Cerberus (PRDC) Deposited 2013-03-19 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
22–168(147 aa)
Fragment:UNP residues 22-168
Chain B
22–168(147 aa)
Fragment:UNP residues 22-168
|
Not recorded | GOL GLYCEROL × 8 GSH Glutathione × 2 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;295 K;PEG3350, sodium citrate, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.25 Å R-free 0.222 |
| 4JPH Crystal structure of Protein Related to DAN and Cerberus (PRDC) Deposited 2013-03-19 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain C
22–168(147 aa)
Fragment:UNP residues 22-168
Chain D
22–168(147 aa)
Fragment:UNP residues 22-168
|
Not recorded | GOL GLYCEROL × 4 GSH Glutathione × 2 CIT CITRIC ACID × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 5.5;295 K;PEG3350, sodium citrate, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 2.25 Å R-free 0.222 |
| 5HK5 Structure of the Grem2-GDF5 Inhibitory Complex Deposited 2016-01-13 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain E
22–168(147 aa)
Chain F
22–168(147 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;HEPES, ammonium chloride, ethylammonium nitrate
|
Resolution 2.90 Å R-free 0.282 |
| 5HK5 Structure of the Grem2-GDF5 Inhibitory Complex Deposited 2016-01-13 | Assembly 2 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain E
22–168(147 aa)
Chain F
22–168(147 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;HEPES, ammonium chloride, ethylammonium nitrate
|
Resolution 2.90 Å R-free 0.282 |
| 5HK5 Structure of the Grem2-GDF5 Inhibitory Complex Deposited 2016-01-13 | Assembly 3 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain G
22–168(147 aa)
Chain H
22–168(147 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;HEPES, ammonium chloride, ethylammonium nitrate
|
Resolution 2.90 Å R-free 0.282 |
| 5HK5 Structure of the Grem2-GDF5 Inhibitory Complex Deposited 2016-01-13 | Assembly 4 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain G
22–168(147 aa)
Chain H
22–168(147 aa)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;293 K;HEPES, ammonium chloride, ethylammonium nitrate
|
Resolution 2.90 Å R-free 0.282 |