Current Protein Identity:O95931
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2K1B Solution NMR structure of the chromo domain of the chromobox protein homolog 7 Deposited 2008-02-25 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
7–62(56 aa)
Fragment:Chromo domain: Residues 7-62
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.4;298 K;Ionic strength (raw mmCIF value) 300;Pressure ambient
NMR sample composition
10 mM phosphate, 300 mM sodium chloride, 2 mM DTT, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 2L1B Solution NMR structure of the chromobox protein Cbx7 with H3K27me3 Deposited 2010-07-27 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
8–62(55 aa)
Fragment:UNP Residues 7-62
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 7.4;298 K;Ionic strength (raw mmCIF value) 300;Pressure ambient
NMR sample composition
0.5 mM [U-13C; U-15N] protein, 2.7 mM peptide, 10 mM sodium phosphate, 300 mM sodium chloride, 0.5 mM PMSF, 0.5 mM TCEP, 1 mM Benzamidine, 90% H2O/10% D2O | 90% H2O/10% D2O
|
Resolution not provided |
| 3GS2 Ring1B C-terminal domain/Cbx7 Cbox Complex Deposited 2009-03-26 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain B
219–248(30 aa)
Fragment:Cbox domain, residues 219-248
Chain D
219–248(30 aa)
Fragment:Cbox domain, residues 219-248
|
Not recorded | SO4 SULFATE ION × 2 ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;289 K;25% PEG MME 550, 0.1 M MES, 0.01 M zinc sulfate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.70 Å R-free 0.243 |
| 3GS2 Ring1B C-terminal domain/Cbx7 Cbox Complex Deposited 2009-03-26 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
219–248(30 aa)
Fragment:Cbox domain, residues 219-248
|
Not recorded | SO4 SULFATE ION × 2 ZN ZINC ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;289 K;25% PEG MME 550, 0.1 M MES, 0.01 M zinc sulfate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.70 Å R-free 0.243 |
| 3GS2 Ring1B C-terminal domain/Cbx7 Cbox Complex Deposited 2009-03-26 | Assembly 3 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain D
219–248(30 aa)
Fragment:Cbox domain, residues 219-248
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 6.5;289 K;25% PEG MME 550, 0.1 M MES, 0.01 M zinc sulfate, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
Resolution 1.70 Å R-free 0.243 |
| 4MN3 Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7) Deposited 2013-09-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
7–62(56 aa)
Fragment:protein
|
Not recorded | EDO 1,2-ETHANEDIOL × 3 MG MAGNESIUM ION × 1 P33 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7.5;298 K;40% ethylene glycol, 0.1M HEPES pH 7.5, 5% PEG 3000, VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 1.54 Å R-free 0.213 |
| 5EPJ Crystal Structure of chromodomain of CBX7 in complex with inhibitor UNC3866 Deposited 2015-11-11 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
7–62(56 aa)
|
Not recorded | UNX UNKNOWN LIGAND × 13 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;293 K;20% PEG 3350, 0.2 M ammonium formate
|
Resolution 1.60 Å R-free 0.260 |
| 6V2R Crystal Structure of chromodomain of CBX7 mutant V13A in complex with inhibitor UNC3866 Deposited 2019-11-25 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
7–62(56 aa)
Fragment:Chromodomain
|
Mutation:V13A | UNX UNKNOWN LIGAND × 17 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;293 K;1.5 M ammonium sulfate, 0.1 M bis-tris propane, pH 7
|
Resolution 1.60 Å R-free 0.235 |
| 8SII Crystal Structure of CBX7 with compound UNC4976 Deposited 2023-04-16 | Assembly 1 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
7–62(56 aa)
Fragment:chromodomain
|
Not recorded | SO4 SULFATE ION × 2 CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.5 M Ammonium Sulfate, 0.1 M BIS-Tris propane PH7.0
|
Resolution 1.37 Å R-free 0.223 |
| 8SII Crystal Structure of CBX7 with compound UNC4976 Deposited 2023-04-16 | Assembly 2 Protein heterocomplex Heteromer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain B
7–62(56 aa)
Fragment:chromodomain
|
Not recorded | SO4 SULFATE ION × 2 CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 7;291 K;2.5 M Ammonium Sulfate, 0.1 M BIS-Tris propane PH7.0
|
Resolution 1.37 Å R-free 0.223 |
| 9V9P Cryo-EM structure of the cPRC1-di-nucleosome (CBX7) complex Deposited 2025-06-01 | Assembly 1 Protein–DNA Heteromer;Protein × 22 PDB declaration: 24-meric(24) Consistent with all polymers |
Chain S
1–251(251 aa)
Chain Y
1–251(251 aa)
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY | mmCIF provides none of the parsed conditions | Resolution 3.40 Å |