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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P03472 New Search
48PDB entries
53Biological assembly
59chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1A14 COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 5 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE Deposited 1997-12-21 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain N 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 6.6；NC10 SCFV(5) AND N9 NA WERE MIXED TOGETHER (SCFV(5) IN FOUR-FOLD MOLAR EXCESS) WITH AND EQUAL VOLUME OF POTASSIUM PHOSPHATE BUFFER 1.7M PH6.6. THE DROP WAS EQUILIBRATED BY VAPOR DIFFUSION AGAINST PHOSPHATE BUFFER 1.3M PH6.8., vapor diffusion
Resolution 2.50 Å R-free 0.270
1BJI THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH THE GLAXO 6-CARBOXAMIDE SIALIC ACID ANALOGUE GR217029 Deposited 1997-12-03 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 DPC 5-ACETYLAMINO-4-AMINO-6-(PHENETHYL-PROPYL-CARBAMOYL)-5,6-DIHYDRO-4H-PYRAN-2-CARBOXYLIC ACID × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；1.9M PHOSPHATE(PH 5.9) THE GLAXO 6-CARBOXAMIDE COMPOUND GR217029 WAS SOAKED IN TERN N9 NEURAMININDASE CRYSTALS AT 5 MM FOR 24HR. THIS EXPERIMENT WAS CARRIED OUT TO DETERMINE THE BINDING MODE OF THE 6-CARBOXAMIDE HYDROPHOBIC GROUP. A NEW HYDROPHOBIC POCKET WAS DISCOVERED EARLIER WITH A METHYL, ETHYL GROUP ATTACHED TO THE AMIDE OF TH3E SIX-CARBOXAMIDE. THIS COMPOUND HAS A MUCH LARGER HYDROPHOBIC GROUP ATTACHED., pH 7.0
Resolution 2.00 Å
1INY A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES Deposited 1994-09-26 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 EQP (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol × 4 X-RAY DIFFRACTION
X-ray crystallization conditions NATIVE CRYSTALS SOAKED IN 10MM EPANA SOLUTION, PH 7.2.
Resolution 2.40 Å
1L7F Crystal structure of influenza virus neuraminidase in complex with BCX-1812 Deposited 2002-03-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：integral membrane protein, membrane stalk cleaved by pronase releasing fully active residues 82-468
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 BCZ 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID × 4 GOL GLYCEROL × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.9；293 K；phosphate, pH 5.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.80 Å R-free 0.187
1L7G Crystal structure of E119G mutant influenza virus neuraminidase in complex with BCX-1812 Deposited 2002-03-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：integral membrane protein, membrane stalk cleaved by pronase releasing fully active residues 82-468
Mutation：E119G NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 BCZ 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID × 4 GOL GLYCEROL × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.9；293 K；phosphate, pH 5.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.85 Å R-free 0.168
1L7H Crystal structure of R292K mutant influenza virus neuraminidase in complex with BCX-1812 Deposited 2002-03-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：integral membrane protein, membrane stalk cleaved by pronase releasing fully active residues 82-468
Mutation：R292K NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 12 BCZ 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID × 4 GOL GLYCEROL × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.9；293 K；phosphate, pH 5.9, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 1.85 Å R-free 0.177
1MWE THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH SIALIC ACID AT 4 DEGREES C REVEALING A SECOND SIALIC ACID BINDING SITE Deposited 1997-08-27 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 12 SIA N-acetyl-alpha-neuraminic acid × 8 CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.70 Å
1NCA REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX Deposited 1992-01-21 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain N 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NCA REFINED CRYSTAL STRUCTURE OF THE INFLUENZA VIRUS N9 NEURAMINIDASE-NC41 FAB COMPLEX Deposited 1992-01-21 Assembly 2 Other combination Heteromer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count
Chain N 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 16 CA CALCIUM ION × 8 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NCB CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE Deposited 1992-01-21 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain N 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NCB CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE Deposited 1992-01-21 Assembly 2 Other combination Heteromer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count
Chain N 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 8 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NCC CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE Deposited 1992-01-21 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain N 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NMC COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE Deposited 1997-12-21 Assembly 1 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain N 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.6；NC10 SCFV(15) AND N9 NA WERE MIXED TOGETHER (SCFV(15) IN SLIGHT MOLAR EXCESS) WITH AND EQUAL VOLUME OF POTASSIUM PHOSPHATE BUFFER 1.7M PH6.6. THE DROP WAS EQUILIBRATED BY VAPOUR DIFFUSION AGAINST PHOSPHATE BUFFER 1.3M PH6.8.
Resolution 2.50 Å R-free 0.260
1NMC COMPLEX BETWEEN NC10 ANTI-INFLUENZA VIRUS NEURAMINIDASE SINGLE CHAIN ANTIBODY WITH A 15 RESIDUE LINKER AND INFLUENZA VIRUS NEURAMINIDASE Deposited 1997-12-21 Assembly 2 Other combination Heteromer；Protein × 12 PDB declaration: dodecameric（12） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.6；NC10 SCFV(15) AND N9 NA WERE MIXED TOGETHER (SCFV(15) IN SLIGHT MOLAR EXCESS) WITH AND EQUAL VOLUME OF POTASSIUM PHOSPHATE BUFFER 1.7M PH6.6. THE DROP WAS EQUILIBRATED BY VAPOUR DIFFUSION AGAINST PHOSPHATE BUFFER 1.3M PH6.8.
Resolution 2.50 Å R-free 0.260
1NNA THREE-DIMENSIONAL STRUCTURE OF INFLUENZA A N9 NEURAMINIDASE AND ITS COMPLEX WITH THE INHIBITOR 2-DEOXY 2,3-DEHYDRO-N-ACETYL NEURAMINIC ACID Deposited 1993-03-08 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 84–470（387 aa）
Not recorded CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.50 Å
1NNB THREE-DIMENSIONAL STRUCTURE OF INFLUENZA A N9 NEURAMINIDASE AND ITS COMPLEX WITH THE INHIBITOR 2-DEOXY 2,3-DEHYDRO-N-ACETYL NEURAMINIC ACID Deposited 1993-03-08 Assembly 1 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 84–470（387 aa）
Not recorded CA CALCIUM ION × 4 DAN 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.80 Å
1NNC INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) COMPLEXED WITH 4-GUANIDINO-NEU5AC2EN INHIBITOR Deposited 1995-03-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 ZMR ZANAMIVIR × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 1.80 Å
1XOE N9 Tern influenza neuraminidase complexed with (2R,4R,5R)-5-(1-Acetylamino-3-methyl-butyl-pyrrolidine-2, 4-dicarobyxylic acid 4-methyl esterdase complexed with Deposited 2004-10-06 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 84–470（387 aa） Fragment：N9 tern Influenza Neuraminidase
Not recorded MAN alpha-D-mannopyranose × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ABX 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-4-(METHOXYCARBONYL)PROLINE × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.20 Å R-free 0.315
1XOE N9 Tern influenza neuraminidase complexed with (2R,4R,5R)-5-(1-Acetylamino-3-methyl-butyl-pyrrolidine-2, 4-dicarobyxylic acid 4-methyl esterdase complexed with Deposited 2004-10-06 Assembly 2 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 84–470（387 aa） Fragment：N9 tern Influenza Neuraminidase
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 ABX 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-4-(METHOXYCARBONYL)PROLINE × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.20 Å R-free 0.315
1XOG N9 Tern Influenza neuraminidase complexed with a 2,5-Disubstituted tetrahydrofuran-5-carboxylic acid Deposited 2004-10-06 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 84–470（387 aa） Fragment：N9 Tern neuraminidas
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 ABW 5-[1-(ACETYLAMINO)-3-METHYLBUTYL]-2,5-ANHYDRO-3,4-DIDEOXY-4-(METHOXYCARBONYL)PENTONIC ACID × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.80 Å R-free 0.297
2C4A Structure of Neuraminidase Subtype N9 Complexed with 30 MM Sialic Acid (NANA, NEU5AC), Crystal Soaked for 3 Hours at 291 K. Deposited 2005-10-17 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 83-470
Not recorded SIA N-acetyl-alpha-neuraminic acid × 8 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；PROTEIN WAS CRYSTALLISED FROM 1.9M POTASSIUM PHOSPHATE PH 6.8, THEN SOAKED FOR 3 HOURS IN 30 MM NEU5AC
Resolution 2.15 Å R-free 0.205
2C4L Structure of Neuraminidase Subtype N9 Complexed with 30 MM Sialic Acid (NANA, NEU5AC), Crystal Soaked for 24 Hours at 291 K and Finally Backsoaked for 30 Min in a Cryoprotectant Solution which did not contain NEU5AC Deposited 2005-10-20 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 83-470
Not recorded SIA N-acetyl-alpha-neuraminic acid × 8 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 20 BMA beta-D-mannopyranose × 20 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.8；PROTEIN WAS CRYSTALLISED FROM 1.9M POTASSIUM PHOSPHATE PH 6.8, THEN SOAKED FOR 24 HOURS IN 30 MM NEU5AC AND FINALLY BACKSOAKED FOR 30 MIN IN A CRYOPROTECTANT SOLUTION WHICH DID NOT CONTAIN NEU5AC
Resolution 2.15 Å R-free 0.196
2QWA THE X-RAY STRUCTURE OF A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.70 Å
2QWB THE X-RAY STRUCTURE OF A COMPLEX OF SIALIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 SIA N-acetyl-alpha-neuraminic acid × 8 CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 2.00 Å
2QWC THE X-RAY STRUCTURE OF A COMPLEX OF NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 DAN 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.60 Å
2QWD THE X-RAY STRUCTURE OF A COMPLEX OF 4-AMINO-NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 4AM 4-AMINO-2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 2.00 Å
2QWE THE X-RAY STRUCTURE OF A COMPLEX OF 4-GUANIDINO-NEU5AC2EN AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 ZMR ZANAMIVIR × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 2.00 Å
2QWF THE X-RAY STRUCTURE OF A COMPLEX OF N-ACETYL-4-GUANIDINO-6-METHYL(PROPYL)CARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 G20 5-N-acetyl-4-guanidino-6-methyl(propyl) carboxamide-4,5-dihydro-2H-pyran-2-carboxylic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.90 Å
2QWG THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-4-AMINO-6-DIETHYLCARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 G28 5-N-acetyl-4-amino-6-diethyl carboxamide-4,5-dihydro-2H-pyran-2-carboxylic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.80 Å
2QWH THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-5-AMINO-3-(1-ETHYLPROPOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Mutation：R292K (N2-TOKYO/67 NUMBERING) NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 G39 (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid × 4 CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.80 Å
2QWI THE X-RAY STRUCTURE OF A COMPLEX OF N-ACETYL-4-GUANIDINO-6-METHYL(PROPYL)CARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded MAN alpha-D-mannopyranose × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 G20 5-N-acetyl-4-guanidino-6-methyl(propyl) carboxamide-4,5-dihydro-2H-pyran-2-carboxylic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 2.00 Å
2QWJ THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-4-AMINO-6-DIETHYLCARBOXAMIDE-4,5-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID AND A DRUG RESISTANT VARIANT R292K OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 G28 5-N-acetyl-4-amino-6-diethyl carboxamide-4,5-dihydro-2H-pyran-2-carboxylic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 2.00 Å
2QWK THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-5-AMINO-3-(1-ETHYLPROPOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE Deposited 1998-04-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：RESIDUES 82 - 468
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 G39 (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid × 4 CA CALCIUM ION × 8 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.9；1.9M PHOSPHATE (PH 5.9)
Resolution 1.80 Å
3NN9 REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS Deposited 1991-03-28 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.30 Å
3W09 Influenza virus neuraminidase subtype N9 (TERN) complexed with 2,3-dif guanidino-neu5ac2en inhibitor Deposited 2012-10-25 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 GOL GLYCEROL × 28 ZGE 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-3-fluoro-D-glycero-D-galacto-non-2-enonic acid × 4 CA CALCIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.9；298 K；1.9M ammonium phosphate, pH 5.9, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 2.00 Å R-free 0.189
4DGR Influenza Subtype 9 Neuraminidase Benzoic Acid Inhibitor Complex Deposited 2012-01-26 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 82–470（389 aa） Fragment：neuraminidase
Not recorded BGC beta-D-glucopyranose × 12 GLC alpha-D-glucopyranose × 4 3LV 4-[2,2-bis(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(dipropylamino)methyl]benzoic acid × 4 PO4 PHOSPHATE ION × 4 CA CALCIUM ION × 8 K POTASSIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.9；298 K；1.9 M phosphate buffer, pH 6.9, VAPOR DIFFUSION, HANGING DROP, temperature 298K
Resolution 1.55 Å R-free 0.152
4NN9 REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS Deposited 1991-03-28 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.30 Å
4WEG influenza virus neuraminidase N9 in complex 2,3-difluorosialic acid Deposited 2014-09-10 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：UNP residues 83-470
Not recorded SFJ (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 DF4 (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate × 4 FSI 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.7；293 K；1.7M potassium phosphate
Resolution 2.10 Å R-free 0.201
5NN9 REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS Deposited 1991-03-28 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.30 Å
5W26 INFLUENZA VIRUS NEURAMINIDASE N9 IN COMPLEX WITH 4-DEOXYGENATED 2,3-DIFLUORO-N-ACETYLNEURAMINIC ACID Deposited 2017-06-05 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：UNP RESIDUES 82-469
Not recorded 9SG (2R,3R,5R,6R)-5-acetamido-2,3-bis(fluoranyl)-6-[(1R,2R)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 9WM (2~{R},3~{R},5~{R})-3-acetamido-5-fluoranyl-2-[(1~{R},2~{R})-1,2,3-tris(oxidanyl)propyl]-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid × 4 9VP 5-acetamido-2,6-anhydro-3,4,5-trideoxy-3-fluoro-D-erythro-L-gluco-nononic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.7；298 K；1.7M POTASSIUM PHOSPHATE
Resolution 1.90 Å R-free 0.177
5W2U INFLUENZA VIRUS NEURAMINIDASE N9 IN COMPLEX WITH 7-DEOXYGENATED 2,3-DIFLUORO-N-ACETYLNEURAMINIC ACID Deposited 2017-06-06 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：UNP RESIDUES 82-469
Not recorded 9SM (2R,3R,4R,5R,6S)-5-acetamido-6-[(2S)-2,3-bis(oxidanyl)propyl]-2,3-bis(fluoranyl)-4-oxidanyl-oxane-2-carboxylic acid × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 9S4 (2~{S},3~{R},4~{R},5~{R})-3-acetamido-2-[(2~{S})-2,3-bis(oxidanyl)propyl]-5-fluoranyl-4-oxidanyl-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid × 4 9SJ 5-acetamido-2,6-anhydro-3,5,7-trideoxy-3-fluoro-D-threo-L-galacto-nononic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.7；289 K；1.7M POTASSIUM PHOSPHATE
Resolution 2.00 Å R-free 0.187
5W2W INFLUENZA VIRUS NEURAMINIDASE N9 IN COMPLEX WITH 8-DEOXYGENATED 2,3-DIFLUORO-N-ACETYLNEURAMINIC ACID Deposited 2017-06-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：UNP RESIDUES 82-469
Not recorded 9SP (2R,3R,4R,5R,6R)-5-acetamido-6-[(1R)-1,3-bis(oxidanyl)propyl]-2,3-bis(fluoranyl)-4-oxidanyl-oxane-2-carboxylic acid × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 9SD (2~{R},3~{R},4~{R},5~{R})-3-acetamido-2-[(1~{R})-1,3-bis(oxidanyl)propyl]-5-fluoranyl-4-oxidanyl-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid × 4 9S7 5-acetamido-2,6-anhydro-3,5,8-trideoxy-3-fluoro-D-threo-L-galacto-nononic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.7；298 K；1.7M POTASSIUM PHOSPHATE
Resolution 1.85 Å R-free 0.171
5W2Y INFLUENZA VIRUS NEURAMINIDASE N9 IN COMPLEX WITH 9-DEOXYGENATED 2,3-DIFLUORO-N-ACETYLNEURAMINIC ACID Deposited 2017-06-07 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa） Fragment：UNP RESIDUES 82-469
Not recorded 9T7 (2R,3R,4R,5R,6R)-5-acetamido-6-[(1R,2R)-1,2-bis(oxidanyl)propyl]-2,3-bis(fluoranyl)-4-oxidanyl-oxane-2-carboxylic acid × 4 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 4 9TM (2~{R},3~{R},4~{R},5~{R})-3-acetamido-2-[(1~{R},2~{R})-1,2-bis(oxidanyl)propyl]-5-fluoranyl-4-oxidanyl-2,3,4,5-tetrahydropyran-1-ium-6-carboxylic acid × 4 9T1 5-acetamido-2,6-anhydro-3,5,9-trideoxy-3-fluoro-D-erythro-L-gluco-non-4-ulosonic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.7；298 K；1.7M POTASSIUM PHOSPHATE
Resolution 2.39 Å R-free 0.198
6CRD INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) with tetrabrachion (TB) domain stalk Deposited 2018-03-16 Assembly 1 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Chain B 83–470（388 aa）
Chain E 83–470（388 aa）
Chain H 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；100 mM HEPES buffer at pH7.0 with 10% PEG6000
Resolution 2.57 Å R-free 0.306
6CRD INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) with tetrabrachion (TB) domain stalk Deposited 2018-03-16 Assembly 2 Insufficient information Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 83–470（388 aa）
Chain D 83–470（388 aa）
Chain F 83–470（388 aa）
Chain G 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；100 mM HEPES buffer at pH7.0 with 10% PEG6000
Resolution 2.57 Å R-free 0.306
6D3B INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) APO FORM Deposited 2018-04-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 82–470（389 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 CA CALCIUM ION × 8 GOL GLYCEROL × 16 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；1.4 M KH2PO4 + 3.0 M K2HPO4 (2:1)
Resolution 1.40 Å R-free 0.170
6HCX Influenza Virus N9 Neuraminidase A complex with Zanamivir molecule (Tern). Deposited 2018-08-16 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded CA CALCIUM ION × 8 GOL GLYCEROL × 12 ZMR ZANAMIVIR × 4 K POTASSIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.6；293 K；N9 crystals were grown by hanging-drop vapour diffusion against a reservoir of 1.9M potassium phosphate, pH 6.8, starting with equal volumes of N9 NA (10-15 mg/ml in water) and potassium phosphate buffer 1.4M KH2PO4:3M K2HPO4 in ratio 8:4, pH 6.6 at 20 degrees celsius. Inhibitor complexes obtained by soaking N9 crystals in a solution of 1.4M potassium phosphate buffer, pH 6.8, containing 5mM of inhibitor for 3 hours at 18 degrees celsius. Soaked in glycerol cryo-buffer.
Resolution 1.30 Å R-free 0.125
6HEB Influenza A Virus N9 Neuraminidase complex with Oseltamivir (Tern). Deposited 2018-08-20 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded CA CALCIUM ION × 8 GOL GLYCEROL × 24 G39 (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.6；293 K；N9 crystals were grown by hanging drop vapour diffusion against a reservoir of 1.9M potassium phosphate, pH 6.8, starting with equal volumes of N9 NA(10-15mg/ml in water) and potassium phosphate buffer 1.4M KH2PO4:3M K2HPO4 in ratio 8:4, pH 6.6 at 20 degrees celsius. Inhibitor complexeswere obtained by soaking N9 crystals in a solution of 1.4M potassium phosphate buffer, pH 6.8, containing 5 mM of inhibitor for 3 hours at 18 degrees celsius. Glycerol cryo-buffer also soaked in.
Resolution 1.75 Å R-free 0.142
6HFC Influenza A Virus N9 Neuraminidase Native (Tern). Deposited 2018-08-21 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded CA CALCIUM ION × 8 GOL GLYCEROL × 28 K POTASSIUM ION × 8 CO2 CARBON DIOXIDE × 4 PO4 PHOSPHATE ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.6；293 K；N9 crystals were grown by-hanging drop vapour diffusion against a reservoir of 1.9M potassium phosphate, pH 6.8, starting with equal volumes of N9 NA solution (10 to 15 mg/ml in water) and potassium phosphate buffer 1.4M KH2PO4: 3M K2HPO4 in ratio 8:4, pH 6.6 at 20 degrees celsius. Large rhombic dodecahedral crystals grew within a few days.
Resolution 1.29 Å R-free 0.164
6HG0 Influenza A Virus N9 Neuraminidase complex with NANA (Tern/Australia). Deposited 2018-08-22 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded CA CALCIUM ION × 8 GOL GLYCEROL × 16 PO4 PHOSPHATE ION × 4 SIA N-acetyl-alpha-neuraminic acid × 8 K POTASSIUM ION × 4 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6.6；293 K；N9 crystals were grown by hanging-drop vapour diffusion against a reservoir of 1.9M potassium phosphate, pH 6.8, starting with equal volumes of N9 NA (10-15 mg/ml in water) and potassium phosphate buffer 1.4M KH2PO4:3M K2HPO4 in ratio 8:4, pH 6.6 at 20 degrees celsius. Inhibitor complexes obtained by soaking N9 crystals in a solution of 1.4M potassium phosphate buffer, pH 6.8, containing 5mM of inhibitor for 3 hours at 4 degrees celsius. Soaked in glycerol cryo-buffer.
Resolution 1.30 Å R-free 0.120
6MCX INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) RECOMBINANT HEAD DOMAIN Deposited 2018-09-02 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 GOL GLYCEROL × 12 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；298 K；1.4 M KH2PO4 + 3.0 M K2HPO4 (2:1), PH 7.0, VAPOR DIFFUSION, HANGING DROP,
Resolution 2.30 Å R-free 0.206
6NN9 REFINED ATOMIC STRUCTURES OF N9 SUBTYPE INFLUENZA VIRUS NEURAMINIDASE AND ESCAPE MUTANTS Deposited 1991-03-28 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.30 Å
7NN9 NATIVE INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) Deposited 1995-03-15 Assembly 1 Other combination Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain A 83–470（388 aa）
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 CA CALCIUM ION × 4 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.00 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.