Current Protein Identity:P03495
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1AIL N-TERMINAL FRAGMENT OF NS1 PROTEIN FROM INFLUENZA A VIRUS Deposited 1997-04-21 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–72(72 aa)
Fragment:RNA-BINDING DOMAIN
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5;NATIVE CRYSTALS WERE GROWN FROM 50MM NAH2PO4, 100MM NACL, 1MM NAN3 AT PH 6.5; MERCURY DERIVATIVE CRYSTAL WAS PREPARED BY SOAKING THE NATIVE CRYSTAL IN 2MM CH3HGCL WITH 10% PEG 6000 AT PH 8.0; PLATINUM DERIVATIVE CRYSTAL WAS PREPARED BY SOAKING THE NATIVE CRYSTAL IN 4MM PT(NH3)2CL2 WITH 10% PEG 6000 AT PH 6.5.
|
Resolution 1.90 Å R-free 0.229 |
| 1NS1 RNA-BINDING DOMAIN OF NON-STRUCTURAL PROTEIN 1 FROM INFLUENZA VIRUS, NMR, 16 STRUCTURES Deposited 1997-10-02 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–73(73 aa)
Fragment:RNA-BINDING DOMAIN, RESIDUES 1 - 73
Chain B
1–73(73 aa)
Fragment:RNA-BINDING DOMAIN, RESIDUES 1 - 73
|
Not recorded | No recorded non-water small molecule | SOLUTION NMR |
NMR measurement conditions
pH 6;293 K
|
Resolution not provided |
| 2RHK Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A Deposited 2007-10-09 | Assembly 1 Protein heterocomplex Heteromer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
Chain B
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
|
Not recorded | NO3 NITRATE ION × 5 ZN ZINC ION × 4 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.5;293 K;0.5 M KNO3, 10% sucroes, 0.1M sodium acitate, pH 5.5, EVAPORATION, temperature 293K, pH 5.50
|
Resolution 1.95 Å R-free 0.234 |
| 2RHK Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A Deposited 2007-10-09 | Assembly 2 Protein heterocomplex Heteromer;Protein × 6 PDB declaration: hexameric(6) Consistent with protein count |
Chain A
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
Chain B
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
|
Not recorded | NO3 NITRATE ION × 9 ZN ZINC ION × 6 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.5;293 K;0.5 M KNO3, 10% sucroes, 0.1M sodium acitate, pH 5.5, EVAPORATION, temperature 293K, pH 5.50
|
Resolution 1.95 Å R-free 0.234 |
| 2RHK Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A Deposited 2007-10-09 | Assembly 3 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
|
Not recorded | NO3 NITRATE ION × 5 ZN ZINC ION × 4 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.5;293 K;0.5 M KNO3, 10% sucroes, 0.1M sodium acitate, pH 5.5, EVAPORATION, temperature 293K, pH 5.50
|
Resolution 1.95 Å R-free 0.234 |
| 2RHK Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A Deposited 2007-10-09 | Assembly 4 Protein heterocomplex Heteromer;Protein × 3 PDB declaration: trimeric(3) Consistent with protein count |
Chain A
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
Chain B
85–215(131 aa)
Fragment:NS1A effector domain (UNP residues 85-215)
|
Not recorded | NO3 NITRATE ION × 4 ZN ZINC ION × 2 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.5;293 K;0.5 M KNO3, 10% sucroes, 0.1M sodium acitate, pH 5.5, EVAPORATION, temperature 293K, pH 5.50
|
Resolution 1.95 Å R-free 0.234 |
| 3EE8 Structure of NS1 effector domain Deposited 2008-09-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
84–205(122 aa)
Fragment:Effector domain (UNP residues 84-205)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6;298 K;12% (w/v) PEG3350, and 4% (v/v) Tacsimate (pH6.0), VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 2.60 Å R-free 0.284 |
| 3EE8 Structure of NS1 effector domain Deposited 2008-09-04 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
84–205(122 aa)
Fragment:Effector domain (UNP residues 84-205)
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP;pH 6;298 K;12% (w/v) PEG3350, and 4% (v/v) Tacsimate (pH6.0), VAPOR DIFFUSION, SITTING DROP, temperature 298K
|
Resolution 2.60 Å R-free 0.284 |
| 3EE9 Structure of NS1 effector domain Deposited 2008-09-04 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
84–205(122 aa)
Fragment:Effector domain (UNP residues 84-205)
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch;pH 5.5;298 K;20% (w/v) PEG400, 0.1M CH3COONa (pH5.5), 0.1M MgSO4, Batch, temperature 298K
|
Resolution 2.14 Å R-free 0.234 |
| 3EE9 Structure of NS1 effector domain Deposited 2008-09-04 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
84–205(122 aa)
Fragment:Effector domain (UNP residues 84-205)
|
Not recorded | SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
Batch;pH 5.5;298 K;20% (w/v) PEG400, 0.1M CH3COONa (pH5.5), 0.1M MgSO4, Batch, temperature 298K
|
Resolution 2.14 Å R-free 0.234 |
| 3KWG X-ray structure of NS1 effector domain W187A mutant Deposited 2009-12-01 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
78–205(128 aa)
Fragment:NS1 effector domain
|
Mutation:W187A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;277 K;0.3M magnesium formate, 0.1M Bis-Tris , pH 5.5, EVAPORATION, temperature 277K
|
Resolution 2.21 Å R-free 0.233 |
| 3KWG X-ray structure of NS1 effector domain W187A mutant Deposited 2009-12-01 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
78–205(128 aa)
Fragment:NS1 effector domain
|
Mutation:W187A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;277 K;0.3M magnesium formate, 0.1M Bis-Tris , pH 5.5, EVAPORATION, temperature 277K
|
Resolution 2.21 Å R-free 0.233 |
| 3KWG X-ray structure of NS1 effector domain W187A mutant Deposited 2009-12-01 | Assembly 3 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
78–205(128 aa)
Fragment:NS1 effector domain
Chain B
78–205(128 aa)
Fragment:NS1 effector domain
|
Mutation:W187A Mutation:W187A | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;277 K;0.3M magnesium formate, 0.1M Bis-Tris , pH 5.5, EVAPORATION, temperature 277K
|
Resolution 2.21 Å R-free 0.233 |
| 3KWI X-ray structure of NS1 effector domain W187Y mutant Deposited 2009-12-01 | Assembly 1 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain A
78–205(128 aa)
Fragment:NS1 effector domain
|
Mutation:W187Y | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;277 K;0.3M magnesium formate and 0.1M Bis-Tris , pH 5.5, EVAPORATION, temperature 277K
|
Resolution 2.21 Å R-free 0.258 |
| 3KWI X-ray structure of NS1 effector domain W187Y mutant Deposited 2009-12-01 | Assembly 2 Protein monomer Monomer;Protein × 1 PDB declaration: monomeric(1) Consistent with protein count |
Chain B
78–205(128 aa)
Fragment:NS1 effector domain
|
Mutation:W187Y | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION;pH 5.5;277 K;0.3M magnesium formate and 0.1M Bis-Tris , pH 5.5, EVAPORATION, temperature 277K
|
Resolution 2.21 Å R-free 0.258 |