Current Protein Identity：P05362
New Search
Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1D3E CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 16 (HRV16) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 1 Insufficient information Heteromer；Protein × 300 PDB declaration: 300-MERIC（300） Consistent with protein count |
Chain 1
28–212（185 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV16 WAS INCUBATED WITH D1D2-ICAM-1 FOR 16 HOURS AT 34
DEGREES CELSIUS (307 KELVIN) USING A SIXTEEN-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER
|
Resolution 28.00 Å |
| 1D3E CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 16 (HRV16) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 2 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain 1
28–212（185 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV16 WAS INCUBATED WITH D1D2-ICAM-1 FOR 16 HOURS AT 34
DEGREES CELSIUS (307 KELVIN) USING A SIXTEEN-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER
|
Resolution 28.00 Å |
| 1D3E CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 16 (HRV16) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 3 Insufficient information Heteromer；Protein × 25 PDB declaration: 25-meric（25） Consistent with protein count |
Chain 1
28–212（185 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV16 WAS INCUBATED WITH D1D2-ICAM-1 FOR 16 HOURS AT 34
DEGREES CELSIUS (307 KELVIN) USING A SIXTEEN-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER
|
Resolution 28.00 Å |
| 1D3E CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 16 (HRV16) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 4 Insufficient information Heteromer；Protein × 30 PDB declaration: 30-meric（30） Consistent with protein count |
Chain 1
28–212（185 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV16 WAS INCUBATED WITH D1D2-ICAM-1 FOR 16 HOURS AT 34
DEGREES CELSIUS (307 KELVIN) USING A SIXTEEN-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER
|
Resolution 28.00 Å |
| 1D3E CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 16 (HRV16) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 5 Insufficient information Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain 1
28–212（185 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV16 WAS INCUBATED WITH D1D2-ICAM-1 FOR 16 HOURS AT 34
DEGREES CELSIUS (307 KELVIN) USING A SIXTEEN-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER
|
Resolution 28.00 Å |
| 1D3I CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 14 (HRV14) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 1 Protein heterocomplex Heteromer；Protein × 300 PDB declaration: 300-MERIC（300） Consistent with protein count |
Chain I
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV14 WAS INCUBATED WITH D1D2-ICAM-1 FOR 30 MINUTES AT 4
DEGREES CELSIUS (277 KELVIN) USING AN EIGHT-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER.
|
Resolution 26.00 Å |
| 1D3I CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 14 (HRV14) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 2 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain I
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV14 WAS INCUBATED WITH D1D2-ICAM-1 FOR 30 MINUTES AT 4
DEGREES CELSIUS (277 KELVIN) USING AN EIGHT-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER.
|
Resolution 26.00 Å |
| 1D3I CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 14 (HRV14) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 3 Protein heterocomplex Heteromer；Protein × 25 PDB declaration: 25-meric（25） Consistent with protein count |
Chain I
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV14 WAS INCUBATED WITH D1D2-ICAM-1 FOR 30 MINUTES AT 4
DEGREES CELSIUS (277 KELVIN) USING AN EIGHT-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER.
|
Resolution 26.00 Å |
| 1D3I CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 14 (HRV14) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 4 Protein heterocomplex Heteromer；Protein × 30 PDB declaration: 30-meric（30） Consistent with protein count |
Chain I
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV14 WAS INCUBATED WITH D1D2-ICAM-1 FOR 30 MINUTES AT 4
DEGREES CELSIUS (277 KELVIN) USING AN EIGHT-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER.
|
Resolution 26.00 Å |
| 1D3I CRYO-EM STRUCTURE OF HUMAN RHINOVIRUS 14 (HRV14) COMPLEXED WITH A TWO-DOMAIN FRAGMENT OF ITS CELLULAR RECEPTOR, INTERCELLULAR ADHESION MOLECULE-1 (D1D2-ICAM-1). IMPLICATIONS FOR VIRUS-RECEPTOR INTERACTIONS. ALPHA CARBONS ONLY Deposited 1999-09-29 | Assembly 5 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count |
Chain I
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5
cryo-EM vitrification conditions
HRV14 WAS INCUBATED WITH D1D2-ICAM-1 FOR 30 MINUTES AT 4
DEGREES CELSIUS (277 KELVIN) USING AN EIGHT-FOLD EXCESS
OF D1D2-ICAM-1 FOR EACH OF THE SIXTY POSSIBLE BINDING
SITES PER VIRION. AFTER INCUBATION, SAMPLES WERE PREPARED
AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT NEAR
LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
WITH A GATAN 626 CRYOTRANSFER HOLDER.
|
Resolution 26.00 Å |
| 1D3L D1D2-ICAM-1 FULLY GLYCOSYLATED, VARIATION OF D1-D2 INTERDOMAIN ANGLE IN DIFFERENT CRYSTAL STRUCTURES. Deposited 1999-09-29 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
28–212（185 aa）
Fragment：FIRST TWO DOMAINS, RESIDUES 1-185
|
Not recorded | No recorded non-water small molecule | X-RAY DIFFRACTION |
X-ray crystallization conditions
PROTEIN WAS DESIALATED WITH NEURAMINIDASE (8 HR AT 37 DEGREES IN 100 MM SODIUM
ACETATE, PH 6.5, 10 MG/ML PROTEIN, 0.1 ENZYME UNIT/ML), DIALYZED AGAINST 10 MM TRIS, 25 MM NACL (PH 6.0), AND
PASSED THROUGH MONO-Q COLUMN. DESIALATED MATERIAL WAS
CRYSTALLIZED BY HANGING DROP METHODS: 17 MG/ML PROTEIN
IN BUFFER: 10 MM TRIS,25 MM NACL,1 MM MGCL2,1 MM CACL2,
WAS PRECIPITATED FROM 24-27% PEG 3350 IN SAME BUFFER.
|
Resolution 3.25 Å |
| 1IAM STRUCTURE OF THE TWO AMINO-TERMINAL DOMAINS OF HUMAN INTERCELLULAR ADHESION MOLECULE-1, ICAM-1 Deposited 1998-02-22 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
28–212（185 aa）
Fragment：TWO N-TERMINAL, IMMUNOGLOBULIN DOMAINS
|
Mutation：N103Q, N118Q, N156Q | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.5；PROTEIN IN 10 MM TRIS, PH 7.5, 25 MM NACL, WAS CRYSTALLIZED FROM 20% PEG 4000 IN 10 MM TRIS AS PRECIPITANT
|
Resolution 2.10 Å R-free 0.303 |
| 1IC1 THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1 Deposited 1998-03-09 | Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
28–217（190 aa）
Fragment：N-TERMINAL 190 RESIDUE DOMAIN
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；17% PEG 4000, NA CACODYLATE, PH 6.5, AND 100 MM B-OCTYL-GLUCOPYRANOSIDE.
|
Resolution 3.00 Å R-free 0.279 |
| 1IC1 THE CRYSTAL STRUCTURE FOR THE N-TERMINAL TWO DOMAINS OF ICAM-1 Deposited 1998-03-09 | Assembly 2 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
28–217（190 aa）
Fragment：N-TERMINAL 190 RESIDUE DOMAIN
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 6.5；17% PEG 4000, NA CACODYLATE, PH 6.5, AND 100 MM B-OCTYL-GLUCOPYRANOSIDE.
|
Resolution 3.00 Å R-free 0.279 |
| 1MQ8 Crystal structure of alphaL I domain in complex with ICAM-1 Deposited 2002-09-15 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
28–318（291 aa）
Fragment：domains 1 and 2
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；25% PEG 4000, 0.1 M sodium acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP at 298K
|
Resolution 3.30 Å R-free 0.313 |
| 1MQ8 Crystal structure of alphaL I domain in complex with ICAM-1 Deposited 2002-09-15 | Assembly 2 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
28–318（291 aa）
Fragment：domains 1 and 2
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；25% PEG 4000, 0.1 M sodium acetate, pH 4.6, VAPOR DIFFUSION, HANGING DROP at 298K
|
Resolution 3.30 Å R-free 0.313 |
| 1P53 The Crystal Structure of ICAM-1 D3-D5 fragment Deposited 2003-04-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
212–477（266 aa）
Fragment：ICAM-1 extracellular Domain 3-5, ecto-fragment
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；15mg/ml protein, NH4H2PO4, 0.1 M Na-citrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.06 Å R-free 0.252 |
| 1P53 The Crystal Structure of ICAM-1 D3-D5 fragment Deposited 2003-04-24 | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain B
212–477（266 aa）
Fragment：ICAM-1 extracellular Domain 3-5, ecto-fragment
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；15mg/ml protein, NH4H2PO4, 0.1 M Na-citrate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 3.06 Å R-free 0.252 |
| 1Z7Z Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi Deposited 2005-03-28 | Assembly 1 Protein heterocomplex Heteromer；Protein × 360 PDB declaration: 360-MERIC（360） Consistent with protein count |
Chain I
28–477（450 aa）
Fragment：ICAM-1 EXTRACELLULAR DOMAIN 1-5
|
Mutation：K29M | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 480 | ELECTRON MICROSCOPY |
cryo-EM buffer
TRIS；pH 7.2；TRIS
cryo-EM vitrification conditions
Cryogen ETHANE；PLUNGED INTO ETHANE AT LIQUID NITROGEN TEMPERATURE
|
Resolution 8.00 Å |
| 1Z7Z Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi Deposited 2005-03-28 | Assembly 2 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain I
28–477（450 aa）
Fragment：ICAM-1 EXTRACELLULAR DOMAIN 1-5
|
Mutation：K29M | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 | ELECTRON MICROSCOPY |
cryo-EM buffer
TRIS；pH 7.2；TRIS
cryo-EM vitrification conditions
Cryogen ETHANE；PLUNGED INTO ETHANE AT LIQUID NITROGEN TEMPERATURE
|
Resolution 8.00 Å |
| 1Z7Z Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi Deposited 2005-03-28 | Assembly 3 Protein heterocomplex Heteromer；Protein × 30 PDB declaration: 30-meric（30） Consistent with protein count |
Chain I
28–477（450 aa）
Fragment：ICAM-1 EXTRACELLULAR DOMAIN 1-5
|
Mutation：K29M | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 40 | ELECTRON MICROSCOPY |
cryo-EM buffer
TRIS；pH 7.2；TRIS
cryo-EM vitrification conditions
Cryogen ETHANE；PLUNGED INTO ETHANE AT LIQUID NITROGEN TEMPERATURE
|
Resolution 8.00 Å |
| 1Z7Z Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi Deposited 2005-03-28 | Assembly 4 Protein heterocomplex Heteromer；Protein × 36 PDB declaration: 36-meric（36） Consistent with protein count |
Chain I
28–477（450 aa）
Fragment：ICAM-1 EXTRACELLULAR DOMAIN 1-5
|
Mutation：K29M | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 48 | ELECTRON MICROSCOPY |
cryo-EM buffer
TRIS；pH 7.2；TRIS
cryo-EM vitrification conditions
Cryogen ETHANE；PLUNGED INTO ETHANE AT LIQUID NITROGEN TEMPERATURE
|
Resolution 8.00 Å |
| 1Z7Z Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi Deposited 2005-03-28 | Assembly 5 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count |
Chain I
28–477（450 aa）
Fragment：ICAM-1 EXTRACELLULAR DOMAIN 1-5
|
Mutation：K29M | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 | ELECTRON MICROSCOPY |
cryo-EM buffer
TRIS；pH 7.2；TRIS
cryo-EM vitrification conditions
Cryogen ETHANE；PLUNGED INTO ETHANE AT LIQUID NITROGEN TEMPERATURE
|
Resolution 8.00 Å |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 10 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain S
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 11 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain U
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 12 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain W
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 13 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain Y
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 14 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain a
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain C
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 3 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain E
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 4 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain G
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 5 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain I
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 6 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain K
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 7 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain M
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 8 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain O
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 3TCX Structure of Engineered Single Domain ICAM-1 D1 with High-Affinity aL Integrin I Domain of Native C-Terminal Helix Conformation Deposited 2011-08-09 | Assembly 9 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain Q
29–112（84 aa）
Fragment：DOMAIN 1, unp residues 29-112
|
Mutation：T2V, I10T, T23A, P38V, P63V, S67A, T78A | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 6；277 K；pH 6.0, EVAPORATION, temperature 277K
|
Resolution 3.60 Å R-free 0.234 |
| 5MZA The DBLb domain of PF11_0521 PfEMP1 bound to human ICAM-1 Deposited 2017-01-31 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
28–212（185 aa）
|
Not recorded | 3PO TRIPHOSPHATE × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 IHP INOSITOL HEXAKISPHOSPHATE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；277 K；10% (w/v) PEG 20000, 20% (v/v) PEG 500 and 0.1M Tris-BICINE (pH 8.5)
|
Resolution 2.78 Å R-free 0.236 |
| 6EIT Coxsackievirus A24v in complex with the D1-D2 fragment of ICAM-1 Deposited 2017-09-19 | Assembly 1 Protein heterocomplex Heteromer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count |
Chain 4
28–112（85 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.5；TBS buffer (Coxsackievirus A24v)
Phosphate buffer (ICAM-1 D1-D2)
cryo-EM vitrification conditions
Cryogen ETHANE；On-grid binding of the receptor was performed by applying 3 microliters of ICAM-1 (9.85 mg/ml) to the pre-blotted, virus-containing grid, and leaving for 30 seconds before blotting and freezing
|
Resolution 3.90 Å |
| 6S8U Structure of the PfEMP1 IT4var13 DBLbeta domain bound to ICAM-1 Deposited 2019-07-10 | Assembly 1 Other combination Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain B
28–212（185 aa）
|
Not recorded | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；291 K；0.1M Tris pH 8, 25% PEG 350 MME
|
Resolution 3.67 Å R-free 0.286 |
| 7BG7 HRV14 in complex with its receptor ICAM-1 Deposited 2021-01-06 | Assembly 1 Protein heterocomplex Heteromer；Protein × 300 PDB declaration: 300-meric（300） Consistent with protein count |
Chain B
28–480（453 aa）
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 7.4；PBS
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 2.40 Å |