当前蛋白身份：P06602
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 1JGG Even-skipped Homeodomain Complexed to AT-rich DNA 提交 2001-06-25 | Assembly 1 蛋白–DNA 同源多聚体；蛋白 × 2 PDB 声明：tetrameric（4） 与全部聚合物一致 |
链 A
70–129（60 aa）
片段：Homeodomain
链 B
70–129（60 aa）
片段：Homeodomain
|
未记录 | 未记录非水小分子 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.4；293 K；sodium acetate, potassium chloride, DTT, pH 6.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.00 Å R-free 0.316 |
| 9YZL Isoreticular co-crystal of Replication Initiator Protein REPE54 and asymmetrical expanded duplex (31mer) containing the cognate REPE54 sequence, and additional T-A rich sequence with 5' terminal phosphates. Two copies of Even-skipped homeodomain loaded post-crystallization 提交 2025-10-30 | Assembly 1 蛋白–DNA 异源复合物；蛋白 × 3 PDB 声明：pentameric（5） 与全部聚合物一致 |
链 D
69–129（61 aa）
链 E
69–129（61 aa）
|
未记录 | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；30mM Magnesium Acetate, 1.2M Lithium sulfate, 50mM MES pH 6.5. The crystal was crosslinked with 33mg/mL EDC overnight, and then looped into a solution of 15mM potassium chloride, 4mM calcium chloride, 10% glycerol, and 10mM Tris hydrochloride for 1 hour. The drop was then supplemented with 30 micromolar Even-skipped homeodomain
|
分辨率 3.02 Å R-free 0.294 |
| 9YZM Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence CTAATTAGGC and loaded with Even-skipped homeodomain 提交 2025-10-30 | Assembly 1 蛋白–DNA 异源复合物；蛋白 × 3 PDB 声明：pentameric（5） 与全部聚合物一致 |
链 D
69–129（61 aa）
链 E
69–129（61 aa）
|
未记录 | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；30mM magnesium acetate, 1.1M lithium sulfate, 50mM MES pH 6.5. The crystal was crosslinked with 33mg/mL EDC overnight, and then looped into a solution of 50mM potassium chloride, 4mM calcium chloride, 10% glycerol, and 10mM Tris hydrochloride for 1 hour. The drop was then supplemented with 30 micromolar Even-skipped homeodomain.
|
分辨率 3.07 Å R-free 0.269 |
| 9YZN Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence TGATGAGCAG and loaded with Even-skipped homeodomain 提交 2025-10-30 | Assembly 1 蛋白–DNA 异源复合物；蛋白 × 3 PDB 声明：pentameric（5） 与全部聚合物一致 |
链 D
69–129（61 aa）
链 E
69–129（61 aa）
|
未记录 | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；40mM Magnesium acetate, 1.4M Lithium sulfate, 50mM MES pH 6.5. The crystal was crosslinked with 33mg/mL EDC overnight, and then looped into a solution of 25mM potassium chloride, 4mM calcium chloride, 10% glycerol, and 10mM Tris hydrochloride for 1 hour. The drop was then supplemented with 30 micromolar Even-skipped homeodomain.
|
分辨率 3.16 Å R-free 0.283 |
| 9YZO Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence TGATGAGCAG and loaded with Even-skipped homeodomain 提交 2025-10-30 | Assembly 1 蛋白–DNA 异源复合物；蛋白 × 3 PDB 声明：pentameric（5） 与全部聚合物一致 |
链 D
69–129（61 aa）
链 E
69–129（61 aa）
|
未记录 | MG MAGNESIUM ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；20mM magnesium acetate, 1.7M lithium sulfate, 50mM MES pH 6.5. The crystal was crosslinked with 33mg/mL EDC overnight, and then looped into a solution of 50mM potassium chloride, 4mM calcium chloride, 10% glycerol, and 10mM Tris hydrochloride for 1 hour. The drop was then supplemented with 30 micromolar Even-skipped homeodomain.
|
分辨率 2.96 Å R-free 0.312 |
| 9YZS Isoreticular co-crystal 1 with asymmetrical expanded duplex (31mer) containing insert sequence TAATTAGGCCG and loaded with Even-skipped homeodomain 提交 2025-10-30 | Assembly 1 蛋白–DNA 异源复合物；蛋白 × 3 PDB 声明：pentameric（5） 与全部聚合物一致 |
链 D
69–129（61 aa）
片段：Even-skipped homeodomain
链 E
69–129（61 aa）
片段：Even-skipped homeodomain
|
未记录 | MG MAGNESIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 6.5；298 K；30mM magnesium acetate, 800mM lithium sulfate, 50mM MES pH 6.5. The crystal was crosslinked with 47.5mg/mL EDC overnight, and then looped into a solution of 50mM potassium chloride, 4mM calcium chloride, 10% glycerol, and 10mM Tris hydrochloride for 1 hour. The drop was then supplemented with 30 micromolar Even-skipped homeodomain.
|
分辨率 3.08 Å R-free 0.291 |