Current Protein Identity:P08773
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1B49 DCMP HYDROXYMETHYLASE FROM T4 (PHOSPHATE-BOUND) Deposited 1999-01-06 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
Chain C
1–246(246 aa)
|
Not recorded | PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 2.30 Å R-free 0.202 |
| 1B5D DCMP Hydroxymethylase from T4 (Intact) Deposited 1999-01-06 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–246(246 aa)
Chain B
1–246(246 aa)
|
Not recorded | DCM 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 2.20 Å R-free 0.208 |
| 1B5D DCMP Hydroxymethylase from T4 (Intact) Deposited 1999-01-06 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
Chain B
1–246(246 aa)
|
Not recorded | DCM 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 2.20 Å R-free 0.208 |
| 1B5E DCMP HYDROXYMETHYLASE FROM T4 Deposited 1999-01-06 | Assembly 1 Protein homooligomer Homooligomer;Protein × 4 PDB declaration: tetrameric(4) Consistent with protein count |
Chain A
1–246(246 aa)
Chain B
1–246(246 aa)
|
Not recorded | DCM 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 1.60 Å R-free 0.208 |
| 1B5E DCMP HYDROXYMETHYLASE FROM T4 Deposited 1999-01-06 | Assembly 2 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
Chain B
1–246(246 aa)
|
Not recorded | DCM 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 8;pH 8.0
|
Resolution 1.60 Å R-free 0.208 |
| 6A9A Ternary complex crystal structure of dCH with dCMP and THF Deposited 2018-07-12 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
|
Mutation:C148S, D179N | IOD IODIDE ION × 2 DCM 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE × 2 THG (6S)-5,6,7,8-TETRAHYDROFOLATE × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;298 K;Tris-HCl pH 8.0, Sodium citrate
|
Resolution 1.90 Å R-free 0.187 |
| 6A9B T4 dCMP hydroxymethylase structure solved by I-SAD using a home source Deposited 2018-07-12 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
|
Not recorded | IOD IODIDE ION × 2 PO4 PHOSPHATE ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP;pH 8.5;298 K;0.1 M Tris-HCl pH 8.5 0.96 M sodium citrate
|
Resolution 2.01 Å R-free 0.192 |
| 6L18 XFEL structure of T4dCH D179N mutant complex with natively expressed dTMP Deposited 2019-09-27 | Assembly 1 Protein homooligomer Homooligomer;Protein × 2 PDB declaration: dimeric(2) Consistent with protein count |
Chain A
1–246(246 aa)
|
Mutation:D179N | TMP THYMIDINE-5'-PHOSPHATE × 2 IOD IODIDE ION × 2 NA SODIUM ION × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
SMALL TUBES;pH 8.5;293 K;2 ul of 1.0 M Tris-HCl pH 8.5
2 ul of 1.0 M NaI
17 ul of C6H5Na3 2H2O
10 ul of 40mg/ml D179N mutant protein
|
Resolution 1.90 Å R-free 0.191 |