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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P12823 New Search
10PDB entries
24Biological assembly
72chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1L9K dengue methyltransferase Deposited 2002-03-25 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2492–2784（293 aa） Fragment：NS5 N-terminal domain
Mutation：V135I, K139R, N173S, P188S, R193K, T196A, Y201H SO4 SULFATE ION × 5 SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；291 K；sodium citrate 100mM, lithium sulfate 1.2 M, ammonium sulfate 0.5 M, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.40 Å R-free 0.257
1L9K dengue methyltransferase Deposited 2002-03-25 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2492–2784（293 aa） Fragment：NS5 N-terminal domain
Mutation：V135I, K139R, N173S, P188S, R193K, T196A, Y201H SO4 SULFATE ION × 10 SAH S-ADENOSYL-L-HOMOCYSTEINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；291 K；sodium citrate 100mM, lithium sulfate 1.2 M, ammonium sulfate 0.5 M, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.40 Å R-free 0.257
1OAN Crystal structure of the dengue 2 virus envelope protein Deposited 2003-01-16 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 281–674（394 aa） Fragment：SOLUBLE ECTODOMAIN, RESIDUES 281-674
Chain B 281–674（394 aa） Fragment：SOLUBLE ECTODOMAIN, RESIDUES 281-674
Not recorded NA SODIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；11% PEG 8000, 1 M NACL, 0.1 M TRIS/HCL PH 9.0, 20% GLYCEROL
Resolution 2.75 Å R-free 0.296
1OK8 Crystal structure of the dengue 2 virus envelope glycoprotein in the postfusion conformation Deposited 2003-07-19 Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 281–674（394 aa） Fragment：SOLUBLE ECTODOMAIN, RESIDUES 281-674
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 CL CHLORIDE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions pH 7；20-30% PEG 400, 0.08 M NACL, 0.1 M MOPS PH 7-8.
Resolution 2.00 Å R-free 0.267
1OKE Crystal structure of the dengue 2 virus envelope protein in complex with n-octyl-beta-D-glucoside Deposited 2003-07-22 Assembly 1 Other combination Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 281–674（394 aa） Fragment：SOLUBLE ECTODOMAIN, RESIDUES 281-674
Chain B 281–674（394 aa） Fragment：SOLUBLE ECTODOMAIN, RESIDUES 281-674
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 BOG octyl beta-D-glucopyranoside × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8.5；11% PEG 8K, 1M NACL, 0.1M TRIS/HCL PH 9.0, 20% GLYCEROL,0.5% OCTYLGLUCOSIDE
Resolution 2.40 Å R-free 0.294
1P58 Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction Deposited 2003-04-25 Assembly 1 Protein homooligomer Homooligomer；Protein × 360 PDB declaration: 360-MERIC（360） Consistent with protein count
Chain A 281–775（495 aa）
Chain B 281–775（495 aa）
Chain C 281–775（495 aa）
Chain D 206–280（75 aa）
Chain E 206–280（75 aa）
Chain F 206–280（75 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NaCl, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1P58 Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction Deposited 2003-04-25 Assembly 2 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 281–775（495 aa）
Chain B 281–775（495 aa）
Chain C 281–775（495 aa）
Chain D 206–280（75 aa）
Chain E 206–280（75 aa）
Chain F 206–280（75 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NaCl, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1P58 Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction Deposited 2003-04-25 Assembly 3 Protein homooligomer Homooligomer；Protein × 30 PDB declaration: 30-meric（30） Consistent with protein count
Chain A 281–775（495 aa）
Chain B 281–775（495 aa）
Chain C 281–775（495 aa）
Chain D 206–280（75 aa）
Chain E 206–280（75 aa）
Chain F 206–280（75 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NaCl, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1P58 Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction Deposited 2003-04-25 Assembly 4 Protein homooligomer Homooligomer；Protein × 36 PDB declaration: 36-meric（36） Consistent with protein count
Chain A 281–775（495 aa）
Chain B 281–775（495 aa）
Chain C 281–775（495 aa）
Chain D 206–280（75 aa）
Chain E 206–280（75 aa）
Chain F 206–280（75 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NaCl, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1P58 Complex Organization of Dengue Virus Membrane Proteins as Revealed by 9.5 Angstrom Cryo-EM reconstruction Deposited 2003-04-25 Assembly 5 Protein homooligomer Homooligomer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain A 281–775（495 aa）
Chain B 281–775（495 aa）
Chain C 281–775（495 aa）
Chain D 206–280（75 aa）
Chain E 206–280（75 aa）
Chain F 206–280（75 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NaCl, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NaCl, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1R6A Structure of the dengue virus 2'O methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate Deposited 2003-10-15 Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 2492–2784（293 aa） Fragment：RNA-directed RNA polymerase (residue 2492-2784)
Not recorded SO4 SULFATE ION × 7 SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 RVP RIBAVIRIN MONOPHOSPHATE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；293 K；Na Citrate 0.1 M, AS 0.5 M, LiSO4 1.2 M, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.60 Å R-free 0.243
1R6A Structure of the dengue virus 2'O methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate Deposited 2003-10-15 Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 2492–2784（293 aa） Fragment：RNA-directed RNA polymerase (residue 2492-2784)
Not recorded SO4 SULFATE ION × 14 SAH S-ADENOSYL-L-HOMOCYSTEINE × 2 RVP RIBAVIRIN MONOPHOSPHATE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.8；293 K；Na Citrate 0.1 M, AS 0.5 M, LiSO4 1.2 M, pH 5.8, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.60 Å R-free 0.243
1R6R Solution Structure of Dengue Virus Capsid Protein Reveals a New Fold Deposited 2003-10-16 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–100（100 aa） Fragment：capsid protein C (residue 1-100)
Chain B 1–100（100 aa） Fragment：capsid protein C (residue 1-100)
Not recorded No recorded non-water small molecule SOLUTION NMR
NMR measurement conditions pH 6；300 K；Ionic strength (raw mmCIF value) 50 mM sodium phosphate and 200 mM NaCl；Pressure 1
NMR measurement conditions pH 6；305 K；Ionic strength (raw mmCIF value) 50 mM sodium phosphate and 200 mM NaCl；Pressure 1
NMR sample composition 0.8 mM DEN2C protein U-15N, 13C; in 90% H2O/10% D2O with 50 mM sodium phosphate and 200 mM NaCl at pH 6.0. in SHIGEMI tube | 90% H2O/10% D2O
NMR sample composition 1mM or 2 mM DEN2C protein U-15N; in 90% H2O/10% D2O with 50 mM sodium phosphate and 200 mM NaCl at pH 6.0. in SHIGEMI tube | 90% H2O/10% D2O
Resolution not provided
1THD COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION Deposited 2004-06-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 180 PDB declaration: 180-MERIC（180） Consistent with protein count
Chain A 281–675（395 aa）
Chain B 281–675（395 aa）
Chain C 281–675（395 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NACL, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NACL, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1THD COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION Deposited 2004-06-01 Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 281–675（395 aa）
Chain B 281–675（395 aa）
Chain C 281–675（395 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NACL, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NACL, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1THD COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION Deposited 2004-06-01 Assembly 3 Protein homooligomer Homooligomer；Protein × 15 PDB declaration: pentadecameric（15） Consistent with protein count
Chain A 281–675（395 aa）
Chain B 281–675（395 aa）
Chain C 281–675（395 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NACL, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NACL, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1THD COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION Deposited 2004-06-01 Assembly 4 Protein homooligomer Homooligomer；Protein × 18 PDB declaration: octadecameric（18） Consistent with protein count
Chain A 281–675（395 aa）
Chain B 281–675（395 aa）
Chain C 281–675（395 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NACL, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NACL, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
1THD COMPLEX ORGANIZATION OF DENGUE VIRUS E PROTEIN AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION Deposited 2004-06-01 Assembly 5 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 281–675（395 aa）
Chain B 281–675（395 aa）
Chain C 281–675（395 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 50 mM TRIS, 75 mM NACL, 1 mM EDTA；pH 7.6；50 mM TRIS, 75 mM NACL, 1 mM EDTA
cryo-EM vitrification conditions SAMPLES WERE PREPARED AS THIN LAYERS OF VITREOUS ICE AND MAINTAINED AT LIQUID NITROGEN TEMPERATURE IN THE ELECTRON MICROSCOPE
Resolution 9.50 Å
3J8D Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 Deposited 2014-10-13 Assembly 1 Protein heterocomplex Heteromer；Protein × 420 PDB declaration: 420-MERIC（420） Consistent with protein count
Chain G 281–674（394 aa） Fragment：UNP residues 281-674
Chain H 281–674（394 aa） Fragment：UNP residues 281-674
Chain I 281–674（394 aa） Fragment：UNP residues 281-674
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA；pH 5.5；120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liquid ethane
Resolution 26.00 Å
3J8D Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 Deposited 2014-10-13 Assembly 2 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain G 281–674（394 aa） Fragment：UNP residues 281-674
Chain H 281–674（394 aa） Fragment：UNP residues 281-674
Chain I 281–674（394 aa） Fragment：UNP residues 281-674
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA；pH 5.5；120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liquid ethane
Resolution 26.00 Å
3J8D Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 Deposited 2014-10-13 Assembly 3 Protein heterocomplex Heteromer；Protein × 35 PDB declaration: 35-meric（35） Consistent with protein count
Chain G 281–674（394 aa） Fragment：UNP residues 281-674
Chain H 281–674（394 aa） Fragment：UNP residues 281-674
Chain I 281–674（394 aa） Fragment：UNP residues 281-674
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA；pH 5.5；120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liquid ethane
Resolution 26.00 Å
3J8D Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 Deposited 2014-10-13 Assembly 4 Protein heterocomplex Heteromer；Protein × 42 PDB declaration: 42-meric（42） Consistent with protein count
Chain G 281–674（394 aa） Fragment：UNP residues 281-674
Chain H 281–674（394 aa） Fragment：UNP residues 281-674
Chain I 281–674（394 aa） Fragment：UNP residues 281-674
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA；pH 5.5；120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liquid ethane
Resolution 26.00 Å
3J8D Cryoelectron microscopy of dengue-Fab E104 complex at pH 5.5 Deposited 2014-10-13 Assembly 5 Protein heterocomplex Heteromer；Protein × 7 PDB declaration: heptameric（7） Consistent with protein count
Chain G 281–674（394 aa） Fragment：UNP residues 281-674
Chain H 281–674（394 aa） Fragment：UNP residues 281-674
Chain I 281–674（394 aa） Fragment：UNP residues 281-674
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer 120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA；pH 5.5；120 mM NaCl, 20 mM Tris HCl, 1 mM EDTA
cryo-EM vitrification conditions Cryogen ETHANE；Plunged into liquid ethane
Resolution 26.00 Å
5HHG Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex Deposited 2016-01-11 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain C 3353–3388（36 aa） Fragment：UNP residues 3353-3388
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7；296 K；1.5M Ammonium Sulfate, 0.1M Sodium HEPES
Resolution 2.20 Å R-free 0.214

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.