Current Protein Identity：P13009
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1BMT HOW A PROTEIN BINDS B12: A 3.O ANGSTROM X-RAY STRUCTURE OF THE B12-BINDING DOMAINS OF METHIONINE SYNTHASE Deposited 1994-09-02 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
650–895（246 aa）
Chain B
650–895（246 aa）
|
Not recorded | COB CO-METHYLCOBALAMIN × 2 | X-RAY DIFFRACTION | mmCIF provides none of the parsed conditions | Resolution 3.00 Å |
| 1K7Y E. coli MetH C-terminal fragment (649-1227) Deposited 2001-10-22 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
651–1227（577 aa）
Fragment：c-terminal activation complex, residues 651-1227
|
Mutation：H759G | SO4 SULFATE ION × 10 B12 COBALAMIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；295 K；cacodylate, ammonium sulfate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 3.00 Å R-free 0.276 |
| 1K98 AdoMet complex of MetH C-terminal fragment Deposited 2001-10-27 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
651–1227（577 aa）
Fragment：c-terminal activation complex, residues 651-1227
|
Mutation：H759G | SO4 SULFATE ION × 1 B12 COBALAMIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.5；295 K；cacodylate, ammonium sulfate, PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 295K
|
Resolution 3.75 Å R-free 0.363 |
| 1MSK METHIONINE SYNTHASE (ACTIVATION DOMAIN) Deposited 1996-08-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
896–1226（331 aa）
Fragment：ACTIVATION DOMAIN, RESIDUES 897 - 1227
|
Not recorded | ACT ACETATE ION × 1 SAM S-ADENOSYLMETHIONINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 7.2；pH 7.2
|
Resolution 1.80 Å R-free 0.257 |
| 3BUL E. coli I690C/G743C MetH C-terminal fragment (649-1227) Deposited 2008-01-03 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
649–1227（579 aa）
Fragment：C-terminal activation complex (residues 649-1227)
|
Mutation：I690C, G743C | B12 COBALAMIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
EVAPORATION；pH 7.2；310 K；0.2 M potassium nitrate, and 20 % (w/v) PEG3350, pH 7.2, EVAPORATION, temperature 310K
|
Resolution 2.30 Å R-free 0.247 |
| 3IV9 Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half in a "His-On" conformation Deposited 2009-08-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
649–1227（579 aa）
Fragment：C-terminal activation complex (UNP residues 649-1227)
|
Mutation：I690C, G743C | B12 COBALAMIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7.5；302 K；0.2 M potassium nitrate, 20 % (w/v) PEG3350, 50 mM HEPES pH 7.5, VAPOR DIFFUSION, temperature 302K
|
Resolution 3.25 Å R-free 0.321 |
| 3IVA Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half with AdoHcy bound Deposited 2009-08-31 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
649–1227（579 aa）
Fragment：C-terminal activation complex (UNP residues 649-1227)
|
Mutation：I690C, G743C | B12 COBALAMIN × 1 SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 NO3 NITRATE ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7；302 K；0.2 M potassium nitrate, 18 % (w/v) PEG3350, pH 7.0, VAPOR DIFFUSION, temperature 302K
|
Resolution 2.70 Å R-free 0.300 |
| 6BDY Crystal Structure of the MetH Reactivation Domain bound to Sinefungin Deposited 2017-10-24 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
897–1227（331 aa）
Fragment：reactivation domain
|
Not recorded | SFG SINEFUNGIN × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.3；293 K；28% PEG 6000, 100mM Tris pH 7.3, 300mM magnesium acetate:15mg/mL protein, 3mM sinefungin, 10mM Tris 7.2, 10mM EDTA, 2:2uL
|
Resolution 1.51 Å R-free 0.186 |
| 6BM5 Crystal Structure of the MetH Reactivation Domain bound to AdoMet Deposited 2017-11-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
897–1227（331 aa）
Fragment：reactivation domain
|
Not recorded | SAM S-ADENOSYLMETHIONINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.4；293 K；28% PEG 6000, 100mM Tris pH 7.4, 300mM magnesium acetate:15mg/mL protein, 3mM AdoMet, 10mM Tris 7.2, 10mM EDTA, 3:3uL
|
Resolution 1.50 Å R-free 0.194 |
| 6BM6 Crystal Structure of the MetH Reactivation Domain bound to AdoHcy Deposited 2017-11-13 | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count |
Chain A
897–1227（331 aa）
Fragment：reactivation domain
|
Not recorded | SAH S-ADENOSYL-L-HOMOCYSTEINE × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；27-32% PEG 6000, 100mM Tris pH 7.2-7.5, 300mM magnesium acetate:15mg/mL protein, 5mM AdoHcy, 20mM Tris 7.2, 20mM EDTA, 2:2uL
|
Resolution 1.50 Å R-free 0.204 |