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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P15529 New Search
7PDB entries
17Biological assembly
26chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 1 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain A 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 2 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain B 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 3 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain C 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 4 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain D 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 5 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain E 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
1CKL N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP) Deposited 1999-04-22 Assembly 6 Other combination Monomer；Protein × 1 PDB declaration: monomeric（1） Consistent with protein count
Chain F 35–160（126 aa） Fragment：N-TERMINAL TWO SCR DOMAINS
Not recorded CA CALCIUM ION × 1 CL CHLORIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；16% PEG 8000, 40 MM CACL2, 100 MM NA-CACODYLATE PH 6.5, 7 MG/ML PROTEIN, 20C, pH 6.50
Resolution 3.10 Å R-free 0.298
2O39 Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2006-12-01 Assembly 1 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain C 35–160（126 aa） Fragment：SCR1 and SCR 2 domains
Not recorded CA CALCIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；35% PEG 200, 200mM CaCl2, 100mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.85 Å R-free 0.273
2O39 Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2006-12-01 Assembly 2 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 35–160（126 aa） Fragment：SCR1 and SCR 2 domains
Not recorded CA CALCIUM ION × 6 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；35% PEG 200, 200mM CaCl2, 100mM Tris, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.85 Å R-free 0.273
3INB Structure of the measles virus hemagglutinin bound to the CD46 receptor Deposited 2009-08-12 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain C 35–160（126 aa） Fragment：Sushi domains 1 and 2, residues 35-160
Chain D 35–160（126 aa） Fragment：Sushi domains 1 and 2, residues 35-160
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 SO4 SULFATE ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6.5；293 K；12% PEG-8000, 0.2 M Ammonium Sulphate 2% PEG-400, 1% 1,2,3 heptanetriol, 1 mM Sodium Tungstate, 0.1 M Mes, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 3.10 Å R-free 0.259
3L89 Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2009-12-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain M 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain N 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain O 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；6% PEG 8000, 0.1M LiCl, pH 5.6, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.50 Å R-free 0.239
3L89 Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2009-12-30 Assembly 2 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain P 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain Q 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain R 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；6% PEG 8000, 0.1M LiCl, pH 5.6, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.50 Å R-free 0.239
3L89 Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2009-12-30 Assembly 3 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain S 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain T 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain U 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；6% PEG 8000, 0.1M LiCl, pH 5.6, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.50 Å R-free 0.239
3L89 Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) Deposited 2009-12-30 Assembly 4 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain V 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain W 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Chain X 35–160（126 aa） Fragment：CD46 SCR1 and SCR2 domains (UNP residues 35-160)
Not recorded NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.6；298 K；6% PEG 8000, 0.1M LiCl, pH 5.6, VAPOR DIFFUSION, SITTING DROP, temperature 298K
Resolution 3.50 Å R-free 0.239
3O8E Structure of extracelllar portion of CD46 in complex with Adenovirus type 11 knob Deposited 2010-08-03 Assembly 1 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain B 35–286（252 aa） Fragment：CD46 SCR1-SCR4 (UNP RESIDUES 35-286)
Not recorded DTD DITHIANE DIOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；298 K；microseeding, pH 8.0, VAPOR DIFFUSION, temperature 298K
Resolution 2.84 Å R-free 0.229
3O8E Structure of extracelllar portion of CD46 in complex with Adenovirus type 11 knob Deposited 2010-08-03 Assembly 2 Other combination Heteromer；Protein × 6 PDB declaration: hexameric（6） Consistent with protein count
Chain D 35–286（252 aa） Fragment：CD46 SCR1-SCR4 (UNP RESIDUES 35-286)
Not recorded DTD DITHIANE DIOL × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 8；298 K；microseeding, pH 8.0, VAPOR DIFFUSION, temperature 298K
Resolution 2.84 Å R-free 0.229
5FO8 Crystal Structure of Human Complement C3b in Complex with MCP (CCP1-4) Deposited 2015-11-18 Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 35–286（252 aa） Fragment：CCP DOMAINS 1-4, UNP RESIDUES 35-286
Not recorded EDO 1,2-ETHANEDIOL × 32 X-RAY DIFFRACTION
X-ray crystallization conditions 100MM AMMONIUM CITRATE 7% PEG 3350 5MM GLUTATHIONE 50MM BIS-TRIS PROPANE, PH 6.5
Resolution 2.40 Å R-free 0.219
8QK3 Human Adenovirus type 11 fiber knob in complex with its cell receptors, Desmoglein-2 and CD46 Deposited 2023-09-14 Assembly 1 Protein heterocomplex Heteromer；Protein × 5 PDB declaration: pentameric（5） Consistent with protein count
Chain E 1–392（392 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.20 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.