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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P15941 New Search
18PDB entries
27Biological assembly
30chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1SM3 CRYSTAL STRUCTURE OF THE TUMOR SPECIFIC ANTIBODY SM3 COMPLEX WITH ITS PEPTIDE EPITOPE Deposited 1997-12-23 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain P 139–151（13 aa）
Not recorded CD CADMIUM ION × 8 CL CHLORIDE ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 6；pH 6.0
Resolution 1.95 Å R-free 0.283
6BSB Crystal structure of the Mucin-1 SEA domain, L1105M mutant, Selenium-derivative Deposited 2017-12-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1041–1097（57 aa） Fragment：SEA domain, N-terminal
Chain B 1098–1152（55 aa） Fragment：SEA domain, C-terminal
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；Native crystals (see related entry) were used as seeds in a drop of 1:1 mix of the SeMet-derivative (9 mg/ml in 10 mM Tris-Cl, pH 7.4) and reservoir solution (0.1 M sodium acetate trihydrate pH 4.6, 1.75 M sodium chloride, 0.2 M ammonium sulfate).
Resolution 1.60 Å R-free 0.222
6BSC Crystal structure of the Mucin-1 SEA domain Deposited 2017-12-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1041–1097（57 aa） Fragment：SEA domain, N-terminal
Chain B 1098–1152（55 aa） Fragment：SEA domain, C-terminal
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 4.6；293 K；Drop was a 1:1 mix of protein (10 mg/ml in 10 mM Tris-Cl, pH 7.4) and reservoir solution (0.1 M sodium acetate trihydrate pH 4.6, 2.0 M sodium chloride)
Resolution 1.30 Å R-free 0.184
6FZQ Crystal structure of scFv-SM3 in complex with compound 3 Deposited 2018-03-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain P 141–146（6 aa）
Not recorded EDO 1,2-ETHANEDIOL × 10 EEN 2-deoxy-2-[(difluoroacetyl)amino]-alpha-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；PEG 3350 disodium hydrogen phosphate
Resolution 1.70 Å R-free 0.225
6FZR Crystal structure of scFv-SM3 in complex with compound 2 Deposited 2018-03-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain P 141–146（6 aa） Fragment：UNP residues 141-146
Not recorded EDO 1,2-ETHANEDIOL × 8 EEQ 2-deoxy-2-[(fluoroacetyl)amino]-alpha-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；PEG 3350 disodium hydrogen phosphate
Resolution 1.80 Å R-free 0.232
6TGG scFv-1SM3 in complex with glycopeptide containing an sp2-imino sugar Deposited 2019-11-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain P 141–146（6 aa）
Not recorded EDO 1,2-ETHANEDIOL × 4 N8W ~{N}-[(6~{S},7~{R},8~{S},8~{a}~{R})-7,8-bis(oxidanyl)-3-oxidanylidene-1,5,6,7,8,8~{a}-hexahydro-[1,3]oxazolo[3,4-a]pyridin-6-yl]ethanamide × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；PEG 3350 disodium hydrogen phosphate
Resolution 2.00 Å R-free 0.237
7Q4I Crystal structure of DmC1GalT1 in complex with UDP-Mn2+ and the APD-TGalNAc-RP Deposited 2021-10-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain F 141–146（6 aa）
Chain G 141–146（6 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) UDP URIDINE-5'-DIPHOSPHATE × 2 EDO 1,2-ETHANEDIOL × 3 MN MANGANESE (II) ION × 2 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；potassium thiocyanate, Polyethylene glycol monomethyl ether 2,000
Resolution 2.40 Å R-free 0.235
7V4W Crystal structure of Antibody 16A in complex with MUC1 peptide Deposited 2021-08-15 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 145–157（13 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；289 K；Di-sodium hydrogen phosphate 0.2M, PEG 3350 20%
Resolution 2.10 Å R-free 0.233
7V64 Crystal structure of Antibody 16A in complex with MUC1 Glycopeptide(GlycoT) Deposited 2021-08-19 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；289 K；1.0 M Lithium chloride, 0.1 M Tris pH 8.5, 20% PEG 6000
Resolution 1.56 Å R-free 0.203
7V7K Crystal structure of Antibody 16A in complex with MUC1 Glycopeptide(GlycoST) Deposited 2021-08-21 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8.5；289 K；1.0 M Lithium chloride, 0.1 M Tris pH 8.5, 20%(w/v) PEG 6000
Resolution 2.20 Å R-free 0.251
7V8Q Crystal structure of antibody 14A in complex with MUC1 Glycopeptide(GlycoT) Deposited 2021-08-23 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain G 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；Crystal screen D4=JCSG F7, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 20% v/v 2-Propanol, 20% w/v Polyethylene glycol 4000
Resolution 3.20 Å R-free 0.244
7V8Q Crystal structure of antibody 14A in complex with MUC1 Glycopeptide(GlycoT) Deposited 2021-08-23 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain H 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；Crystal screen D4=JCSG F7, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 20% v/v 2-Propanol, 20% w/v Polyethylene glycol 4000
Resolution 3.20 Å R-free 0.244
7V8Q Crystal structure of antibody 14A in complex with MUC1 Glycopeptide(GlycoT) Deposited 2021-08-23 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain I 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.6；289 K；Crystal screen D4=JCSG F7, 0.1 M Sodium citrate tribasic dihydrate pH 5.6, 20% v/v 2-Propanol, 20% w/v Polyethylene glycol 4000
Resolution 3.20 Å R-free 0.244
7VAC Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoST) Deposited 2021-08-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain G 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 3.50 Å R-free 0.219
7VAC Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoST) Deposited 2021-08-28 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain H 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 3.50 Å R-free 0.219
7VAC Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoST) Deposited 2021-08-28 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain I 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 3.50 Å R-free 0.219
7VAZ Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoS) Deposited 2021-08-30 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain G 145–157（13 aa）
Not recorded NGA 2-acetamido-2-deoxy-beta-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 2.73 Å R-free 0.264
7VAZ Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoS) Deposited 2021-08-30 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain E 145–157（13 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 2.73 Å R-free 0.264
7VAZ Crystal structure of antibody 14A in complex with MUC1 glycopeptide(GlycoS) Deposited 2021-08-30 Assembly 3 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain I 145–157（13 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 5.5；289 K；0.1 M Sodium citrate pH 5.5, Isopropanol 10%, PEG 4000 20%
Resolution 2.73 Å R-free 0.264
8AXH Crystal structure of a MUC1-like glycopeptide containing the unnatural L-4-hydroxynorvaline in complex with scFv-SM3 Deposited 2022-08-31 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 141–146（6 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 6 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；291 K；PEG 3350 disodium hydrogen phosphate
Resolution 1.85 Å R-free 0.206
8P6I Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope Deposited 2023-05-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 141–149（9 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.2；293 K；0.2M NaCl 20%w/v PEG 8K 0.1M Na Phos Cit pH 4.2
Resolution 2.50 Å R-free 0.254
8P6I Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope Deposited 2023-05-26 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain a 141–149（9 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 4.2；293 K；0.2M NaCl 20%w/v PEG 8K 0.1M Na Phos Cit pH 4.2
Resolution 2.50 Å R-free 0.254
8S6K Crystal structure of ScFv-G2D11 complexed to a bis-Tn glycopeptide Deposited 2024-02-27 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain M 127–133（7 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 7 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；291 K；lithium chloride Tris PEG 8000
Resolution 1.75 Å R-free 0.221
8S6K Crystal structure of ScFv-G2D11 complexed to a bis-Tn glycopeptide Deposited 2024-02-27 Assembly 2 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain N 127–133（7 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 5 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 8；291 K；lithium chloride Tris PEG 8000
Resolution 1.75 Å R-free 0.221
8S6T Crystal structure of Fab-3F1 complexed to a bis-STn glycopeptide Deposited 2024-02-28 Assembly 1 Other combination Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain C 126–138（13 aa）
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；291 K；Magnesium chloride hexahydrate calcium chloride dihydrate NDSB sodium HEPES MOPS ethylene glycol PEG 8000
Resolution 1.85 Å R-free 0.267
8S6V Crystal structure of Fab-2D9 chimera complexed to a bis-Tn glycopeptide Deposited 2024-02-28 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain M 127–135（9 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 4 SO4 SULFATE ION × 2 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；291 K；lithium sulfate Bis-Tris PEG 3350
Resolution 1.95 Å R-free 0.244
8S6V Crystal structure of Fab-2D9 chimera complexed to a bis-Tn glycopeptide Deposited 2024-02-28 Assembly 2 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain N 127–135（9 aa）
Non-standard monomer：Yes (specific site not provided by mmCIF) EDO 1,2-ETHANEDIOL × 7 SO4 SULFATE ION × 3 A2G 2-acetamido-2-deoxy-alpha-D-galactopyranose × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 5.5；291 K；lithium sulfate Bis-Tris PEG 3350
Resolution 1.95 Å R-free 0.244

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.