当前蛋白身份：P16452
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 7TVZ Cryo-EM structure of human band 3-protein 4.2 complex in diagonal conformation 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric（3） 与蛋白数一致 |
链 E
1–691（691 aa）
|
未记录 | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 LMT DODECYL-BETA-D-MALTOSIDE × 5 CLR CHOLESTEROL × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 3.60 Å |
| 7TW0 Cryo-EM structure of human band 3-protein 4.2 complex in vertical conformation 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 3 PDB 声明：trimeric（3） 与蛋白数一致 |
链 E
1–691（691 aa）
|
未记录 | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 4.60 Å |
| 7TW1 Cryo-EM structure of human band 3-protein 4.2 complex (B2P2vertical) 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 4 PDB 声明：tetrameric（4） 与蛋白数一致 |
链 E
1–691（691 aa）
链 F
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 4.60 Å |
| 7TW3 Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 4 PDB 声明：tetrameric（4） 与蛋白数一致 |
链 E
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 4.40 Å |
| 7TW5 Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 5 PDB 声明：pentameric（5） 与蛋白数一致 |
链 E
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 5.70 Å |
| 7TW6 Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell 提交 2022-02-06 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 6 PDB 声明：hexameric（6） 与蛋白数一致 |
链 E
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.5
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 5.60 Å |
| 7UZS Protein 4.2 (local refinement from consensus reconstruction of ankyrin complex classes) 提交 2022-05-09 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL and 0.01% ( w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds
|
分辨率 2.20 Å |
| 7V0K Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map) 提交 2022-05-10 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 10 PDB 声明：decameric（10） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | CLR CHOLESTEROL × 6 AJP Digitonin × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 PLC DIUNDECYL PHOSPHATIDYL CHOLINE × 2 PIO [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL, and 0.01% w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds
|
分辨率 2.40 Å |
| 7V0Q Local refinement of protein 4.2, class 1 of erythrocyte ankyrin-1 complex 提交 2022-05-10 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL, and 0.01% w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds.
|
分辨率 2.50 Å |
| 8CS9 Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex 提交 2022-05-12 | Assembly 1 其他组合 异源复合物；蛋白 × 18 PDB 声明：octadecameric（18） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | CLR CHOLESTEROL × 8 AJP Digitonin × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 PIO [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate × 6 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL, and 0.01% w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds
|
分辨率 2.74 Å |
| 8CSL Sub-tomogram averaging of erythrocyte ankyrin-1 complex 提交 2022-05-12 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 19 PDB 声明：nonadecameric（19） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；130 mM KCl, 10 mM HEPES, pH 7.4
cryo-EM玻璃化条件
冷冻剂 ETHANE
|
分辨率 25.00 Å |
| 8CSW Local refinement of protein 4.2 in Class 2 of erythrocyte ankyrin-1 complex 提交 2022-05-13 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | 未记录非水小分子 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL, and 0.01% w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds
|
分辨率 2.50 Å |
| 8CTE Class 2 of erythrocyte ankyrin-1 complex (Composite map) 提交 2022-05-14 | Assembly 1 蛋白异源复合物 异源复合物；蛋白 × 14 PDB 声明：tetradecameric（14） 与蛋白数一致 |
链 X
1–691（691 aa）
|
未记录 | CLR CHOLESTEROL × 10 AJP Digitonin × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 PIO [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate × 2 | ELECTRON MICROSCOPY |
cryo-EM缓冲液
pH 7.4；Final gel filtration buffer contained 0.05% w/v digitonin, 130 mM KCl, 20 mM HEPES, pH 7.4, 1 mM ATP, 1 mM MgCl2, 1 mM PMSF. Peak fractions were concentrated to 8 mg/mL, and 0.01% w/v glycyrrhizic acid was added immediately prior to vitrification.
cryo-EM玻璃化条件
冷冻剂 ETHANE；4-6 seconds, wait time 30 seconds
|
分辨率 2.90 Å |