Current Protein Identity:P17947 New Search
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
8E3K Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) Deposited 2022-08-17 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.28 Å R-free 0.151
8E3R Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) Deposited 2022-08-17 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.45 Å R-free 0.153
8E4H Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) Deposited 2022-08-18 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa)
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.39 Å R-free 0.153
8E5Y Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 Deposited 2022-08-22 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 5.4;293 K;100 mM Bis-Tris pH 5.4, 2% PEG 3350
Resolution 1.32 Å R-free 0.162
8EBH Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) Deposited 2022-08-31 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.33 Å R-free 0.174
8EE9 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) Deposited 2022-09-06 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.22 Å R-free 0.156
8EJ6 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAATGGGG) Deposited 2022-09-16 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.39 Å R-free 0.168
8EJ8 Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAAAGGAAGTGGG) Deposited 2022-09-16 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Mutation:Q226E GOL GLYCEROL × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.45 Å R-free 0.172
8EK3 Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG) Deposited 2022-09-19 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain (165-270)
Mutation:Q226E NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.38 Å R-free 0.167
8EK8 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAGAAGGG) Deposited 2022-09-20 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;293 K;200 mM Ammonium Acetate, 100 mM TRIS, pH=8.5, 25% PEG 3350
Resolution 2.63 Å R-free 0.280
8EK8 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAGAAGGG) Deposited 2022-09-20 Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain E 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;293 K;200 mM Ammonium Acetate, 100 mM TRIS, pH=8.5, 25% PEG 3350
Resolution 2.63 Å R-free 0.280
8EKJ Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAAGTGGG) Deposited 2022-09-21 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, 2% PEG 3350
Resolution 1.54 Å R-free 0.192
8EKU Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAATGGGG) Deposited 2022-09-22 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.52 Å R-free 0.188
8EKV Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) Deposited 2022-09-22 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.62 Å R-free 0.200
8EKZ Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGGAGAAGTAGG) Deposited 2022-09-22 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.42 Å R-free 0.166
8EM9 Human PU.1 ETS-Domain (165-270) Bound to d(AATAGGAGAAGTAGGG) Deposited 2022-09-27 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 2.34 Å R-free 0.270
8EMD Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAAGTGGG) Deposited 2022-09-27 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain (165-270)
Mutation:Q226E NA SODIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.55 Å R-free 0.202
8ENG Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (forward strand) Deposited 2022-09-29 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.25 Å R-free 0.158
8EO1 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (reverse strand) Deposited 2022-10-01 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.28 Å R-free 0.180
8EO4 Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Di-methylated CpG sites Deposited 2022-10-02 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG3350
Resolution 1.24 Å R-free 0.165
8EQG Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG) Deposited 2022-10-07 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.39 Å R-free 0.184
8EQK Human PU.1 ETS-Domain (165-270) Bound to d(AATAACCGGAAGTGGG) Deposited 2022-10-07 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 3 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.45 Å R-free 0.179
8EQL Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAACCGGAAGTGGG) Deposited 2022-10-07 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa)
Not recorded NA SODIUM ION × 2 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.52 Å R-free 0.195
8T9U Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG) Deposited 2023-06-26 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;100 mM Sodium Acetate, pH=4.6, 2% PEG 3350
Resolution 1.47 Å R-free 0.181
8UFF Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAAGTGGG) in Ternary Complex with DB1976 Deposited 2023-10-04 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded Y5U (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide) × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;295 K;100mM Sodium Acetate, pH=4.6, 2% PEG 3350 well solution mixed 1:1 with 250uM Protein/DNA Complex
Resolution 1.66 Å R-free 0.201
8UFK Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) Deposited 2023-10-04 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex
Resolution 2.41 Å R-free 0.266
8UFK Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) Deposited 2023-10-04 Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain E 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex
Resolution 2.41 Å R-free 0.266
8UFZ Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) in Ternary Complex with DB1976 Deposited 2023-10-05 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded Y5U (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide) × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex - Ligand incorporated via soaking at 500uM concentration 24h
Resolution 3.06 Å R-free 0.286
8UFZ Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGCGGAAGTG) in Ternary Complex with DB1976 Deposited 2023-10-05 Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain E 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded Y5U (2M,2'M)-2,2'-(selenophene-2,5-diyl)di(1H-benzimidazole-6-carboximidamide) × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex - Ligand incorporated via soaking at 500uM concentration 24h
Resolution 3.06 Å R-free 0.286
8UHK Human PU.1 ETS-Domain (165-270) Bound to d(AAAATAAAAGGAAGTG) Deposited 2023-10-09 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex
Resolution 3.08 Å R-free 0.304
8UHK Human PU.1 ETS-Domain (165-270) Bound to d(AAAATAAAAGGAAGTG) Deposited 2023-10-09 Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain E 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 8.5;295 K;100mM TRIS Base (HCl adjusted), pH=8.5, 200mM Ammonium Acetate, 24% PEG3350 1:1 hanging drop with 250uM protein/DNA complex
Resolution 3.08 Å R-free 0.304
8V9N Human PU.1 ETS-Domain (165-270) Bound to d(AATAGAAGGAAGTGGG) Deposited 2023-12-08 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;295 K;100mM Sodium Acetate, pH=4.6, 2% PEG3350
Resolution 1.78 Å R-free 0.208
8VDH Human PU.1 ETS-Domain (165-270) Bound to d(AATAGAAGGAAGTGGG) in Ternary Complex with DB2447 Deposited 2023-12-15 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded A1AAQ 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide) × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;295 K;100mM Sodium Acetate, pH=4.6, 2% PEG3350
Resolution 1.64 Å R-free 0.208
8VDI Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) in Ternary Complex with DB2447 Deposited 2023-12-15 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa)
Not recorded A1AAQ 4,4'-[pyridine-2,6-diylbis(methyleneoxy)]di(benzene-1-carboximidamide) × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;295 K;100mM Sodium Acetate, pH=4.6, 2% PEG3350
Resolution 1.93 Å R-free 0.202
9CK2 Human PU.1 minimal ETS Domain (165-258) bound to d(AATAAGCGGAAGTGGG) Deposited 2024-07-08 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–258(94 aa)
Not recorded NA SODIUM ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.71 Å R-free 0.184
9CMB Human PU.1 ETS Domain (165-270) bound to d(AATAAAAGGAAGTGGG) Deposited 2024-07-13 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain A 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;100 mM sodium cacodylate, pH 6.5, 200 mM zinc acetate and 2% PEG 600
Resolution 2.15 Å R-free 0.246
9CMB Human PU.1 ETS Domain (165-270) bound to d(AATAAAAGGAAGTGGG) Deposited 2024-07-13 Assembly 2 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain C 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded ZN ZINC ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 6.5;293 K;100 mM sodium cacodylate, pH 6.5, 200 mM zinc acetate and 2% PEG 600
Resolution 2.15 Å R-free 0.246
9OA4 Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGGAAGTGGG-3') d(5'-TCCCACTTTCGCTTAT-3') with a GT mismatch Deposited 2025-04-19 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.42 Å R-free 0.195
9OB0 Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGIAAGTGGG-3') d(5'-TCCCACTTTCGCTTAT-3') with an IT mismatch Deposited 2025-04-21 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 1.79 Å R-free 0.211
9YNZ Human PU.1 ETS-Domain (165-270) Bound to d(5'-AATAAGCGGAAGTGGG-3') d(5'-TCCCACT*CPD*CGCTTAT-3') Deposited 2025-10-13 Assembly 1 Protein–DNA Monomer;Protein × 1 PDB declaration: trimeric(3) Consistent with all polymers
Chain F 165–270(106 aa) Fragment:ETS-Domain UNP residues 165-270
Not recorded No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP;pH 4.6;293 K;2% PEG 3350, 100 mM Sodium Acetate, pH 4.6
Resolution 2.05 Å R-free 0.244