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Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P21404 New Search
13PDB entries
22Biological assembly
81chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-MERIC（240） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 120 MYR MYRISTIC ACID × 60 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 2 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 2 MYR MYRISTIC ACID × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 3 Protein homooligomer Homooligomer；Protein × 20 PDB declaration: eicosameric（20） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 10 MYR MYRISTIC ACID × 5 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 4 Protein homooligomer Homooligomer；Protein × 24 PDB declaration: 24-meric（24） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 12 MYR MYRISTIC ACID × 6 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 5 Protein homooligomer Homooligomer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 2 MYR MYRISTIC ACID × 1 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
1D4M THE CRYSTAL STRUCTURE OF COXSACKIEVIRUS A9 TO 2.9 A RESOLUTION Deposited 1999-10-04 Assembly 6 Protein homooligomer Homooligomer；Protein × 120 PDB declaration: 120-meric（120） Consistent with protein count
Chain 1 568–866（299 aa） Fragment：VP1
Chain 2 69–329（261 aa） Fragment：VP2
Chain 3 330–567（238 aa） Fragment：VP3
Chain 4 1–68（68 aa） Fragment：VP4
Not recorded W71 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE × 60 MYR MYRISTIC ACID × 30 X-RAY DIFFRACTION mmCIF provides none of the parsed conditions Resolution 2.90 Å
3J2J Empty coxsackievirus A9 capsid Deposited 2012-10-04 Assembly 1 Protein homooligomer Homooligomer；Protein × 180 PDB declaration: 180-meric（180） Consistent with protein count
Chain A 631–852（222 aa） Fragment：UNP residues 631-852
Chain B 331–568（238 aa） Fragment：UNP residues 331-568
Chain C 79–330（252 aa） Fragment：UNP residues 79-330
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM vitrification conditions manual plunging；Cryogen ETHANE；manual plunging into liquid ethane (GATAN CRYOPLUNGE 3)
Resolution 9.54 Å
3J2J Empty coxsackievirus A9 capsid Deposited 2012-10-04 Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 631–852（222 aa） Fragment：UNP residues 631-852
Chain B 331–568（238 aa） Fragment：UNP residues 331-568
Chain C 79–330（252 aa） Fragment：UNP residues 79-330
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM vitrification conditions manual plunging；Cryogen ETHANE；manual plunging into liquid ethane (GATAN CRYOPLUNGE 3)
Resolution 9.54 Å
3J2J Empty coxsackievirus A9 capsid Deposited 2012-10-04 Assembly 3 Protein homooligomer Homooligomer；Protein × 15 PDB declaration: pentadecameric（15） Consistent with protein count
Chain A 631–852（222 aa） Fragment：UNP residues 631-852
Chain B 331–568（238 aa） Fragment：UNP residues 331-568
Chain C 79–330（252 aa） Fragment：UNP residues 79-330
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM vitrification conditions manual plunging；Cryogen ETHANE；manual plunging into liquid ethane (GATAN CRYOPLUNGE 3)
Resolution 9.54 Å
3J2J Empty coxsackievirus A9 capsid Deposited 2012-10-04 Assembly 4 Protein homooligomer Homooligomer；Protein × 18 PDB declaration: octadecameric（18） Consistent with protein count
Chain A 631–852（222 aa） Fragment：UNP residues 631-852
Chain B 331–568（238 aa） Fragment：UNP residues 331-568
Chain C 79–330（252 aa） Fragment：UNP residues 79-330
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM vitrification conditions manual plunging；Cryogen ETHANE；manual plunging into liquid ethane (GATAN CRYOPLUNGE 3)
Resolution 9.54 Å
3J2J Empty coxsackievirus A9 capsid Deposited 2012-10-04 Assembly 5 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain A 631–852（222 aa） Fragment：UNP residues 631-852
Chain B 331–568（238 aa） Fragment：UNP residues 331-568
Chain C 79–330（252 aa） Fragment：UNP residues 79-330
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM vitrification conditions manual plunging；Cryogen ETHANE；manual plunging into liquid ethane (GATAN CRYOPLUNGE 3)
Resolution 9.54 Å
8AT5 native Coxsackievirus A9 Deposited 2022-08-22 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded MYR MYRISTIC ACID × 60 PLM PALMITIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.25；PBS containing 2mM MgCl2, pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 2.90 Å
8AW6 Expanded Coxsackievirus A9 after 0.01% faf-BSA treatment Deposited 2022-08-29 Assembly 1 Protein homooligomer Homooligomer；Protein × 180 PDB declaration: 180-meric（180） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.25；DPBS containing 0.01% faf-BSA, pH 7.25, incubated at 37 C for 1 h
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.50 Å
8AXX Expanded Coxsackievirus A9 after treatment with endosomal ionic buffer Deposited 2022-09-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 180 PDB declaration: 180-meric（180） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Not recorded No recorded non-water small molecule ELECTRON MICROSCOPY
cryo-EM buffer pH 7.25；endosomal ionic composition buffer, pH 7.25, incubated at 37 C for 3 h 20 mM NaCl, 6 mM KH2PO4, 12 mM K2HPO4, 0.5 mM MgCl2, 0.45 mM CaCl2
cryo-EM vitrification conditions Cryogen ETHANE
Resolution 3.30 Å
8S7J Coxsackievirus A9 bound with compound 20 (CL300) Deposited 2024-03-01 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1H9Q ~{N}-[(4-methoxyphenyl)methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 MYR MYRISTIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2；PBS containing 2 mM MgCl2 and 5% DMSO.
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.26 Å
9EXI Coxsackievirus A9 bound with compound 14 (CL275) Deposited 2024-04-08 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–851（283 aa）
Chain B 79–329（251 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1H8J 4-[(4-methylpiperazin-1-yl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]aniline × 60 MYR MYRISTIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2；PBS containing 2 mM MgCl2 and 5% DMSO.
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.31 Å
9FA9 Coxsackievirus A9 bound with compound 16 (CL298) Deposited 2024-05-10 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–851（283 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1IBS ~{N}-[(2-fluorophenyl)methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.75 Å
9FCZ Coxsackievirus A9 bound with compound 17 (CL301) Deposited 2024-05-16 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–851（283 aa）
Chain B 79–329（251 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1IB2 ~{N}-[(3-fluorophenyl)methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 MYR MYRISTIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2；PBS containing 2 mM MgCl2 and 5% DMSO.
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.53 Å
9FGN Coxsackievirus A9 bound with compound 18 (CL304) Deposited 2024-05-24 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–850（282 aa）
Chain B 79–328（250 aa）
Chain C 332–567（236 aa）
Chain D 2–68（67 aa）
Not recorded A1ICH ~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2；PBS containing 2 mM MgCl2 and 5% DMSO.
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.64 Å
9FO2 Coxsackievirus A9 bound with compound 15 (CL278) Deposited 2024-06-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 79–329（251 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1IEI ~{N}-[(4-fluorophenyl)methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 MYR MYRISTIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE；Sample was blotted from the front for 1.5 s.
Resolution 2.58 Å
9FO5 Coxsackievirus A9 bound with compound 19 (CL313) Deposited 2024-06-11 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded A1IEH ~{N}-[[3,4-bis(fluoranyl)phenyl]methyl]-4-[(4-methylpiperazin-1-yl)methyl]aniline × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.69 Å
9FP5 Coxsackievirus A9 bound with CL213. Deposited 2024-06-13 Assembly 1 Protein homooligomer Homooligomer；Protein × 240 PDB declaration: 240-meric（240） Consistent with protein count
Chain A 569–867（299 aa）
Chain B 70–330（261 aa）
Chain C 331–568（238 aa）
Chain D 2–69（68 aa）
Not recorded PLM PALMITIC ACID × 60 MYR MYRISTIC ACID × 60 ELECTRON MICROSCOPY
cryo-EM buffer pH 7.2
cryo-EM vitrification conditions Cryogen ETHANE；Sample was incubated for 15 s on the grid before blotted from the front for 1.5 s.
Resolution 2.50 Å

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.