当前蛋白身份：P35747
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差异标签只比较当前检索结果；所有PDB和assembly原始记录仍分别保留。
相关结构差异明细
一行代表一个 PDB 条目中的一个 biological assembly；同一蛋白的多个单体会分别列出。
| PDB 条目 | Assembly / 聚集状态 | 构建体 | 突变与修饰 | 配体、离子与非聚合物 | 实验方法 | 实验环境 | 结构质量 |
|---|---|---|---|---|---|---|---|
| 3V08 Crystal structure of Equine Serum Albumin 提交 2011-12-07 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | BR BROMIDE ION × 11 SO4 SULFATE ION × 6 EDO 1,2-ETHANEDIOL × 1 UNX UNKNOWN LIGAND × 12 PG4 TETRAETHYLENE GLYCOL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；289 K；1.9 M NH4 sulfate, 2.5% PEG8000, 0.1 M NaBr, 0.1 M Tris HCl, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 289K
|
分辨率 2.45 Å R-free 0.245 |
| 4F5T Crystal Structure of Equine Serum Albumin 提交 2012-05-13 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：UNP residues 25-607
|
未记录 | ACT ACETATE ION × 6 SO4 SULFATE ION × 4 GOL GLYCEROL × 8 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；1.7 M ammonium sulfate, 0.1M acetate buffer pH 4.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.32 Å R-free 0.259 |
| 4F5U Crystal structure of Equine Serum Albumin at 2.04 resolution 提交 2012-05-13 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：UNP residues 25-607
|
未记录 | MLI MALONATE ION × 6 SIN SUCCINIC ACID × 1 LMR (2S)-2-hydroxybutanedioic acid × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；80% Tacsimate, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.04 Å R-free 0.243 |
| 4J2V Crystal Structure of Equine Serum Albumin in complex with 3,5-diiodosalicylic acid 提交 2013-02-05 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：UNP residues 25-607
|
未记录 | DIU 2-HYDROXY-3,5-DIIODO-BENZOIC ACID × 4 MLI MALONATE ION × 7 FMT FORMIC ACID × 8 ACT ACETATE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6；293 K；85% Tacsimate, cocrystallization with 3,5-diiodosalicylic acid, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.12 Å R-free 0.238 |
| 4OT2 Crystal Structure of Equine Serum Albumin in complex with Naproxen 提交 2014-02-13 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：UNP residues 25-607
|
未记录 | NPS (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid × 2 SIN SUCCINIC ACID × 1 ACT ACETATE ION × 2 MLI MALONATE ION × 4 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 4.5；293 K；1.6 M Ammonium sulfate, 0.1 M acetate buffer pH 4.5, cocrystallization with Naproxen, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
分辨率 2.42 Å R-free 0.247 |
| 5DQF Horse Serum Albumin (ESA) in complex with Cetirizine 提交 2015-09-14 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
28–607（580 aa）
|
突变：R561A | PG4 TETRAETHYLENE GLYCOL × 7 SO4 SULFATE ION × 4 LCR (2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid × 1 CZE (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid × 1 CL CHLORIDE ION × 4 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.5；289 K；1 ul of 30 mg/mL protein in 10 mM Tris pH 7.5, 150 mM NaCl was mixed with 1ul of the well condition: 100 mM Tris pH 7.5, 1800 mM (NH4)2SO4, 87.5 mM NaBr, 2.5% w/v PEG 8K
|
分辨率 2.15 Å R-free 0.241 |
| 5HOZ Crystal structure of Equine Serum Albumin (ESA) at pH 9.0 提交 2016-01-19 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
突变：R561A | 未记录非水小分子 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 9；289 K；1 ul of 32 mg/ml protein in 10 mM Tris pH 7.5, 150 mM NaCl was mixed with 1 ul of the well condition (100 mM Tris, 2.4 M Ammonium phosphate, final pH 9.0) and equilibrated against well solution on 15-well Crystallization Plate (Qiagen)
|
分辨率 2.15 Å R-free 0.239 |
| 5IIH Crystal structure of Equine Serum Albumin in the presence of 2.5 mM zinc at pH 7.4 提交 2016-03-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：residues 25-607
|
未记录 | ZN ZINC ION × 1 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.4；289 K；1 ul of 30 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl pH 7.4, 2.0 M (NH4)2SO4, 5 mM ZnCl2) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen)
|
分辨率 2.40 Å R-free 0.235 |
| 5IIU Crystal structure of Equine Serum Albumin in the presence of 10 mM zinc at pH 6.9 提交 2016-03-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：residues 25-607
|
未记录 | ZN ZINC ION × 10 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.9；289 K；1 ul of 30 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4, 5 mM ZnCl2, final pH 6.9) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 50 mM ZnCl2 in 100 mM Tris, final pH 6.9, to final concentration of 10 mM
|
分辨率 2.30 Å R-free 0.239 |
| 5IIX Crystal structure of Equine Serum Albumin in the presence of 15 mM zinc at pH 6.5 提交 2016-03-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：residues 25-607
|
未记录 | ZN ZINC ION × 11 UNL UNKNOWN LIGAND × 2 SO4 SULFATE ION × 6 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6.5；289 K；1 ul of 30 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4, 5 mM ZnCl2, final pH 6.5) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 50 mM ZnCl2 in 100 mM Tris, final pH 6.5, to final concentration of 15 mM
|
分辨率 2.20 Å R-free 0.228 |
| 5IJ5 Crystal structure of Equine Serum Albumin in the presence of 50 mM zinc at pH 4.5 提交 2016-03-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：residues 25-607
|
未记录 | ZN ZINC ION × 15 GOL GLYCEROL × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 4.5；289 K；1 ul of 30 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (2.0 M (NH4)2SO4, 0.1 M Na acetate, 0.1 M ZnCl2, final pH 4.5) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen)
|
分辨率 2.55 Å R-free 0.253 |
| 5IJE Crystal structure of Equine Serum Albumin in the presence of 30 mM zinc at pH 7.4 提交 2016-03-01 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：residues 25-607
|
未记录 | ZN ZINC ION × 13 SO4 SULFATE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.4；289 K；1 ul of 30 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4, 5 mM ZnCl2, final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 100 mM ZnCl2 in 100 mM Tris, final pH 7.4, to final concentration of 100 mM
|
分辨率 2.40 Å R-free 0.255 |
| 5V0V Crystal structure of Equine Serum Albumin complex with etodolac 提交 2017-02-28 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
片段：UNP residues 25-607
|
未记录 | TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 4 SO4 SULFATE ION × 7 8QP [(1S)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid × 2 8QS [(1R)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetic acid × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.4；289 K；1 ul of 34 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4 final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 10 mM Etodolac.
|
分辨率 2.45 Å R-free 0.238 |
| 6CI6 Crystal structure of equine serum albumin in complex with nabumetone 提交 2018-02-23 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | SO4 SULFATE ION × 5 NBO nabumetone × 2 TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 KNA nonanoic acid × 1 UNX UNKNOWN LIGAND × 8 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.4；289 K；1 ul of 34 mg/ml protein in 10 mM Tris pH 7.4 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.2 M (NH4)2SO4 final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 10 mM nabumetone
|
分辨率 2.80 Å R-free 0.256 |
| 6MDQ Crystal structure of equine serum albumin in complex with testosterone 提交 2018-09-05 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | FLC CITRATE ANION × 3 TES TESTOSTERONE × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7；289 K；0.2 ul of 15 mg/ml protein was mixed with 0.2 ul of the well condition (1.8 M ammonium dihydrogen citrate, pH 7.0) and equilibrated against well solution in 96-Well sitting drop crystallization plate (Swissci). Testosterone powder was added to the crystallization drop
|
分辨率 2.15 Å R-free 0.226 |
| 6U4R Crystal structure of Equine Serum Albumin complex with ketoprofen 提交 2019-08-26 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | 9KL (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid × 3 KNA nonanoic acid × 1 UNX UNKNOWN LIGAND × 3 UNL UNKNOWN LIGAND × 1 SO4 SULFATE ION × 3 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7.4；298 K；1 ul of 35 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4 final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 3mM ketoprofen.
|
分辨率 2.45 Å R-free 0.233 |
| 6U4X Crystal structure of Equine Serum Albumin complex with ibuprofen 提交 2019-08-26 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | UNL UNKNOWN LIGAND × 1 UNX UNKNOWN LIGAND × 9 IBP IBUPROFEN × 2 SO4 SULFATE ION × 10 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；289 K；1 ul of 36 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.4 M (NH4)2SO4 final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Ibuprofen powder was added to the crystallization drop.
|
分辨率 2.25 Å R-free 0.238 |
| 6U5A Crystal structure of Equine Serum Albumin complex with 6-MNA 提交 2019-08-27 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | UNX UNKNOWN LIGAND × 7 PWY (6-methoxynaphthalen-2-yl)acetic acid × 3 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；289 K；1 ul of 35 mg/ml protein in 10 mM Tris pH 7.5 and 150 mM NaCl buffer was mixed with 1 ul of the well condition (0.2 M Li2SO4, 0.1 M Tris:HCl, 2.0 M (NH4)2SO4 final pH 7.4) and equilibrated against well solution in 15 Well Crystallization Plate (Qiagen). Crystals were soaked with 3 mM 6-MNA.
|
分辨率 2.65 Å R-free 0.256 |
| 6XK0 Albumin-dexamethasone complex 提交 2020-06-24 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
非标准单体：是（mmCIF未提供具体位点） | DEX DEXAMETHASONE × 1 FLC CITRATE ANION × 1 MYR MYRISTIC ACID × 1 UNX UNKNOWN LIGAND × 4 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 7；289 K；Prior to crystallization, 15 mg/ml protein was incubated with dexamethasone powder (10-fold molar excess) for 60 min at room temperature, and the mixture with the powder in suspension was used for crystallization. 1 ul of this mixture was mixed with 1 ul of the well condition (1.8 M ammonium dihydrogen citrate, pH 7.0) and equilibrated against the well solution in 15-Well hanging drop crystallization plate (Qiagen, EasyXtal). 1:1 mixture of Paratone N and mineral oil was used as a cryoprotectant
|
分辨率 2.40 Å R-free 0.249 |
| 7MBL Crystal structure of Equine Serum Albumin in complex with Cobalt (II) 提交 2021-03-31 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | CO COBALT (II) ION × 5 SO4 SULFATE ION × 4 | X-RAY DIFFRACTION |
X-ray结晶条件
COUNTER-DIFFUSION；pH 7.4；291 K；Protein: 1 uL of 34 mg/mL ESA dissolved in 10 mM Tris (pH 7.4) and 150 mM NaCl.
Precipitant: 1 uL of 0.2 M lithium sulfate, 2.0 M ammonium sulfate, 0.1 M Tris pH 7.4.
15-Well hanging drop crystallization plate (Qiagen, EasyXtal).
3.3 uL of 50 mM cobalt (II) chloride dissolved in the reservoir solution were added directly to the 2 uL crystallization drop containing crystals to reach a final cobalt concentration of 31 mM and then incubated for a few hours before harvesting.
Paratone was used as a cryoprotectant
|
分辨率 2.70 Å R-free 0.289 |
| 9S42 Complex of Equine Serum Albumin with Hydrolyzed Ampicillin 提交 2025-07-25 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | ZZ7 (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid × 1 FMT FORMIC ACID × 3 LMR (2S)-2-hydroxybutanedioic acid × 1 SIN SUCCINIC ACID × 1 ACT ACETATE ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；80% v/v Tacsimate, pH 6.0
|
分辨率 2.32 Å R-free 0.246 |
| 9S43 Complex of Equine Serum Albumin with Oxacillin 提交 2025-07-25 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | A1JLX (2~{R},5~{R},6~{S})-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonylamino]-7-oxidanylidene-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid × 1 LMR (2S)-2-hydroxybutanedioic acid × 2 ACT ACETATE ION × 3 MLI MALONATE ION × 9 FMT FORMIC ACID × 4 SIN SUCCINIC ACID × 3 CA CALCIUM ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5；291 K；2.0 M ammonium sulfate, 0.1 M acetate buffer at pH 5.0 and then crystal was cryoprotected by 85% Tacsimate at pH 6.0
|
分辨率 2.03 Å R-free 0.206 |
| 9S73 Complex of Equine Serum Albumin with Ampicillin 提交 2025-08-02 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | ACT ACETATE ION × 1 FMT FORMIC ACID × 9 AIC (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID × 1 MLI MALONATE ION × 1 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, HANGING DROP；pH 5；291 K；2.0 M ammonium sulfate, 0.1 M acetate buffer pH 5.0
|
分辨率 2.50 Å R-free 0.263 |
| 9ZMD Equine Serum Albumin with Copper(II) 提交 2025-12-10 | Assembly 1 蛋白单体 单体；蛋白 × 1 PDB 声明：monomeric（1） 与蛋白数一致 |
链 A
25–607（583 aa）
|
未记录 | CU COPPER (II) ION × 6 SO4 SULFATE ION × 7 NA SODIUM ION × 2 | X-RAY DIFFRACTION |
X-ray结晶条件
VAPOR DIFFUSION, SITTING DROP；pH 7.4；291.15 K；0.2 M lithium sulfate, 0.1 M Tris-HCl, pH 7.4, 2.2 M ammonium sulfate, 5 mM copper(II) chloride mixed 1:1 with 36 mg/mL protein, 10 mM Tris-HCl, 150 mM sodium chloride
|
分辨率 2.65 Å R-free 0.251 |