Current Protein Identity：P35956
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 3HPG Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces Deposited 2009-06-04 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain A
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain B
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain E
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain F
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.6；291 K；25-30% Jeffamine M600, 100mM Bis-Tris propane-HCl, pH6.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.28 Å R-free 0.253 |
| 3HPG Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces Deposited 2009-06-04 | Assembly 2 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain C
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain D
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain E
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain F
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.6；291 K；25-30% Jeffamine M600, 100mM Bis-Tris propane-HCl, pH6.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.28 Å R-free 0.253 |
| 3HPG Visna virus integrase (residues 1-219) in complex with LEDGF IBD: examples of open integrase dimer-dimer interfaces Deposited 2009-06-04 | Assembly 3 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain A
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain B
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain C
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
Chain D
823–1039（217 aa）
Fragment：N-terminal and catalytic core domains, UNP residues 823-1039
|
Not recorded | ZN ZINC ION × 4 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.6；291 K；25-30% Jeffamine M600, 100mM Bis-Tris propane-HCl, pH6.6, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 3.28 Å R-free 0.253 |
| 3HPH Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD Deposited 2009-06-04 | Assembly 1 Protein heterocomplex Heteromer；Protein × 8 PDB declaration: octameric（8） Consistent with protein count |
Chain A
823–1039（217 aa）
Fragment：N-terminal and catalytic domains, UNP residues 923-1039
Chain B
823–1039（217 aa）
Fragment：N-terminal and catalytic domains, UNP residues 923-1039
Chain C
823–1039（217 aa）
Fragment：N-terminal and catalytic domains, UNP residues 923-1039
Chain D
823–1039（217 aa）
Fragment：N-terminal and catalytic domains, UNP residues 923-1039
|
Not recorded | ZN ZINC ION × 4 GOL GLYCEROL × 4 PO4 PHOSPHATE ION × 3 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；291 K；0.7-0.9M (NH4)2HPO4, 2.5% Jeffamine M600,100mM Bis-Tris propane-HCl, pH7.0, VAPOR DIFFUSION, HANGING DROP, temperature 291K
|
Resolution 2.64 Å R-free 0.253 |
| 5LLJ Maedi-Visna virus (MVV) integrase C-terminal domain (residues 220-276) Deposited 2016-07-27 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
1039–1096（58 aa）
Chain B
1039–1096（58 aa）
|
Not recorded | CL CHLORIDE ION × 1 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7.5；291 K；0.2M potassium sodium tartrate 0.1M BTP pH 7.5 20% PEG-3350
|
Resolution 1.78 Å R-free 0.234 |
| 5M0R Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex Deposited 2016-10-05 | Assembly 1 Protein–DNA Homooligomer；Protein × 16 PDB declaration: 22-meric（22） Consistent with all polymers |
Chain A
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain B
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain C
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain D
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain E
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain F
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain G
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain H
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain I
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain J
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain K
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain L
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain M
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain N
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain O
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain P
821–1101（281 aa）
Fragment：UNP residues 821-1101
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 6.5
cryo-EM vitrification conditions
Cryogen ETHANE；To lower salt concentration before plunge-freezing, the grids were blotted for 0.5 s, immediately hydrated with a 4-ul drop of 200 mM NaCl, 3 mM CaCl2 and 25 mM BisTris-HCl pH 6.5 and blotted again for 2.5 s followed by plunging into liquid ethane.
|
Resolution 8.20 Å |
| 5T3A Maedi-Visna virus (MVV) integrase CCD-CTD (residues 60-275) Deposited 2016-08-25 | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count |
Chain A
880–1101（222 aa）
|
Not recorded | ACT ACETATE ION × 6 MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；0.1M Mes pH6.0, 15-100mM calcium acetate and 15-21% PEG 400
|
Resolution 2.50 Å R-free 0.240 |
| 7U32 MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution Deposited 2022-02-25 | Assembly 1 Protein–DNA Homooligomer；Protein × 16 PDB declaration: eicosameric（20） Consistent with all polymers |
Chain A
1226–1506（281 aa）
Chain B
1226–1506（281 aa）
Chain C
1226–1506（281 aa）
Chain D
1226–1506（281 aa）
Chain E
1226–1506（281 aa）
Chain F
1226–1506（281 aa）
Chain G
1226–1506（281 aa）
Chain H
1226–1506（281 aa）
Chain I
1226–1506（281 aa）
Chain J
1226–1506（281 aa）
Chain K
1226–1506（281 aa）
Chain L
1226–1506（281 aa）
Chain M
1226–1506（281 aa）
Chain N
1226–1506（281 aa）
Chain O
1226–1506（281 aa）
Chain P
1226–1506（281 aa）
|
Not recorded | ZN ZINC ION × 12 CA CALCIUM ION × 2 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 6.5
cryo-EM vitrification conditions
Cryogen ETHANE；Cryo-EM grids were prepared by freezing using a manual plunger in cold room at 4C
|
Resolution 3.46 Å |
| 7Z1Z MVV strand transfer complex (STC) intasome in complex with LEDGF/p75 at 3.5 A resolution Deposited 2022-02-25 | Assembly 1 Protein–DNA Heteromer；Protein × 18 PDB declaration: 24-meric（24） Consistent with all polymers |
Chain A
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain B
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain C
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain D
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain E
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain F
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain G
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain H
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain I
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain J
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain K
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain L
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain M
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain N
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain O
821–1101（281 aa）
Fragment：UNP residues 821-1101
Chain P
821–1101（281 aa）
Fragment：UNP residues 821-1101
|
Not recorded | ZN ZINC ION × 12 | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 6.5；310 mM NaCl, 3 mM CaCl2, 25 mM BisTris-HCl, pH 6.5.
cryo-EM vitrification conditions
Cryogen ETHANE
|
Resolution 3.50 Å |
| 7ZPP Cryo-EM structure of the MVV CSC intasome at 4.5A resolution Deposited 2022-04-28 | Assembly 1 Protein–DNA Homooligomer；Protein × 16 PDB declaration: eicosameric（20） Consistent with all polymers |
Chain A
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain B
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain C
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain D
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain E
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain F
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain G
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain H
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain I
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain J
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain K
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain L
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain M
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain N
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain O
1226–1506（281 aa）
Fragment：UNP residues 821-1101
Chain P
1226–1506（281 aa）
Fragment：UNP residues 821-1101
|
Not recorded | No recorded non-water small molecule | ELECTRON MICROSCOPY |
cryo-EM buffer
pH 6.5；1 M NaCl, 3 mM CaCl2 and 25 mM BisTris-HCl, pH 6.5
cryo-EM vitrification conditions
Cryogen ETHANE；To lower salt concentration before plunge-freezing, the grids were blotted for 0.5 s, immediately hydrated with a 4-ul drop of 200 mM NaCl, 3 mM CaCl2 and 25 mM BisTris-HCl pH 6.5 and blotted again for 2.5 s followed by plunging into liquid ethane.
|
Resolution 4.50 Å |