← Back to search

Protein Structures and Oligomeric States

Enter a protein name, UniProt accession or PDB ID. Name searches ask you to confirm the protein identity before related structures are queried.

Current Protein Identity：P40692 New Search
7PDB entries
7Biological assembly
12chain/assembly records
Main Difference Dimensions in This Set
Different construct Different mutation/modification Different assembly state Different ligand/ion Different experimental conditions Different structure-quality metrics

Difference tags compare only the current result set; every original PDB and assembly record remains separate.

Related-Structure Differences

Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.

PDB Entry Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Experimental Method Experimental Conditions Structure Quality
3RBN Crystal structure of MutL protein homolog 1 isoform 1 [Homo sapiens] Deposited 2011-03-29 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 486–751（266 aa） Fragment：UNP residues 486-751
Chain B 486–751（266 aa） Fragment：UNP residues 486-751
Non-standard monomer：Yes (specific site not provided by mmCIF) Non-standard monomer：Yes (specific site not provided by mmCIF) No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 8；293 K；22% PEG4000, 0.2 M sodium acetate, 0.1 M Tris-HCl, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K
Resolution 2.16 Å R-free 0.251
4P7A Crystal Structure of human MLH1 Deposited 2014-03-26 Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain A 1–347（347 aa）
Not recorded MG MAGNESIUM ION × 2 ADP ADENOSINE-5'-DIPHOSPHATE × 2 UNX UNKNOWN LIGAND × 18 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, SITTING DROP；pH 7.5；293 K；20% PEG4000, 10% ISOPROPANOL, 0.1 M HEPES
Resolution 2.30 Å R-free 0.254
5U5P Crystal Structure and X-ray Diffraction Data Collection of Importin-alpha from Mus Musculus Complexed with a MLH1 NLS Peptide Deposited 2016-12-07 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 467–476（10 aa）
Chain C 467–476（10 aa）
Not recorded DTT 2,3-DIHYDROXY-1,4-DITHIOBUTANE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；291 K；0.600-0.625 M sodium citrate (pH 6) 10 mM DTT
Resolution 2.17 Å R-free 0.211
6WBA Structure of Mouse Importin alpha MLH1- R470A NLS Peptide Complex Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 466–476（11 aa） Fragment：NLS peptide
Chain C 466–476（11 aa） Fragment：NLS peptide
Mutation：R470A Mutation：R470A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；0.1 M sodium citrate (pH 6), 0.6 M sodium citrate and 10 mM DTT
Resolution 2.15 Å R-free 0.197
6WBB Structure of Mouse Importin alpha - MLH1-E475A NLS peptide complex Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 466–476（11 aa） Fragment：NLS peptide
Chain C 466–476（11 aa） Fragment：NLS peptide
Mutation：E475A Mutation：E475A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；0.1 M sodium citrate (pH 6), 10 mM DTT, 0.55 M sodium citrate
Resolution 2.66 Å R-free 0.227
6WBC Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex Deposited 2020-03-26 Assembly 1 Protein heterocomplex Heteromer；Protein × 2 PDB declaration: dimeric（2） Consistent with protein count
Chain B 466–476（11 aa） Fragment：NLS peptide
Mutation：R472K No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；0.1 M sodium citrate (pH 6), 0.575 M sodium citrate , 10 mM DTT
Resolution 2.15 Å R-free 0.213
7M60 Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex Deposited 2021-03-25 Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric（3） Consistent with protein count
Chain B 466–476（11 aa） Fragment：residues 466-476
Chain C 466–476（11 aa） Fragment：residues 466-476
Mutation：S467A Mutation：S467A No recorded non-water small molecule X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 6；291 K；0.1M sodium citrate pH6, 0.65 M sodium citrate, 10 mM DTT
Resolution 2.30 Å R-free 0.207

This page presents structural evidence recorded in PDB/mmCIF.“No recorded non-water small molecule” does not prove that the experimental sample was ligand-free; experimental conditions belong to the PDB experiment, while ligands and copy counts are shown for each biological assembly.