Current Protein Identity：P49767
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Difference tags compare only the current result set; every original PDB and assembly record remains separate.
Related-Structure Differences
Each row represents one biological assembly in one PDB entry; multiple monomers of the same protein are listed separately.
| PDB Entry | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Experimental Method | Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 2X1W Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2 Deposited 2010-01-08 | Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain A
112–215（104 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 112-215
Chain B
112–215（104 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 112-215
|
Mutation：YES Mutation：YES | CS CESIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.2；100 MM MES BUFFER, PH 5.0-5.6, 50 MM CSCL AND 28-32 % (W/V) JEFFAMINE 600.
|
Resolution 2.70 Å R-free 0.280 |
| 2X1W Crystal Structure of VEGF-C in Complex with Domains 2 and 3 of VEGFR2 Deposited 2010-01-08 | Assembly 2 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
112–215（104 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 112-215
Chain D
112–215（104 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 112-215
|
Mutation：YES Mutation：YES | CS CESIUM ION × 1 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 5.2；100 MM MES BUFFER, PH 5.0-5.6, 50 MM CSCL AND 28-32 % (W/V) JEFFAMINE 600.
|
Resolution 2.70 Å R-free 0.280 |
| 2X1X CRYSTAL STRUCTURE OF VEGF-C IN COMPLEX WITH DOMAINS 2 AND 3 OF VEGFR2 IN A TETRAGONAL CRYSTAL FORM Deposited 2010-01-08 | Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain E
112–215（104 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 112-215
|
Mutation：YES | HG MERCURY (II) ION × 2 NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 | X-RAY DIFFRACTION |
X-ray crystallization conditions
pH 4.6；100 MM NA-ACETATE BUFFER, PH 4.4-4.8, 50 MM CSCL, 28-32 % (W/V) JEFFAMINE 600
|
Resolution 3.10 Å R-free 0.334 |
| 4BSK Crystal structure of VEGF-C in complex with VEGFR-3 domains D1-2 Deposited 2013-06-10 | Assembly 1 Other combination Heteromer；Protein × 4 PDB declaration: tetrameric（4） Consistent with protein count |
Chain C
103–215（113 aa）
Fragment：VEGF HOMOLOGY DOMAIN, RESIDUES 103-215
|
Mutation：YES | NAG 2-acetamido-2-deoxy-beta-D-glucopyranose × 8 | X-RAY DIFFRACTION |
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 9；SITTING DROPS AT ROOM TEMPERATURE OVER A RESERVOIR SOLUTION OF 0.1 M BIS-TRIS BUFFER AT PH 8.5-9.5 AND 1.0-1.5 M AMMONIUM SULPHATE.
|
Resolution 4.20 Å R-free 0.372 |